STRINGSTRING
AFUA_5G07180 AFUA_5G07180 AFUA_1G14290 AFUA_1G14290 LSM8 LSM8 AFUA_1G13890 AFUA_1G13890 AFUA_4G04350 AFUA_4G04350 AFUA_4G04330 AFUA_4G04330 slt11 slt11 AFUA_7G01910 AFUA_7G01910 AFUA_7G02280 AFUA_7G02280 AFUA_8G04960 AFUA_8G04960 AFUA_8G04740 AFUA_8G04740 AFUA_8G04590 AFUA_8G04590 AFUA_8G03990 AFUA_8G03990 AFUA_8G03930 AFUA_8G03930 cyp3 cyp3 cyp1 cyp1 sub2 sub2 AFUA_6G04180 AFUA_6G04180 AFUA_6G05130 AFUA_6G05130 AFUA_6G05180 AFUA_6G05180 fal1 fal1 AFUA_5G02420 AFUA_5G02420 prp45 prp45 AFUA_5G04420 AFUA_5G04420 AFUA_3G02380 AFUA_3G02380 LSM5 LSM5 AFUA_7G05310 AFUA_7G05310 AFUA_7G05980 AFUA_7G05980 AFUA_2G06070 AFUA_2G06070 AFUA_2G05960 AFUA_2G05960 AFUA_2G05950 AFUA_2G05950 cef1 cef1 AFUA_2G05110 AFUA_2G05110 AFUA_2G03260 AFUA_2G03260 AFUA_2G03030 AFUA_2G03030 AFUA_1G07440 AFUA_1G07440 AFUA_1G06460 AFUA_1G06460 AFUA_1G05700 AFUA_1G05700 AFUA_1G03820 AFUA_1G03820 rse1 rse1 AFUA_6G09950 AFUA_6G09950 AFUA_6G07300 AFUA_6G07300 lsm6 lsm6 AFUA_4G06840 AFUA_4G06840 AFUA_4G07520 AFUA_4G07520 AFUA_4G07740 AFUA_4G07740 prp28 prp28 syf2 syf2 AFUA_4G10240 AFUA_4G10240 AFUA_4G10420 AFUA_4G10420 AFUA_4G11880 AFUA_4G11880 AFUA_4G12190 AFUA_4G12190 AFUA_4G13350 AFUA_4G13350 AFUA_1G16990 AFUA_1G16990 AFUA_1G14060 AFUA_1G14060 AFUA_1G10960 AFUA_1G10960 prp46 prp46 AFUA_1G10320 AFUA_1G10320 clf1 clf1 AFUA_1G10190 AFUA_1G10190 prp5 prp5 AFUA_1G09380 AFUA_1G09380 AFUA_5G05610 AFUA_5G05610 AFUA_5G08310 AFUA_5G08310 isy1 isy1 AFUA_5G09060 AFUA_5G09060 AFUA_5G10830 AFUA_5G10830 lea1 lea1 AFUA_5G11620 AFUA_5G11620 syf1 syf1 AFUA_5G12570 AFUA_5G12570 AFUA_5G12910 AFUA_5G12910 AFUA_5G13480 AFUA_5G13480 AFUA_5G13510 AFUA_5G13510 AFUA_5G13860 AFUA_5G13860 AFUA_3G06440 AFUA_3G06440 slu7 slu7 AFUA_3G10450 AFUA_3G10450 AFUA_3G12290 AFUA_3G12290 AFUA_2G15500 AFUA_2G15500 AFUA_2G15210 AFUA_2G15210 AFUA_2G13780 AFUA_2G13780 LSM4 LSM4 dbp2 dbp2 AFUA_2G08870 AFUA_2G08870 AFUA_2G08570 AFUA_2G08570 AFUA_2G07710 AFUA_2G07710
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AFUA_5G07180THO complex component (Rlr1), putative. (2473 aa)
AFUA_1G14290Small nuclear ribonucleoprotein (LSM7), putative. (134 aa)
LSM8U6 snRNA-associated Sm-like protein LSm8; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA. (98 aa)
AFUA_1G13890U4/U6 small nuclear ribonucleoprotein, putative. (590 aa)
AFUA_4G04350Pre-mRNA-splicing factor; Involved in mRNA splicing where it associates with cdc5 and the other cwf proteins as part of the spliceosome. (1418 aa)
AFUA_4G04330THO complex subunit Tho1, putative. (673 aa)
slt11Pre-mRNA-splicing factor slt11; Involved in pre-mRNA splicing. Facilitates the cooperative formation of U2/U6 helix II in association with stem II in the spliceosome. Binds to RNA (By similarity). (383 aa)
AFUA_7G01910DUF1716 domain protein. (585 aa)
AFUA_7G02280U5 snRNP complex subunit, putative. (359 aa)
AFUA_8G04960Small nuclear ribonucleoprotein G. (78 aa)
AFUA_8G04740Pre-mRNA splicing helicase, putative. (2209 aa)
AFUA_8G04590Pre-mRNA splicing factor, putative. (536 aa)
AFUA_8G03990U5 snRNP component Snu114, putative. (985 aa)
AFUA_8G03930Hsp70 chaperone (HscA), putative; Belongs to the heat shock protein 70 family. (614 aa)
cyp3Peptidyl-prolyl cis-trans isomerase H; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity). (181 aa)
cyp1Peptidyl-prolyl cis-trans isomerase-like 1; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity); Belongs to the cyclophilin-type PPIase family. PPIL1 subfamily. (161 aa)
sub2ATP-dependent RNA helicase sub2; ATP-binding RNA helicase involved in transcription elongation and required for the export of mRNA out of the nucleus. SUB2 plays also a role in pre-mRNA splicing and spliceosome assembly. May be involved in rDNA and telomeric silencing, and maintenance of genome integrity (By similarity); Belongs to the DEAD box helicase family. DECD subfamily. (448 aa)
AFUA_6G04180SNRNP27 domain-containing protein. (260 aa)
AFUA_6G05130snRNA cap binding complex subunit (Gcr3), putative. (661 aa)
AFUA_6G05180Splicing factor 3b subunit 4. (352 aa)
fal1ATP-dependent RNA helicase fal1; ATP-dependent RNA helicase involved in 40S ribosomal subunit biogenesis. Required for the processing and cleavage of 35S pre-rRNA at sites A0, A1, and A2, leading to mature 18S rRNA (By similarity). Belongs to the DEAD box helicase family. DDX48/FAL1 subfamily. (398 aa)
AFUA_5G02420Splicing factor 3a subunit 3, putative. (542 aa)
prp45Pre-mRNA-processing protein 45; Involved in pre-mRNA splicing. (579 aa)
AFUA_5G04420Splicing factor 3b, subunit 2, 145kD. (554 aa)
AFUA_3G02380U2 auxiliary factor small subunit, putative. (209 aa)
LSM5U6 snRNA-associated Sm-like protein LSm5; Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA. (83 aa)
AFUA_7G05310U2 snRNP auxiliary factor large subunit; Necessary for the splicing of pre-mRNA. Belongs to the splicing factor SR family. (563 aa)
AFUA_7G05980Small nuclear ribonucleoprotein E; Associated with the spliceosome snRNP U1, U2, U4/U6 and U5. Belongs to the snRNP Sm proteins family. (95 aa)
AFUA_2G06070mRNA splicing factor (Prp1/Zer1), putative. (926 aa)
AFUA_2G05960Pre-mRNA branch site protein p14, putative. (100 aa)
AFUA_2G05950Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family. (126 aa)
cef1Pre-mRNA-splicing factor cef1; Involved in pre-mRNA splicing and cell cycle control. (792 aa)
AFUA_2G05110Small nuclear ribonucleoprotein Sm D1; Involved in pre-mRNA splicing. Binds snRNA U1, U2, U4 and U5 which contain a highly conserved structural motif called the Sm binding site; Belongs to the snRNP core protein family. (120 aa)
AFUA_2G03260RNA binding protein (Rbm8A), putative. (158 aa)
AFUA_2G03030Pre-mRNA splicing factor (Prp8), putative. (3170 aa)
AFUA_1G07440Molecular chaperone Hsp70; Belongs to the heat shock protein 70 family. (638 aa)
AFUA_1G06460BCAS2 family protein. (216 aa)
AFUA_1G05700Splicing factor subunit; Belongs to the SF3B5 family. (89 aa)
AFUA_1G03820mRNA splicing factor RNA helicase (Prp16), putative. (915 aa)
rse1Pre-mRNA-splicing factor rse1; Involved in pre-mRNA splicing and cell cycle control. (1225 aa)
AFUA_6G09950Tudor domain-containing protein. (297 aa)
AFUA_6G07300mRNA splicing factor (Prp17), putative. (580 aa)
lsm6U6 snRNA-associated Sm-like protein LSm6; Component of LSm protein complexes, which are involved in RNA processing and may function in a chaperone-like manner, facilitating the efficient association of RNA processing factors with their substrates. Component of the cytoplasmic LSM1-LSM7 complex, which is thought to be involved in mRNA degradation by activating the decapping step in the 5'-to-3' mRNA decay pathway. Component of the nuclear LSM2- LSM8 complex, which is involved in splicing of nuclear mRNAs. LSM2-LSM8 associates with multiple snRNP complexes containing the U6 snRNA (U4/U6 [...] (80 aa)
AFUA_4G06840G-patch DNA repair protein (Drt111), putative. (534 aa)
AFUA_4G07520SnRNP assembly factor, putative. (614 aa)
AFUA_4G07740Small nuclear ribonucleoprotein SmB, putative. (357 aa)
prp28Pre-mRNA-splicing ATP-dependent RNA helicase prp28; ATP-dependent RNA helicase involved in mRNA splicing. May destabilize the U1/5'-splice site duplex to permit an effective competition for the 5'-splice site by the U6 snRNA, resulting in the switch between U1 and U6 at the 5'-splice site. May also act to unwind the U4/U6 base-pairing interaction in the U4/U6/U5 snRNP, facilitating the first covalent step of splicing (By similarity). (796 aa)
syf2Pre-mRNA-splicing factor syf2; Involved in pre-mRNA splicing. (300 aa)
AFUA_4G10240Small nuclear ribonucleoprotein Sm D3. (116 aa)
AFUA_4G10420DNA binding protein SART-1, putative. (673 aa)
AFUA_4G11880Splicing factor 3a subunit 2, putative. (238 aa)
AFUA_4G12190WD repeat-containing protein. (408 aa)
AFUA_4G13350U1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region. (216 aa)
AFUA_1G16990mRNA splicing factor (Prp18), putative. (372 aa)
AFUA_1G14060C2H2 finger domain protein, putative. (218 aa)
AFUA_1G10960Mago nashi domain protein. (154 aa)
prp46Pre-mRNA-splicing factor prp46; Involved in pre-mRNA splicing and required for cell cycle progression at G2/M. (453 aa)
AFUA_1G10320Formin binding protein (FNB3), putative. (790 aa)
clf1Pre-mRNA-splicing factor clf1; Involved in pre-mRNA splicing and cell cycle progression. Required for the spliceosome assembly and initiation of the DNA replication (By similarity). (676 aa)
AFUA_1G10190Pre-mRNA splicing factor (Prp31), putative. (519 aa)
prp5Pre-mRNA-processing ATP-dependent RNA helicase prp5; ATP-dependent RNA helicase involved spliceosome assembly and in nuclear splicing. Catalyzes an ATP-dependent conformational change of U2 snRNP. Bridges U1 and U2 snRNPs and enables stable U2 snRNP association with intron RNA (By similarity); Belongs to the DEAD box helicase family. DDX46/PRP5 subfamily. (1211 aa)
AFUA_1G09380Uncharacterized protein. (202 aa)
AFUA_5G05610Cell cycle control protein Cwf14/Bud31, putative. (148 aa)
AFUA_5G08310RNA binding protein, putative. (334 aa)
isy1Pre-mRNA-splicing factor isy1; Involved in pre-mRNA splicing. (243 aa)
AFUA_5G09060RNA binding protein, putative. (260 aa)
AFUA_5G10830RNA helicase-like splicing factor (HRH1), putative. (1230 aa)
lea1U2 small nuclear ribonucleoprotein A; Involved in pre-mRNA splicing. (253 aa)
AFUA_5G11620Pre-mRNA splicing factor RNA helicase (Prp43), putative. (767 aa)
syf1Pre-mRNA-splicing factor syf1; Involved in pre-mRNA splicing and cell cycle progression. (839 aa)
AFUA_5G12570U6 small nuclear ribonucleoprotein (Lsm3), putative. (83 aa)
AFUA_5G12910Small nuclear ribonucleoprotein Sm D2. (122 aa)
AFUA_5G13480U1 small nuclear ribonucleoprotein 70 kDa. (395 aa)
AFUA_5G13510Cell cycle control protein (Cwf8), putative. (476 aa)
AFUA_5G13860RNA annealing protein Yra1, putative. (170 aa)
AFUA_3G06440Pre-mRNA splicing factor, putative. (510 aa)
slu7Pre-mRNA-splicing factor slu7; Involved in pre-mRNA splicing. (476 aa)
AFUA_3G10450CID domain-containing protein. (816 aa)
AFUA_3G12290Spliceosomal protein DIB1; Essential role in pre-mRNA splicing. Also essential for entry into mitosis (G2/M progression) as well as for chromosome segregation during mitosis; Belongs to the DIM1 family. (162 aa)
AFUA_2G15500Small nuclear ribonucleoprotein SmF, putative. (88 aa)
AFUA_2G15210U6 snRNA-associated Sm-like protein LSm2; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (91 aa)
AFUA_2G13780Splicing factor 3B subunit 1, putative. (1246 aa)
LSM4U6 snRNA-associated Sm-like protein LSm4; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (119 aa)
dbp2ATP-dependent RNA helicase dbp2; ATP-dependent RNA helicase involved nonsense-mediated mRNA decay and ribosome biogenesis through rRNA processing. (547 aa)
AFUA_2G08870Cell cycle control protein Cwf15, putative. (240 aa)
AFUA_2G08570Nuclear cap-binding protein subunit 2. (184 aa)
AFUA_2G07710mRNA splicing factor RNA helicase (Cdc28), putative. (1120 aa)
Your Current Organism:
Aspergillus fumigatus
NCBI taxonomy Id: 330879
Other names: A. fumigatus Af293, Aspergillus fumigatus Af293
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