STRINGSTRING
AFUA_2G16692 AFUA_2G16692 AFUA_1G11730 AFUA_1G11730 AFUA_6G06900 AFUA_6G06900 AFUA_4G04810 AFUA_4G04810 AFUA_4G04310 AFUA_4G04310 AFUA_4G04100 AFUA_4G04100 AFUA_4G03870 AFUA_4G03870 AFUA_8G03930 AFUA_8G03930 AFUA_6G02370 AFUA_6G02370 AFUA_6G02540 AFUA_6G02540 AFUA_6G04870 AFUA_6G04870 AFUA_5G01860 AFUA_5G01860 AFUA_3G04060 AFUA_3G04060 AFUA_7G03790 AFUA_7G03790 AFUA_7G05580 AFUA_7G05580 AFUA_7G05700 AFUA_7G05700 AFUA_2G05740 AFUA_2G05740 vps27 vps27 AFUA_2G04720 AFUA_2G04720 hse1 hse1 AFUA_2G03650 AFUA_2G03650 AFUA_1G07440 AFUA_1G07440 AFUA_1G06420 AFUA_1G06420 AFUA_1G03460 AFUA_1G03460 cap2 cap2 AFUA_1G02670 AFUA_1G02670 AFUA_1G02540 AFUA_1G02540 AFUA_1G02190 AFUA_1G02190 AFUA_6G14220 AFUA_6G14220 AFUA_6G12570 AFUA_6G12570 cap1 cap1 AFUA_6G07830 AFUA_6G07830 AFUA_6G06500 AFUA_6G06500 AFUA_4G06400 AFUA_4G06400 AFUA_4G07700 AFUA_4G07700 AFUA_4G08040 AFUA_4G08040 AFUA_4G11000 AFUA_4G11000 AFUA_4G12060 AFUA_4G12060 AFUA_4G12290 AFUA_4G12290 AFUA_4G12830 AFUA_4G12830 snx4 snx4 AFUA_1G16320 AFUA_1G16320 AFUA_1G14830 AFUA_1G14830 aps2 aps2 AFUA_1G13960 AFUA_1G13960 hulA hulA AFUA_1G09480 AFUA_1G09480 AFUA_1G09220 AFUA_1G09220 AFUA_5G07130 AFUA_5G07130 AFUA_5G07930 AFUA_5G07930 AFUA_5G11900 AFUA_5G11900 AFUA_5G12130 AFUA_5G12130 AFUA_5G13410 AFUA_5G13410 AFUA_5G13890 AFUA_5G13890 AFUA_3G05630 AFUA_3G05630 AFUA_3G06080 AFUA_3G06080 snx3 snx3 AFUA_3G08730 AFUA_3G08730 AFUA_3G09360 AFUA_3G09360 AFUA_3G10360 AFUA_3G10360 AFUA_3G10700 AFUA_3G10700 AFUA_3G10740 AFUA_3G10740 AFUA_3G12080 AFUA_3G12080 AFUA_3G13770 AFUA_3G13770 AFUA_3G14230 AFUA_3G14230 AFUA_3G14380 AFUA_3G14380 AFUA_2G16520 AFUA_2G16520 AFUA_2G10340 AFUA_2G10340 AFUA_2G09830 AFUA_2G09830
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AFUA_2G16692Vacuolar sorting protein SNF7 family protein, putative. (480 aa)
AFUA_1G11730ADP-ribosylation factor, putative; Belongs to the small GTPase superfamily. Arf family. (183 aa)
AFUA_6G06900Rho GTPase Rho1. (200 aa)
AFUA_4G04810Rab GTPase SrgA, putative. (206 aa)
AFUA_4G04310AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. (939 aa)
AFUA_4G04100Vacuolar protein sorting protein (Vps36), putative. (537 aa)
AFUA_4G03870Vacuolar-sorting protein SNF8; Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. Belongs to the SNF8 family. (260 aa)
AFUA_8G03930Hsp70 chaperone (HscA), putative; Belongs to the heat shock protein 70 family. (614 aa)
AFUA_6G02370Actin-related protein 2/3 complex subunit 4; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament; Belongs to the ARPC4 family. (169 aa)
AFUA_6G02540Actin associated protein Wsp1, putative. (643 aa)
AFUA_6G04870Vacuolar protein sorting-associated protein VpsB; Belongs to the STXBP/unc-18/SEC1 family. (595 aa)
AFUA_5G01860Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (188 aa)
AFUA_3G04060SNF7 family protein Fti1/Did2, putative. (209 aa)
AFUA_7G03790ARF GTPase activator (Csx2), putative. (1111 aa)
AFUA_7G05580Phospholipase. (879 aa)
AFUA_7G05700Guanyl-nucleotide exchange factor (Sec7), putative. (2004 aa)
AFUA_2G05740Rho GTPase ModA, putative. (192 aa)
vps27Vacuolar protein sorting-associated protein 27; Component of the ESCRT-0 complex which is the sorting receptor for ubiquitinated cargo proteins at the multivesicular body (MVB) and recruits ESCRT-I to the MVB outer membrane. (729 aa)
AFUA_2G04720Ubiquitin C-terminal hydrolase, putative. (1108 aa)
hse1Class E vacuolar protein-sorting machinery protein hse1; Component of the ESCRT-0 complex which is the sorting receptor for ubiquitinated cargo proteins at the multivesicular body (MVB). (584 aa)
AFUA_2G03650Golgi to endosome transport protein (Ent3), putative. (550 aa)
AFUA_1G07440Molecular chaperone Hsp70; Belongs to the heat shock protein 70 family. (638 aa)
AFUA_1G06420SNF7 family protein. (241 aa)
AFUA_1G03460Uncharacterized protein. (361 aa)
cap2F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments (By similarity). (322 aa)
AFUA_1G02670Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (320 aa)
AFUA_1G02540EF hand domain protein. (1258 aa)
AFUA_1G02190Ras GTPase Rab11, putative. (204 aa)
AFUA_6G14220Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (929 aa)
AFUA_6G12570EH domain binding protein epsin 2. (561 aa)
cap1F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments (By similarity). (276 aa)
AFUA_6G07830Stromal membrane-associated protein. (604 aa)
AFUA_6G06500Actin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks; Belongs to the WD repeat ARPC1 family. (363 aa)
AFUA_4G06400pH signal transduction protein PalA, putative. (834 aa)
AFUA_4G07700Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1693 aa)
AFUA_4G08040RAB GTPase Ypt5, putative. (218 aa)
AFUA_4G11000SNF7 family protein (Cta1), putative. (216 aa)
AFUA_4G12060Vacuolar protein sorting-associated protein 26, putative. (349 aa)
AFUA_4G12290ESCRT-II complex component (Vps25), putative. (195 aa)
AFUA_4G12830Vacuolar protein sorting-associated protein Vps5, putative. (530 aa)
snx4Sorting nexin-4; Sorting nexin, involved in the separation or division of vacuoles throughout the entire life cycle of the cells. Involved in retrieval of late-Golgi SNAREs from post-Golgi endosomes to the trans- Golgi network, for cytoplasm to vacuole transport (Cvt), mitophagy, and pexophagy (By similarity). (497 aa)
AFUA_1G16320Vacuolar protein sorting-associated protein 28; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process. (244 aa)
AFUA_1G14830Senescence domain-containing protein. (500 aa)
aps2AP-2 complex subunit sigma; Component of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration (By similarity). (145 aa)
AFUA_1G13960DUF292 domian protein. (332 aa)
hulAProbable E3 ubiquitin-protein ligase hulA; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Probably involved in the regulatory network controlling carbon source utilization. (813 aa)
AFUA_1G09480Vacuolar protein sorting-associated protein 29; Belongs to the VPS29 family. (195 aa)
AFUA_1G09220SNF7 family protein. (217 aa)
AFUA_5G07130Zinc finger protein gcs1. (412 aa)
AFUA_5G07930AP-2 adaptor complex subunit mu, putative; Belongs to the adaptor complexes medium subunit family. (445 aa)
AFUA_5G11900Guanine nucleotide exchange factor (Gea2), putative. (1617 aa)
AFUA_5G12130Rab small monomeric GTPase Rab7, putative. (171 aa)
AFUA_5G13410SNF7 family protein. (224 aa)
AFUA_5G13890SNF7 family protein. (229 aa)
AFUA_3G05630Phospholipase. (1807 aa)
AFUA_3G06080Multicopy suppressor of stt4 mutation. (905 aa)
snx3Sorting nexin-3; Required for retention of late Golgi membrane proteins. Component of the retrieval machinery that functions by direct interaction with the cytosolic tails of certain TGN membrane proteins during the sorting/budding process at the prevacuolar compartment. Binds phosphatidylinositol 3-phosphate (PtdIns(P3)) (By similarity). (142 aa)
AFUA_3G08730Endosome-associated ubiquitin isopeptidase (AmsH), putative. (532 aa)
AFUA_3G09360Vacuolar sorting ATPase Vps4, putative; Belongs to the AAA ATPase family. (435 aa)
AFUA_3G10360Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting. (878 aa)
AFUA_3G10700Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (193 aa)
AFUA_3G10740RAB GTPase Vps21/Ypt51, putative. (262 aa)
AFUA_3G12080ADP-ribosylation factor 6, putative; Belongs to the small GTPase superfamily. Arf family. (184 aa)
AFUA_3G13770Vacuolar segregation protein (Pep7), putative. (672 aa)
AFUA_3G14230BAR adaptor protein RVS167, putative. (406 aa)
AFUA_3G14380Endosomal sorting complex protein TSG101, putative. (579 aa)
AFUA_2G16520Phospholipase. (1101 aa)
AFUA_2G10340AP complex subunit beta; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. (718 aa)
AFUA_2G09830ARF GTPase activator (Glo3), putative. (386 aa)
Your Current Organism:
Aspergillus fumigatus
NCBI taxonomy Id: 330879
Other names: A. fumigatus Af293, Aspergillus fumigatus Af293
Server load: low (14%) [HD]