STRINGSTRING
NFIA_105540 NFIA_105540 NFIA_105550 NFIA_105550 NFIA_107070 NFIA_107070 NFIA_107100 NFIA_107100 NFIA_109080 NFIA_109080 NFIA_036960 NFIA_036960 NFIA_010950 NFIA_010950 NFIA_011450 NFIA_011450 NFIA_017170 NFIA_017170 NCS6 NCS6 NFIA_063200 NFIA_063200 NFIA_068180 NFIA_068180 ncs2 ncs2 NFIA_076130 NFIA_076130 NFIA_076780 NFIA_076780 MEF2 MEF2 NFIA_086040 NFIA_086040 NFIA_087580 NFIA_087580 NFIA_050690 NFIA_050690 NFIA_051660 NFIA_051660 NFIA_052750 NFIA_052750 NFIA_052760 NFIA_052760
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NFIA_105540Uncharacterized protein. (333 aa)
NFIA_105550CSL family zinc fnger-containing protein. (84 aa)
NFIA_107070DnaJ domain protein. (197 aa)
NFIA_107100ATP binding L-PSP endoribonuclease family protein, putative. (791 aa)
NFIA_109080Elongator complex protein 1; Component of the RNA polymerase II elongator complex, a multiprotein complex associated with the RNA polymerase II (Pol II) holoenzyme, and which is involved in transcriptional elongation. Belongs to the ELP1/IKA1 family. (1325 aa)
NFIA_036960Elongator complex protein 3; Catalytic tRNA acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. (576 aa)
NFIA_010950Uncharacterized protein. (518 aa)
NFIA_011450Diphthine synthase, putative. (285 aa)
NFIA_017170Methyltransf_11 domain-containing protein. (243 aa)
NCS6Cytoplasmic tRNA 2-thiolation protein 1; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. May also be involved in protein urmylation. (420 aa)
NFIA_063200RNA polymerase II Elongator complex associated protein Kti12, putative. (425 aa)
NFIA_068180Uncharacterized protein. (429 aa)
ncs2Cytoplasmic tRNA 2-thiolation protein 2; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). May act by forming a heterodimer with ncs6 that ligates sulfur from thiocarboxylated urm1 onto the uridine of tRNAs at wobble position. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. May also be involved in protein urmylation. (370 aa)
NFIA_076130PAXNEB protein superfamily. (393 aa)
NFIA_076780Riboflavin aldehyde-forming enzyme. (243 aa)
MEF2Ribosome-releasing factor 2, mitochondrial; Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. Not involved in the GTP-dependent ribosomal translocation step during translation elongation; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily. (921 aa)
NFIA_086040Alpha-tubulin suppressor protein Aats1, putative. (378 aa)
NFIA_0875802-(3-amino-3-carboxypropyl)histidine synthase subunit 1; Required for the first step of diphthamide biosynthesis, the transfer of 3-amino-3-carboxypropyl from S-adenosyl-L-methionine to a histidine residue. Diphthamide is a post-translational modification of histidine which occurs in elongation factor 2. (445 aa)
NFIA_050690Killer toxin sensitivity protein (Iki1), putative. (252 aa)
NFIA_051660RNA polymerase II Elongator subunit, putative. (811 aa)
NFIA_0527502-(3-amino-3-carboxypropyl)histidine synthase subunit 2; Required for the first step in the synthesis of diphthamide, a post-translational modification of histidine which occurs in translation elongation factor 2; Belongs to the DPH1/DPH2 family. DPH2 subfamily. (565 aa)
NFIA_052760Uncharacterized protein. (877 aa)
Your Current Organism:
Aspergillus fischeri
NCBI taxonomy Id: 331117
Other names: A. fischeri NRRL 181, Aspergillus fischeri NRRL 181, Neosartorya fischeri NRRL 181
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