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| | NFIA_102000 | GED domain-containing protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (706 aa) |
| | NFIA_102880 | AP-3 adaptor complex subunit mu, putative; Belongs to the adaptor complexes medium subunit family. (621 aa) |
| | NFIA_103390 | Vacuolar targeting protein Atg24, putative. (497 aa) |
| | NFIA_103500 | Sorting nexin 3. (530 aa) |
| | NFIA_104190 | Vacuolar protein sorting-associated protein 26, putative. (349 aa) |
| | NFIA_106030 | Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (242 aa) |
| | NFIA_106310 | Spap14e8.04 protein. (200 aa) |
| | atg1 | Serine/threonine-protein kinase atg1; Serine/threonine protein kinase involved in the cytoplasm to vacuole transport (Cvt) and found to be essential in autophagy, where it is required for the formation of autophagosomes. Involved in the clearance of protein aggregates which cannot be efficiently cleared by the proteasome. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing [...] (950 aa) |
| | NFIA_108480 | Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1679 aa) |
| | NFIA_109370 | N-glycosyl-transferase. (343 aa) |
| | NFIA_033850 | AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (148 aa) |
| | atg26 | Sterol 3-beta-glucosyltransferase; Probable sterol 3-beta-glucosyltransferase that mediates autophagic degradation of peroxisomes (pexophagy) (By similarity). Also required for cytoplasm to vacuole transport (Cvt) and autophagic degradation of mitochondria (mitophagy) and nuclei (nucleophagy) (By similarity); Belongs to the glycosyltransferase 28 family. (1418 aa) |
| | NFIA_035210 | TBC domain putative. (707 aa) |
| | NFIA_036010 | Golgi to endosome transport protein (Ent3), putative. (559 aa) |
| | NFIA_036790 | BAR domain protein. (435 aa) |
| | NFIA_036820 | Uncharacterized protein. (200 aa) |
| | NFIA_038210 | Mitochondrial fusion protein (Ugo1), putative. (498 aa) |
| | NFIA_039720 | Vacuolar dynamin-like GTPase VpsA, putative; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (698 aa) |
| | NFIA_009740 | Acetylserotonin methytransferase-like protein (ASMTL), putative. (271 aa) |
| | NFIA_010790 | tRNA(His) guanylyltransferase; Adds a GMP to the 5'-end of tRNA(His) after transcription and RNase P cleavage. (291 aa) |
| | NFIA_011470 | AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (145 aa) |
| | NFIA_011910 | Fes/CIP4 homology domain protein. (863 aa) |
| | NFIA_012490 | Uncharacterized protein. (656 aa) |
| | NFIA_013560 | Mitochondrial dynamin GTPase (Msp1), putative; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (919 aa) |
| | NFIA_014550 | Non-specific serine/threonine protein kinase. (1072 aa) |
| | NFIA_016130 | Vacuolar protein sorting-associated protein 29; Belongs to the VPS29 family. (195 aa) |
| | atg8 | Autophagy-related protein 8; Ubiquitin-like modifier involved in autophagosomes formation. With atg4, mediates the delivery of the autophagosomes to the vacuole via the microtubule cytoskeleton. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Participates also in membrane fusion events that take place in the early secretory pathway. Also involved [...] (118 aa) |
| | NFIA_018700 | AP-1 complex subunit gamma. (755 aa) |
| | NFIA_018790 | Serine/threonine protein kinase, putative. (998 aa) |
| | NFIA_019010 | Vacuolar sorting receptor (Mrl1), putative. (331 aa) |
| | NFIA_022080 | UBA/TS-N domain protein. (1303 aa) |
| | NFIA_022710 | GED domain-containing protein. (527 aa) |
| | NFIA_022720 | Uncharacterized protein. (166 aa) |
| | NFIA_064340 | Uncharacterized protein. (566 aa) |
| | NFIA_064880 | Peptidase family M13 protein. (809 aa) |
| | NFIA_065720 | Taz1-interacting factor 1 (TAF1), putative. (1297 aa) |
| | NFIA_066910 | Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting. (884 aa) |
| | NFIA_068160 | AP complex subunit beta; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. (751 aa) |
| | TRM5 | tRNA (guanine(37)-N1)-methyltransferase; Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding; Belongs to the TRM5 / TYW2 family. (479 aa) |
| | NFIA_069120 | PX domain protein. (908 aa) |
| | NFIA_070010 | Uncharacterized protein. (325 aa) |
| | NFIA_070370 | Sorting nexin (Grd19), putative. (142 aa) |
| | NFIA_071110 | Cytoskeleton assembly control protein Sla2, putative. (1143 aa) |
| | NFIA_071850 | Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. (179 aa) |
| | NFIA_028660 | Uncharacterized protein. (189 aa) |
| | NFIA_029070 | AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. (939 aa) |
| | NFIA_029970 | Carboxylic ester hydrolase; Belongs to the tannase family. (588 aa) |
| | NFIA_031010 | GED domain-containing protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (637 aa) |
| | NFIA_096210 | Uncharacterized protein. (241 aa) |
| | vps10 | Vacuolar protein sorting/targeting protein 10; Functions as a sorting receptor in the Golgi compartment required for the intracellular sorting and delivery of soluble vacuolar proteins, like carboxypeptidase Y (CPY) and proteinase A. Executes multiple rounds of sorting by cycling between the late Golgi and a prevacuolar endosome-like compartment (By similarity); Belongs to the VPS10-related sortilin family. (1487 aa) |
| | NFIA_096530 | Dynamin-like GTPase Dnm1, putative; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (800 aa) |
| | NFIA_097720 | PX domain protein. (225 aa) |
| | NFIA_097940 | Autophagy protein Apg6, putative. (541 aa) |
| | NFIA_099420 | Glycosyltransferase family 28, putative. (986 aa) |
| | NFIA_024600 | AP-3 complex subunit delta; Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane. (933 aa) |
| | NFIA_025850 | UDP-glucose,sterol transferase, putative. (823 aa) |
| | NFIA_027990 | Carboxylic ester hydrolase; Belongs to the tannase family. (573 aa) |
| | NFIA_072910 | Dynamin_M domain-containing protein. (132 aa) |
| | NFIA_073720 | UV radiation resistance protein (UVRAG), putative. (619 aa) |
| | mdv1 | Mitochondrial division protein 1; Involved in mitochondrial fission. Acts as an adapter protein required to form mitochondrial fission complexes. Formation of these complexes is required to promote constriction and fission of the mitochondrial compartment at a late step in mitochondrial division (By similarity); Belongs to the WD repeat MDV1/CAF4 family. (658 aa) |
| | NFIA_075170 | Autophagy protein Apg16, putative. (199 aa) |
| | irs4 | Increased rDNA silencing protein 4; Positive regulator of phosphatidylinositol 4,5-bisphosphate turnover and negatively regulates signaling through the cell integrity pathway. Involved in rDNA silencing (By similarity). (513 aa) |
| | atg18 | Autophagy-related protein 18; The PI(3,5)P2 regulatory complex regulates both the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2). Necessary for proper vacuole morphology. Plays an important role in osmotically-induced vacuole fragmentation. Required for cytoplasm to vacuole transport (Cvt) vesicle formation, pexophagy and starvation- induced autophagy. Involved in correct atg9 trafficking to the pre- autophagosomal structure. Might also be involved in premeiotic DNA replication (By similarity). (429 aa) |
| | NFIA_075900 | AP-3 adaptor complex subunit beta, putative. (825 aa) |
| | NFIA_076500 | Rad60-SLD_2 domain-containing protein. (267 aa) |
| | NFIA_077650 | AP-1 adaptor complex subunit mu, putative; Belongs to the adaptor complexes medium subunit family. (427 aa) |
| | NFIA_077680 | UBA/TS-N domain protein. (989 aa) |
| | NFIA_078610 | Phosphatidylinositol 3-kinase VPS34. (902 aa) |
| | NFIA_078750 | Phosphatidylinositol 3,5-bisphosphate-binding protein, putative. (364 aa) |
| | atg3 | Autophagy-related protein 3; E2 conjugating enzyme required for the cytoplasm to vacuole transport (Cvt) and autophagy. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Responsible for the E2-like covalent binding of phosphatidylethanolamine to the C- terminal Gly of atg8. The atg12-atg5 conjugate plays a role of an E3 and promotes the transfer of [...] (353 aa) |
| | NFIA_079360 | AP-2 adaptor complex subunit mu, putative; Belongs to the adaptor complexes medium subunit family. (460 aa) |
| | NFIA_079830 | GTPase activating protein (Gyp2), putative. (1148 aa) |
| | NFIA_080110 | Vacuolar protein sorting-associated protein 17; Plays a role in vesicular protein sorting. Belongs to the VPS17 family. (612 aa) |
| | NFIA_080910 | ENTH domain protein. (610 aa) |
| | NFIA_081510 | Autophagy-related protein 13; Belongs to the ATG13 family. Fungi subfamily. (989 aa) |
| | NFIA_083040 | Autophagy ubiquitin-activating enzyme ApgG, putative. (751 aa) |
| | NFIA_085740 | AP complex subunit beta; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. (710 aa) |
| | NFIA_086830 | UDP-glucoronosyl and UDP-glucosyl transferase, putative. (521 aa) |
| | NFIA_088510 | Mitochondrial fission 1 protein; Has a role in mitochondrial fission. (172 aa) |
| | atg17 | Autophagy-related protein 17; Autophagy-specific protein that functions in response to autophagy-inducing signals as a scaffold to recruit other ATG proteins to organize pre-autophagosomal structure (PAS) formation. Modulates the timing and magnitude of the autophagy response, such as the size of the sequestering vesicles. Plays particularly a role in pexophagy and nucleophagy (By similarity); Belongs to the ATG17 family. (550 aa) |
| | NFIA_089330 | Autophagy protein Atg20, putative. (636 aa) |
| | NFIA_092560 | Sorting nexin Mvp1. (729 aa) |
| | NFIA_049190 | C6 finger domain protein, putative. (727 aa) |
| | NFIA_050280 | ENDO3c domain-containing protein. (473 aa) |
| | NFIA_052340 | CFEM domain protein, putative. (192 aa) |
| | NFIA_052490 | Uncharacterized protein. (120 aa) |
| | atg5 | Autophagy protein 5; Involved in cytoplasm to vacuole transport (Cvt) and autophagic vesicle formation. Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation. Required for selective autophagic degradation of the nucleus (nucleophagy). Also required for mitophagy, which eliminates defective or superfluous mitochondria in order to fulfill cellular energy requirements and prevent excess ROS production. Conjugation with atg12, through a ubiquitin-like conjugating system involving atg7 as an E1- like activating enzyme and atg10 as an E2- [...] (326 aa) |
| | atg12 | Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in cytoplasm to vacuole transport (Cvt), autophagy vesicles formation, mitophagy, and nucleophagy. Conjugation with atg5 through a ubiquitin-like conjugating system involving also atg7 as an E1-like activating enzyme and atg10 as an E2-like conjugating enzyme, is essential for its function. The atg12-atg5 conjugate functions as an E3-like enzyme which is required for lipidation of atg8 and atg8 association to the vesicle membranes (By similarity). (174 aa) |
| | NFIA_056890 | Protein kinase (VPS15), putative. (1620 aa) |
| | NFIA_057410 | Dynamin family protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (852 aa) |
| | atg9 | Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Required for mitophagy. Cycles between the PAS and the cytoplasmic vesicle pool and may participate in supplying membrane for the growing autophagosome. Also involved in endoplasmic reticulum-specific autophagic process and is essential for the survival of cells subjected to severe ER stress. Different machinerie [...] (953 aa) |
| | NFIA_058530 | EH domain binding protein epsin 2. (565 aa) |
| | NFIA_058940 | AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (185 aa) |
| | atg2 | Autophagy-related protein 2; Required for cytoplasm to vacuole transport (Cvt) vesicles and autophagosomes completion and in peroxisome degradation. Belongs to the ATG2 family. (2137 aa) |
| | cpyA | Carboxypeptidase Y homolog A; Vacuolar carboxypeptidase involved in degradation of small peptides. Digests preferentially peptides containing an aliphatic or hydrophobic residue in P1' position, as well as methionine, leucine or phenylalanine in P1 position of ester substrate (By similarity). (543 aa) |
| | NFIA_059900 | CFEM domain protein. (185 aa) |
