(21 nodes) Valine, leucine and isoleucine biosynthesis, and Branched-chain-amino-acid transaminase activity network (Aspergillus fischeri)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

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protein homology

Your Input:
	NFIA_108060	Threonine dehydratase. (588 aa)
	NFIA_109010	Mitochondrial acetolactate synthase small subunit, putative. (327 aa)
	NFIA_109980	Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (411 aa)
	NFIA_041920	Acetolactate synthase. (663 aa)
	NFIA_042060	Dihydroxy-acid dehydratase (Dad). (624 aa)
	NFIA_009550	3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (366 aa)
	NFIA_017400	Dihydroxy-acid dehydratase, putative. (607 aa)
	NFIA_021110	Mitochondrial dihydroxy acid dehydratase, putative. (608 aa)
	NFIA_022950	Branched-chain amino acid aminotransferase. (379 aa)
	NFIA_062600	Dihydroxy-acid dehydratase (Dad). (541 aa)
	NFIA_062770	Ketol-acid reductoisomerase, mitochondrial; Belongs to the ketol-acid reductoisomerase family. (396 aa)
	NFIA_065070	C6 zinc finger domain protein. (659 aa)
	NFIA_066960	Acetolactate synthase. (694 aa)
	NFIA_024970	Uncharacterized protein. (614 aa)
	NFIA_028170	Aminotransferase, class IV, putative. (323 aa)
	NFIA_085800	Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (397 aa)
	NFIA_089370	Mitochondrial dihydroxy acid dehydratase, putative. (651 aa)
	NFIA_091550	Dihydroxy acid dehydratase, putative. (654 aa)
	NFIA_006210	Uncharacterized protein. (395 aa)
	NFIA_057340	Thiamine pyrophosphate enzyme, putative; Belongs to the TPP enzyme family. (583 aa)
	NFIA_059550	3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (368 aa)

Your Current Organism:

Aspergillus fischeri

NCBI taxonomy Id: 331117
Other names: A. fischeri NRRL 181, Aspergillus fischeri NRRL 181, Neosartorya fischeri NRRL 181

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
NFIA_006210	NFIA_009550	A1DKL8	A1D1I2	Uncharacterized protein.	3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.	0.526
NFIA_006210	NFIA_017400	A1DKL8	A1D3P6	Uncharacterized protein.	Dihydroxy-acid dehydratase, putative.	0.583
NFIA_006210	NFIA_021110	A1DKL8	A1D4R0	Uncharacterized protein.	Mitochondrial dihydroxy acid dehydratase, putative.	0.583
NFIA_006210	NFIA_022950	A1DKL8	A1D591	Uncharacterized protein.	Branched-chain amino acid aminotransferase.	0.480
NFIA_006210	NFIA_028170	A1DKL8	A1DD33	Uncharacterized protein.	Aminotransferase, class IV, putative.	0.480
NFIA_006210	NFIA_042060	A1DKL8	A1D0V8	Uncharacterized protein.	Dihydroxy-acid dehydratase (Dad).	0.583
NFIA_006210	NFIA_059550	A1DKL8	A1DP80	Uncharacterized protein.	3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.	0.526
NFIA_006210	NFIA_062600	A1DKL8	A1D5V5	Uncharacterized protein.	Dihydroxy-acid dehydratase (Dad).	0.583
NFIA_006210	NFIA_065070	A1DKL8	A1D6J9	Uncharacterized protein.	C6 zinc finger domain protein.	0.480
NFIA_006210	NFIA_085800	A1DKL8	A1DGW8	Uncharacterized protein.	Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.	0.480
NFIA_006210	NFIA_089370	A1DKL8	A1DHX3	Uncharacterized protein.	Mitochondrial dihydroxy acid dehydratase, putative.	0.583
NFIA_006210	NFIA_091550	A1DKL8	A1DII9	Uncharacterized protein.	Dihydroxy acid dehydratase, putative.	0.583
NFIA_006210	NFIA_109010	A1DKL8	A1CXQ6	Uncharacterized protein.	Mitochondrial acetolactate synthase small subunit, putative.	0.566
NFIA_006210	NFIA_109980	A1DKL8	A1CY02	Uncharacterized protein.	Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.	0.480
NFIA_009550	NFIA_006210	A1D1I2	A1DKL8	3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.	Uncharacterized protein.	0.526
NFIA_009550	NFIA_024970	A1D1I2	A1DC65	3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.	Uncharacterized protein.	0.526
NFIA_009550	NFIA_041920	A1D1I2	A1D0U4	3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.	Acetolactate synthase.	0.953
NFIA_009550	NFIA_057340	A1D1I2	A1DNL4	3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.	Thiamine pyrophosphate enzyme, putative; Belongs to the TPP enzyme family.	0.415
NFIA_009550	NFIA_059550	A1D1I2	A1DP80	3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.	3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.	0.902
NFIA_009550	NFIA_066960	A1D1I2	A1D735	3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.	Acetolactate synthase.	0.952