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NFIA_014450 NFIA_014450 mdm34 mdm34 NFIA_108930 NFIA_108930 mdm12 mdm12 NFIA_013560 NFIA_013560 yme2 yme2 NFIA_062770 NFIA_062770 NFIA_066120 NFIA_066120 NFIA_070310 NFIA_070310 NFIA_070400 NFIA_070400 NFIA_097530 NFIA_097530 NFIA_026740 NFIA_026740 mdmB mdmB PIF1 PIF1 NFIA_073710 NFIA_073710 NFIA_074570 NFIA_074570 NFIA_076410 NFIA_076410 NFIA_079390 NFIA_079390 MEF2 MEF2 NFIA_081050 NFIA_081050 NFIA_085050 NFIA_085050 NFIA_086990 NFIA_086990 mmm1 mmm1 NFIA_054220 NFIA_054220 NFIA_056660 NFIA_056660 NFIA_058870 NFIA_058870
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NFIA_014450Heat shock protein/chaperonin HSP78, putative; Belongs to the ClpA/ClpB family. (797 aa)
mdm34Mitochondrial distribution and morphology protein 34; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. Mdm34 is required for the interaction of the ER-resident membrane protein mmm1 and the outer mitochondrial membrane-resident beta-barrel protein mdm10. (572 aa)
NFIA_108930SAP domain-containing protein. (390 aa)
mdm12Mitochondrial distribution and morphology protein 12; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. Mdm12 is required for the interaction of the ER-resident membrane protein mmm1 and the outer mitochondrial membrane-resident beta-barrel protein mdm10. The mdm12-mmm1 subcomplex functions in the major beta-barrel assembly pat [...] (439 aa)
NFIA_013560Mitochondrial dynamin GTPase (Msp1), putative; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (919 aa)
yme2Mitochondrial escape protein 2; Plays a role in maintaining the mitochondrial genome and in controlling the mtDNA escape. Involved in the regulation of mtDNA nucleotide structure and number. May have a dispensable role in early maturation of pre-rRNA (By similarity); Belongs to the YME2 family. (869 aa)
NFIA_062770Ketol-acid reductoisomerase, mitochondrial; Belongs to the ketol-acid reductoisomerase family. (396 aa)
NFIA_066120DNA ligase. (833 aa)
NFIA_070310Mitochondrial carrier protein (Rim2), putative; Belongs to the mitochondrial carrier (TC 2.A.29) family. (395 aa)
NFIA_070400Ras-GEF domain-containing protein. (513 aa)
NFIA_097530DNA mismatch repair protein Msh1, putative. (1018 aa)
NFIA_026740DEAD/DEAH box helicase, putative. (691 aa)
mdmBMitochondrial distribution and morphology protein 10; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange. mdm10 is involved in the late assembly steps of the general translocase of the mitochondrial outer membrane (TOM complex). Functions in the tom40-specific route of the assembly of outer membrane beta-barrel proteins, including the association of tom40 with the recepto [...] (471 aa)
PIF1ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. (744 aa)
NFIA_073710Uncharacterized protein. (344 aa)
NFIA_074570DNA polymerase gamma. (1109 aa)
NFIA_076410Mitochondrial ATP-dependent RNA helicase Suv3, putative. (776 aa)
NFIA_079390SsDNA binding protein, putative. (149 aa)
MEF2Ribosome-releasing factor 2, mitochondrial; Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. Not involved in the GTP-dependent ribosomal translocation step during translation elongation; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily. (921 aa)
NFIA_081050Mitochondrial inner membrane translocase subunit (TIM17), putative. (154 aa)
NFIA_085050Mitochondrial genome maintenance protein Mgm101, putative. (304 aa)
NFIA_086990Mitochondrial DnaJ chaperone (Mdj1), putative. (543 aa)
mmm1Maintenance of mitochondrial morphology protein 1; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. The mdm12-mmm1 subcomplex functions in the major beta-barrel assembly pathway that is responsible for biogenesis of all outer membrane beta- barrel proteins, and acts in a late step after the SAM complex. The mdm10-mdm12-mmm1 su [...] (496 aa)
NFIA_054220DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family. (1154 aa)
NFIA_056660UV-endonuclease UVE-1. (598 aa)
NFIA_058870Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. (781 aa)
Your Current Organism:
Aspergillus fischeri
NCBI taxonomy Id: 331117
Other names: A. fischeri NRRL 181, Aspergillus fischeri NRRL 181, Neosartorya fischeri NRRL 181
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