SNF7 family protein.

ZZ type zinc finger domain protein.

Uncharacterized protein.

Protein kinase (VPS15), putative.

Uncharacterized protein.

Taz1-interacting factor 1 (TAF1), putative.

Uncharacterized protein.

ZZ type zinc finger domain protein.

Uncharacterized protein.

Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy.

Uncharacterized protein.

Phosphatidylinositol 3-kinase VPS34.

Uncharacterized protein.

Phosphatidylinositol 3,5-bisphosphate-binding protein, putative.

Uncharacterized protein.

Autophagy-related protein 13; Belongs to the ATG13 family. Fungi subfamily.

Uncharacterized protein.

Autophagy ubiquitin-activating enzyme ApgG, putative.

Uncharacterized protein.

Serine/threonine-protein kinase atg1; Serine/threonine protein kinase involved in the cytoplasm to vacuole transport (Cvt) and found to be essential in autophagy, where it is required for the formation of autophagosomes. Involved in the clearance of protein aggregates which cannot be efficiently cleared by the proteasome. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing [...]

Uncharacterized protein.

Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in cytoplasm to vacuole transport (Cvt), autophagy vesicles formation, mitophagy, and nucleophagy. Conjugation with atg5 through a ubiquitin-like conjugating system involving also atg7 as an E1-like activating enzyme and atg10 as an E2-like conjugating enzyme, is essential for its function. The atg12-atg5 conjugate functions as an E3-like enzyme which is required for lipidation of atg8 and atg8 association to the vesicle membranes (By similarity).

Uncharacterized protein.

Autophagy-related protein 3; E2 conjugating enzyme required for the cytoplasm to vacuole transport (Cvt) and autophagy. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Responsible for the E2-like covalent binding of phosphatidylethanolamine to the C- terminal Gly of atg8. The atg12-atg5 conjugate plays a role of an E3 and promotes the transfer of [...]

Uncharacterized protein.

Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Required for mitophagy. Cycles between the PAS and the cytoplasmic vesicle pool and may participate in supplying membrane for the growing autophagosome. Also involved in endoplasmic reticulum-specific autophagic process and is essential for the survival of cells subjected to severe ER stress. Different machinerie [...]

Rab15, 13, 10, 1, 35, 5, and.

BET3 family protein.

Rab15, 13, 10, 1, 35, 5, and.

ADP-ribosylation factor, putative; Belongs to the small GTPase superfamily. Arf family.

Rab15, 13, 10, 1, 35, 5, and.

Rab6.

Rab15, 13, 10, 1, 35, 5, and.

Uncharacterized protein.

Rab15, 13, 10, 1, 35, 5, and.

Vesicle transport v-snare protein vti1homolog, putative.

Rab15, 13, 10, 1, 35, 5, and.

Trafficking protein particle complex subunit BET3.

Rab15, 13, 10, 1, 35, 5, and.

Serine/threonine-protein kinase atg1; Serine/threonine protein kinase involved in the cytoplasm to vacuole transport (Cvt) and found to be essential in autophagy, where it is required for the formation of autophagosomes. Involved in the clearance of protein aggregates which cannot be efficiently cleared by the proteasome. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing [...]