(29 nodes) Pantothenate and CoA biosynthesis network (Aspergillus fischeri)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

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Known Interactions

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experimentally determined

Predicted Interactions

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protein homology

Your Input:
	NFIA_102400	2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (329 aa)
	NFIA_107580	Aldehyde dehydrogenase Ald3, putative; Belongs to the aldehyde dehydrogenase family. (552 aa)
	NFIA_109010	Mitochondrial acetolactate synthase small subunit, putative. (327 aa)
	NFIA_109980	Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (411 aa)
	NFIA_110190	Flavoprotein, putative. (243 aa)
	NFIA_032990	Aldehyde dehydrogenase, putative. (492 aa)
	NFIA_040060	Dephospho-CoA kinase, putative. (272 aa)
	NFIA_041770	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (550 aa)
	NFIA_041920	Acetolactate synthase. (663 aa)
	NFIA_042060	Dihydroxy-acid dehydratase (Dad). (624 aa)
	NFIA_017400	Dihydroxy-acid dehydratase, putative. (607 aa)
	NFIA_021110	Mitochondrial dihydroxy acid dehydratase, putative. (608 aa)
	NFIA_022950	Branched-chain amino acid aminotransferase. (379 aa)
	NFIA_062600	Dihydroxy-acid dehydratase (Dad). (541 aa)
	NFIA_062770	Ketol-acid reductoisomerase, mitochondrial; Belongs to the ketol-acid reductoisomerase family. (396 aa)
	NFIA_066960	Acetolactate synthase. (694 aa)
	NFIA_070020	Phosphopantothenate-cysteine ligase, putative. (410 aa)
	NFIA_070060	Pantothenate kinase, putative. (456 aa)
	NFIA_070880	2-dehydropantoate 2-reductase, putative. (414 aa)
	NFIA_113710	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (493 aa)
	NFIA_029350	4'-phosphopantetheinyl transferase superfamily protein. (151 aa)
	NFIA_095930	Aldehyde dehydrogenase ALDH; Belongs to the aldehyde dehydrogenase family. (504 aa)
	NFIA_076220	Pantoate--beta-alanine ligase. (342 aa)
	NFIA_084210	4'-phosphopantetheinyl transferase NpgA. (357 aa)
	NFIA_085800	Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (397 aa)
	NFIA_089370	Mitochondrial dihydroxy acid dehydratase, putative. (651 aa)
	NFIA_091550	Dihydroxy acid dehydratase, putative. (654 aa)
	NFIA_054860	3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate. (355 aa)
	NFIA_057120	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (497 aa)

Your Current Organism:

Aspergillus fischeri

NCBI taxonomy Id: 331117
Other names: A. fischeri NRRL 181, Aspergillus fischeri NRRL 181, Neosartorya fischeri NRRL 181

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
NFIA_017400	NFIA_022950	A1D3P6	A1D591	Dihydroxy-acid dehydratase, putative.	Branched-chain amino acid aminotransferase.	0.962
NFIA_017400	NFIA_041920	A1D3P6	A1D0U4	Dihydroxy-acid dehydratase, putative.	Acetolactate synthase.	0.568
NFIA_017400	NFIA_054860	A1D3P6	A1DMW7	Dihydroxy-acid dehydratase, putative.	3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate.	0.920
NFIA_017400	NFIA_062770	A1D3P6	A1D5X2	Dihydroxy-acid dehydratase, putative.	Ketol-acid reductoisomerase, mitochondrial; Belongs to the ketol-acid reductoisomerase family.	0.929
NFIA_017400	NFIA_066960	A1D3P6	A1D735	Dihydroxy-acid dehydratase, putative.	Acetolactate synthase.	0.570
NFIA_017400	NFIA_085800	A1D3P6	A1DGW8	Dihydroxy-acid dehydratase, putative.	Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.	0.962
NFIA_017400	NFIA_109010	A1D3P6	A1CXQ6	Dihydroxy-acid dehydratase, putative.	Mitochondrial acetolactate synthase small subunit, putative.	0.581
NFIA_017400	NFIA_109980	A1D3P6	A1CY02	Dihydroxy-acid dehydratase, putative.	Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.	0.962
NFIA_021110	NFIA_022950	A1D4R0	A1D591	Mitochondrial dihydroxy acid dehydratase, putative.	Branched-chain amino acid aminotransferase.	0.962
NFIA_021110	NFIA_041920	A1D4R0	A1D0U4	Mitochondrial dihydroxy acid dehydratase, putative.	Acetolactate synthase.	0.698
NFIA_021110	NFIA_054860	A1D4R0	A1DMW7	Mitochondrial dihydroxy acid dehydratase, putative.	3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate.	0.920
NFIA_021110	NFIA_062770	A1D4R0	A1D5X2	Mitochondrial dihydroxy acid dehydratase, putative.	Ketol-acid reductoisomerase, mitochondrial; Belongs to the ketol-acid reductoisomerase family.	0.953
NFIA_021110	NFIA_066960	A1D4R0	A1D735	Mitochondrial dihydroxy acid dehydratase, putative.	Acetolactate synthase.	0.700
NFIA_021110	NFIA_085800	A1D4R0	A1DGW8	Mitochondrial dihydroxy acid dehydratase, putative.	Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.	0.962
NFIA_021110	NFIA_109010	A1D4R0	A1CXQ6	Mitochondrial dihydroxy acid dehydratase, putative.	Mitochondrial acetolactate synthase small subunit, putative.	0.607
NFIA_021110	NFIA_109980	A1D4R0	A1CY02	Mitochondrial dihydroxy acid dehydratase, putative.	Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.	0.966
NFIA_022950	NFIA_017400	A1D591	A1D3P6	Branched-chain amino acid aminotransferase.	Dihydroxy-acid dehydratase, putative.	0.962
NFIA_022950	NFIA_021110	A1D591	A1D4R0	Branched-chain amino acid aminotransferase.	Mitochondrial dihydroxy acid dehydratase, putative.	0.962
NFIA_022950	NFIA_041920	A1D591	A1D0U4	Branched-chain amino acid aminotransferase.	Acetolactate synthase.	0.570
NFIA_022950	NFIA_042060	A1D591	A1D0V8	Branched-chain amino acid aminotransferase.	Dihydroxy-acid dehydratase (Dad).	0.962