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NFIA_043390 NFIA_043390 NFIA_043700 NFIA_043700 NFIA_043890 NFIA_043890 NFIA_044540 NFIA_044540 NFIA_103240 NFIA_103240 NFIA_104260 NFIA_104260 NFIA_105160 NFIA_105160 NFIA_105250 NFIA_105250 NFIA_105300 NFIA_105300 NFIA_105610 NFIA_105610 NFIA_105660 NFIA_105660 NFIA_107400 NFIA_107400 NFIA_108060 NFIA_108060 NFIA_108360 NFIA_108360 NFIA_108470 NFIA_108470 NFIA_108860 NFIA_108860 NFIA_109010 NFIA_109010 NFIA_109030 NFIA_109030 NFIA_109340 NFIA_109340 NFIA_109720 NFIA_109720 NFIA_109980 NFIA_109980 NFIA_032250 NFIA_032250 NFIA_036940 NFIA_036940 NFIA_037310 NFIA_037310 NFIA_037460 NFIA_037460 NFIA_037560 NFIA_037560 NFIA_037850 NFIA_037850 NFIA_037870 NFIA_037870 NFIA_039870 NFIA_039870 NFIA_039930 NFIA_039930 NFIA_040150 NFIA_040150 NFIA_041130 NFIA_041130 NFIA_041920 NFIA_041920 NFIA_042060 NFIA_042060 NFIA_007520 NFIA_007520 NFIA_009550 NFIA_009550 NFIA_010410 NFIA_010410 NFIA_010850 NFIA_010850 NFIA_011330 NFIA_011330 aroM aroM NFIA_012000 NFIA_012000 NFIA_012430 NFIA_012430 NFIA_012760 NFIA_012760 qutE1 qutE1 NFIA_014260 NFIA_014260 NFIA_015020 NFIA_015020 NFIA_015330 NFIA_015330 NFIA_017350 NFIA_017350 NFIA_017400 NFIA_017400 NFIA_017750 NFIA_017750 NFIA_017880 NFIA_017880 NFIA_018580 NFIA_018580 NFIA_020570 NFIA_020570 NFIA_021110 NFIA_021110 NFIA_022540 NFIA_022540 NFIA_022950 NFIA_022950 qutE2 qutE2 NFIA_062600 NFIA_062600 NFIA_062770 NFIA_062770 NFIA_062780 NFIA_062780 NFIA_063980 NFIA_063980 NFIA_065620 NFIA_065620 NFIA_065640 NFIA_065640 NFIA_065670 NFIA_065670 NFIA_065870 NFIA_065870 NFIA_066960 NFIA_066960 NFIA_067820 NFIA_067820 NFIA_067840 NFIA_067840 NFIA_068150 NFIA_068150 NFIA_068460 NFIA_068460 NFIA_069370 NFIA_069370 NFIA_070420 NFIA_070420 NFIA_070710 NFIA_070710 NFIA_071710 NFIA_071710 NFIA_029360 NFIA_029360 NFIA_029440 NFIA_029440 NFIA_029700 NFIA_029700 NFIA_096280 NFIA_096280 NFIA_097070 NFIA_097070 NFIA_097960 NFIA_097960 NFIA_025030 NFIA_025030 NFIA_025470 NFIA_025470 NFIA_026920 NFIA_026920 NFIA_027830 NFIA_027830 NFIA_072200 NFIA_072200 NFIA_073610 NFIA_073610 NFIA_073900 NFIA_073900 NFIA_076970 NFIA_076970 NFIA_078100 NFIA_078100 NFIA_078420 NFIA_078420 NFIA_079180 NFIA_079180 NFIA_080050 NFIA_080050 NFIA_081090 NFIA_081090 NFIA_081250 NFIA_081250 NFIA_083020 NFIA_083020 NFIA_083130 NFIA_083130 NFIA_083310 NFIA_083310 NFIA_083350 NFIA_083350 NFIA_083520 NFIA_083520 NFIA_085130 NFIA_085130 NFIA_085800 NFIA_085800 NFIA_085830 NFIA_085830 NFIA_086320 NFIA_086320 NFIA_086330 NFIA_086330 NFIA_086540 NFIA_086540 arg2 arg2 NFIA_087610 NFIA_087610 NFIA_088420 NFIA_088420 NFIA_088830 NFIA_088830 NFIA_089370 NFIA_089370 NFIA_090170 NFIA_090170 NFIA_090440 NFIA_090440 NFIA_090540 NFIA_090540 NFIA_090620 NFIA_090620 NFIA_091550 NFIA_091550 NFIA_003470 NFIA_003470 NFIA_048770 NFIA_048770 NFIA_049240 NFIA_049240 NFIA_049580 NFIA_049580 NFIA_050040 NFIA_050040 NFIA_050100 NFIA_050100 NFIA_051240 NFIA_051240 NFIA_051530 NFIA_051530 NFIA_052000 NFIA_052000 NFIA_052420 NFIA_052420 NFIA_052450 NFIA_052450 NFIA_053070 NFIA_053070 NFIA_053110 NFIA_053110 NFIA_053440 NFIA_053440 NFIA_055160 NFIA_055160 NFIA_056380 NFIA_056380 NFIA_058540 NFIA_058540 NFIA_058870 NFIA_058870 NFIA_059480 NFIA_059480 NFIA_059550 NFIA_059550 NFIA_060300 NFIA_060300 NFIA_060590 NFIA_060590
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NFIA_043390Aspartate aminotransferase. (368 aa)
NFIA_043700Phospho-2-dehydro-3-deoxyheptonate aldolase. (391 aa)
NFIA_043890Homocysteine synthase, putative. (429 aa)
NFIA_044540ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (791 aa)
NFIA_103240Glutamine synthetase. (358 aa)
NFIA_104260Anthranilate phosphoribosyltransferase, putative. (429 aa)
NFIA_105160Alpha-aminoadipate reductase large subunit, putative. (1425 aa)
NFIA_105250Saccharopine dehydrogenase. (450 aa)
NFIA_105300Phosphoribosyl diphosphate synthase isoform 4. (320 aa)
NFIA_105610Homocitrate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. (463 aa)
NFIA_105660Aspartate aminotransferase. (429 aa)
NFIA_107400Phospho-2-dehydro-3-deoxyheptonate aldolase; Belongs to the class-II DAHP synthase family. (462 aa)
NFIA_108060Threonine dehydratase. (588 aa)
NFIA_108360L-serine dehydratase. (464 aa)
NFIA_108470Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1193 aa)
NFIA_1088605-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase. (774 aa)
NFIA_109010Mitochondrial acetolactate synthase small subunit, putative. (327 aa)
NFIA_109030Ornithine carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. (371 aa)
NFIA_109340Asparagine synthetase Asn2, putative. (573 aa)
NFIA_109720Pentafunctional AROM polypeptide, putative. (712 aa)
NFIA_109980Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (411 aa)
NFIA_032250Aspartate aminotransferase. (276 aa)
NFIA_0369401-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase. (256 aa)
NFIA_037310Homoserine kinase. (355 aa)
NFIA_037460Aspartokinase. (484 aa)
NFIA_037560D-3-phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (472 aa)
NFIA_037850Homocysteine synthase CysD. (436 aa)
NFIA_037870Citrate synthase; Belongs to the citrate synthase family. (474 aa)
NFIA_039870NAD dependent epimerase/dehydratase family protein. (314 aa)
NFIA_039930Cysteine synthase (O-acetylserine (Thiol)-lyase) (Csase). (371 aa)
NFIA_040150Glyceraldehyde-3-phosphate dehydrogenase. (338 aa)
NFIA_041130Glyceraldehyde-3-phosphate dehydrogenase. (337 aa)
NFIA_041920Acetolactate synthase. (663 aa)
NFIA_042060Dihydroxy-acid dehydratase (Dad). (624 aa)
NFIA_007520Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (437 aa)
NFIA_0095503-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (366 aa)
NFIA_0104102-isopropylmalate synthase. (643 aa)
NFIA_010850Histidine biosynthesis trifunctional protein. (872 aa)
NFIA_011330Histidinol-phosphate aminotransferase. (440 aa)
aroM3-phosphoshikimate 1-carboxyvinyltransferase; The AROM polypeptide catalyzes 5 consecutive enzymatic reactions in prechorismate polyaromatic amino acid biosynthesis. In the N-terminal section; belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. In the 3rd section; belongs to the shikimate kinase family. In the C-terminal section; belongs to the shikimate dehydrogenase family. (1578 aa)
NFIA_012000Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (684 aa)
NFIA_012430Multifunctional tryptophan biosynthesis protein; Trifunctional enzyme bearing the Gln amidotransferase (GATase) domain of anthranilate synthase, indole-glycerolphosphate synthase, and phosphoribosylanthranilate isomerase activities. (762 aa)
NFIA_012760Isocitrate dehydrogenase [NAD] subunit, mitochondrial. (385 aa)
qutE1Catabolic 3-dehydroquinase 1; Is involved in the catabolism of quinate. Allows the utilization of quinate as carbon source via the beta-ketoadipate pathway; Belongs to the type-II 3-dehydroquinase family. (150 aa)
NFIA_014260Phospho-2-dehydro-3-deoxyheptonate aldolase; Belongs to the class-II DAHP synthase family. (453 aa)
NFIA_015020S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. (387 aa)
NFIA_015330Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (417 aa)
NFIA_017350Glutamate synthase Glt1, putative. (2126 aa)
NFIA_017400Dihydroxy-acid dehydratase, putative. (607 aa)
NFIA_017750Chorismate synthase. (412 aa)
NFIA_017880Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. (799 aa)
NFIA_018580L-serine dehydratase, putative. (361 aa)
NFIA_020570Aspartate aminotransferase, putative. (444 aa)
NFIA_021110Mitochondrial dihydroxy acid dehydratase, putative. (608 aa)
NFIA_022540Phospho-2-dehydro-3-deoxyheptonate aldolase. (376 aa)
NFIA_022950Branched-chain amino acid aminotransferase. (379 aa)
qutE2Catabolic 3-dehydroquinase 2; Is involved in the catabolism of quinate. Allows the utilization of quinate as carbon source via the beta-ketoadipate pathway; Belongs to the type-II 3-dehydroquinase family. (150 aa)
NFIA_062600Dihydroxy-acid dehydratase (Dad). (541 aa)
NFIA_062770Ketol-acid reductoisomerase, mitochondrial; Belongs to the ketol-acid reductoisomerase family. (396 aa)
NFIA_062780Pyridoxal-phosphate dependent enzyme, putative. (385 aa)
NFIA_063980Ribose-phosphate pyrophosphokinase. (436 aa)
NFIA_065620Saccharopine dehydrogenase [NAD(+), L-lysine-forming]; Belongs to the AlaDH/PNT family. (374 aa)
NFIA_065640Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (360 aa)
NFIA_065670Homoserine dehydrogenase. (368 aa)
NFIA_065870Arginase; Belongs to the arginase family. (324 aa)
NFIA_066960Acetolactate synthase. (694 aa)
NFIA_067820Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (471 aa)
NFIA_067840Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent. (520 aa)
NFIA_068150Threonine synthase. (536 aa)
NFIA_068460Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (413 aa)
NFIA_069370Argininosuccinate lyase. (464 aa)
NFIA_070420Aspartate-semialdehyde dehydrogenase. (363 aa)
NFIA_070710Phosphoserine phosphatase. (469 aa)
NFIA_071710Cystathionine gamma-synthase. (601 aa)
NFIA_029360Histidinol-phosphatase; Belongs to the PHP hydrolase family. HisK subfamily. (308 aa)
NFIA_029440Cystathionine beta-lyase MetG. (443 aa)
NFIA_029700Glutamine synthetase bacteria; Belongs to the glutamine synthetase family. (479 aa)
NFIA_096280Glyceraldehyde-3-phosphate dehydrogenase, putative; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (379 aa)
NFIA_097070Cystathionine gamma-lyase. (412 aa)
NFIA_097960Cysteine synthase, putative. (417 aa)
NFIA_025030Phospho-2-dehydro-3-deoxyheptonate aldolase. (369 aa)
NFIA_025470ATP phosphoribosyltransferase. (303 aa)
NFIA_026920Ribose phosphate diphosphokinase Prs1, putative. (483 aa)
NFIA_027830Threonine aldolase, putative. (360 aa)
NFIA_072200Pyrroline-5-carboxylate reductase; Belongs to the pyrroline-5-carboxylate reductase family. (284 aa)
NFIA_073610Triosephosphate isomerase. (249 aa)
NFIA_073900Chorismate mutase. (266 aa)
NFIA_076970Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (284 aa)
NFIA_078100Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. (324 aa)
NFIA_078420Homoaconitase, mitochondrial; Catalyzes the reversible hydration of cis-homoaconitate to (2R,3S)-homoisocitrate, a step in the alpha-aminoadipate pathway for lysine biosynthesis. (777 aa)
NFIA_079180Arginine biosynthesis bifunctional protein ArgJ, mitochondrial; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate. (456 aa)
NFIA_080050Homoserine O-acetyltransferase, putative. (491 aa)
NFIA_081090Argininosuccinate synthase. (416 aa)
NFIA_081250D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (582 aa)
NFIA_083020Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family. (550 aa)
NFIA_083130Glutamate semialdehyde dehydrogenase. (456 aa)
NFIA_083310Glutamate 5-kinase, putative. (359 aa)
NFIA_083350Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (534 aa)
NFIA_083520Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (537 aa)
NFIA_085130Aspartate transaminase, putative. (462 aa)
NFIA_085800Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (397 aa)
NFIA_085830Prephenate dehydrogenase [NADP(+)]; Belongs to the prephenate/arogenate dehydrogenase family. (434 aa)
NFIA_086320Triosephosphate isomerase. (285 aa)
NFIA_086330Ribose/galactose isomerase, putative. (162 aa)
NFIA_0865403-isopropylmalate dehydratase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (777 aa)
arg2Amino-acid acetyltransferase, mitochondrial; N-acetylglutamate synthase involved in arginine biosynthesis. Belongs to the acetyltransferase family. (716 aa)
NFIA_087610Acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (485 aa)
NFIA_088420Tryptophan synthase. (722 aa)
NFIA_088830Aromatic aminotransferase Aro8, putative. (526 aa)
NFIA_089370Mitochondrial dihydroxy acid dehydratase, putative. (651 aa)
NFIA_090170L-allo-threonine aldolase. (394 aa)
NFIA_090440Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (252 aa)
NFIA_090540Citrate synthase; Belongs to the citrate synthase family. (433 aa)
NFIA_090620FluG family protein; Belongs to the glutamine synthetase family. (447 aa)
NFIA_091550Dihydroxy acid dehydratase, putative. (654 aa)
NFIA_003470Pyrroline-5-carboxylate reductase. (280 aa)
NFIA_048770Aspartate aminotransferase. (412 aa)
NFIA_049240Acetylglutamate kinase, putative; In the N-terminal section; belongs to the acetylglutamate kinase family. (906 aa)
NFIA_049580Tryptophan synthase. (689 aa)
NFIA_050040Glutamine synthetase; Belongs to the glutamine synthetase family. (488 aa)
NFIA_050100Citrate synthase; Belongs to the citrate synthase family. (465 aa)
NFIA_051240Imidazoleglycerol-phosphate dehydratase. (244 aa)
NFIA_051530Phosphoserine aminotransferase. (428 aa)
NFIA_052000Isocitrate dehydrogenase [NAD] subunit, mitochondrial. (386 aa)
NFIA_052420Enolase/allergen Asp F 22. (438 aa)
NFIA_052450Probable carboxypeptidase NFIA_052450; Belongs to the peptidase M20A family. (441 aa)
NFIA_053070Isocitrate dehydrogenase LysB. (359 aa)
NFIA_053110Pyruvate kinase; Belongs to the pyruvate kinase family. (527 aa)
NFIA_053440Alanine aminotransferase, putative. (495 aa)
NFIA_055160Tryptophan synthase. (456 aa)
NFIA_056380Ribose 5-phosphate isomerase A. (272 aa)
NFIA_058540Anthranilate synthase component I, putative. (513 aa)
NFIA_058870Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. (781 aa)
NFIA_059480Tryptophan synthase. (460 aa)
NFIA_0595503-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (368 aa)
NFIA_060300L-allo-threonine aldolase. (369 aa)
NFIA_060590Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (685 aa)
Your Current Organism:
Aspergillus fischeri
NCBI taxonomy Id: 331117
Other names: A. fischeri NRRL 181, Aspergillus fischeri NRRL 181, Neosartorya fischeri NRRL 181
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