(37 nodes) Spliceosomal tri-snRNP complex network (Hirundo rustica)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LSM4	U6 snRNA-associated Sm-like protein LSm4; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (160 aa)
	DUI87_33030	Uncharacterized protein. (961 aa)
	DUI87_32625	Small nuclear ribonucleoprotein G. (76 aa)
	DUI87_32643	SEC63 domain-containing protein. (329 aa)
	DUI87_32648	SEC63 domain-containing protein. (271 aa)
	DUI87_31685	WD_REPEATS_REGION domain-containing protein. (372 aa)
	DUI87_31681	WD_REPEATS_REGION domain-containing protein. (1293 aa)
	DUI87_32079	Uncharacterized protein. (592 aa)
	DUI87_32988	PWI domain-containing protein. (695 aa)
	DUI87_30239	WD_REPEATS_REGION domain-containing protein. (529 aa)
	DUI87_32651	Helicase ATP-binding domain-containing protein. (859 aa)
	DUI87_32647	Helicase ATP-binding domain-containing protein. (717 aa)
	DUI87_27901	Uncharacterized protein. (145 aa)
	DUI87_26358	Integrase catalytic domain-containing protein. (283 aa)
	DUI87_26949	U1-type domain-containing protein. (221 aa)
	LSM3	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (115 aa)
	DUI87_23953	Small nuclear ribonucleoprotein E; Associated with the spliceosome snRNP U1, U2, U4/U6 and U5. Belongs to the snRNP Sm proteins family. (92 aa)
	DUI87_22450	Sm domain-containing protein. (115 aa)
	DUI87_27900	Uncharacterized protein. (941 aa)
	DUI87_22042	Tr-type G domain-containing protein. (960 aa)
	DUI87_20578	Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family. (128 aa)
	DUI87_20611	Sm domain-containing protein. (91 aa)
	DUI87_18527	Small nuclear ribonucleoprotein Sm D1; Essential for pre-mRNA splicing. Implicated in the formation of stable, biologically active snRNP structures. Belongs to the snRNP core protein family. (96 aa)
	DUI87_17551	Small nuclear ribonucleoprotein Sm D3. (126 aa)
	LSM8	U6 snRNA-associated Sm-like protein LSm8; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA. (96 aa)
	DUI87_12473	MPN domain-containing protein. (2333 aa)
	DUI87_11043	Uncharacterized protein. (149 aa)
	DUI87_13259	SFM domain-containing protein. (342 aa)
	DUI87_08781	Nop domain-containing protein. (216 aa)
	DUI87_09457	Uncharacterized protein. (203 aa)
	DUI87_07131	PRP3 domain-containing protein. (324 aa)
	DUI87_07132	PWI domain-containing protein. (73 aa)
	DUI87_10778	Prp31_C domain-containing protein. (322 aa)
	DUI87_08504	Thioredoxin-like protein; Plays role in pre-mRNA splicing. Belongs to the DIM1 family. (142 aa)
	DUI87_00252	Uncharacterized protein. (571 aa)
	DUI87_00139	Uncharacterized protein. (472 aa)
	DUI87_00115	Small nuclear ribonucleoprotein Sm D2. (139 aa)

Your Current Organism:

Hirundo rustica

NCBI taxonomy Id: 333673
Other names: H. rustica rustica, Hirundo rustica rustica

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DUI87_00115	DUI87_00139	A0A3M0LFU3	A0A3M0LBQ5	Small nuclear ribonucleoprotein Sm D2.	Uncharacterized protein.	0.953
DUI87_00115	DUI87_00252	A0A3M0LFU3	A0A3M0LB63	Small nuclear ribonucleoprotein Sm D2.	Uncharacterized protein.	0.953
DUI87_00115	DUI87_07131	A0A3M0LFU3	A0A3M0KNZ8	Small nuclear ribonucleoprotein Sm D2.	PRP3 domain-containing protein.	0.949
DUI87_00115	DUI87_07132	A0A3M0LFU3	A0A3M0KPF5	Small nuclear ribonucleoprotein Sm D2.	PWI domain-containing protein.	0.949
DUI87_00115	DUI87_08504	A0A3M0LFU3	A0A3M0KSL0	Small nuclear ribonucleoprotein Sm D2.	Thioredoxin-like protein; Plays role in pre-mRNA splicing. Belongs to the DIM1 family.	0.983
DUI87_00115	DUI87_08781	A0A3M0LFU3	A0A3M0KKT5	Small nuclear ribonucleoprotein Sm D2.	Nop domain-containing protein.	0.963
DUI87_00115	DUI87_09457	A0A3M0LFU3	A0A3M0KM96	Small nuclear ribonucleoprotein Sm D2.	Uncharacterized protein.	0.869
DUI87_00115	DUI87_10778	A0A3M0LFU3	A0A3M0KPM9	Small nuclear ribonucleoprotein Sm D2.	Prp31_C domain-containing protein.	0.963
DUI87_00115	DUI87_11043	A0A3M0LFU3	A0A3M0KFJ2	Small nuclear ribonucleoprotein Sm D2.	Uncharacterized protein.	0.975
DUI87_00115	DUI87_12473	A0A3M0LFU3	A0A3M0KE01	Small nuclear ribonucleoprotein Sm D2.	MPN domain-containing protein.	0.999
DUI87_00115	DUI87_13259	A0A3M0LFU3	A0A3M0KGT0	Small nuclear ribonucleoprotein Sm D2.	SFM domain-containing protein.	0.869
DUI87_00115	DUI87_17551	A0A3M0LFU3	A0A3M0JYE3	Small nuclear ribonucleoprotein Sm D2.	Small nuclear ribonucleoprotein Sm D3.	0.999
DUI87_00115	DUI87_18527	A0A3M0LFU3	A0A3M0JX46	Small nuclear ribonucleoprotein Sm D2.	Small nuclear ribonucleoprotein Sm D1; Essential for pre-mRNA splicing. Implicated in the formation of stable, biologically active snRNP structures. Belongs to the snRNP core protein family.	0.999
DUI87_00115	DUI87_20578	A0A3M0LFU3	A0A3M0JT51	Small nuclear ribonucleoprotein Sm D2.	Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family.	0.989
DUI87_00115	DUI87_20611	A0A3M0LFU3	A0A3M0JW77	Small nuclear ribonucleoprotein Sm D2.	Sm domain-containing protein.	0.999
DUI87_00115	DUI87_22042	A0A3M0LFU3	A0A3M0JMS0	Small nuclear ribonucleoprotein Sm D2.	Tr-type G domain-containing protein.	0.999
DUI87_00115	DUI87_22450	A0A3M0LFU3	A0A3M0JIF0	Small nuclear ribonucleoprotein Sm D2.	Sm domain-containing protein.	0.998
DUI87_00115	DUI87_23953	A0A3M0LFU3	A0A3M0JFX2	Small nuclear ribonucleoprotein Sm D2.	Small nuclear ribonucleoprotein E; Associated with the spliceosome snRNP U1, U2, U4/U6 and U5. Belongs to the snRNP Sm proteins family.	0.999
DUI87_00115	DUI87_26358	A0A3M0LFU3	A0A3M0J846	Small nuclear ribonucleoprotein Sm D2.	Integrase catalytic domain-containing protein.	0.997
DUI87_00115	DUI87_26949	A0A3M0LFU3	A0A3M0J9E6	Small nuclear ribonucleoprotein Sm D2.	U1-type domain-containing protein.	0.957