(59 nodes) APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 network (Hirundo rustica)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DUI87_14407	MPN domain-containing protein. (295 aa)
	DUI87_11133	Uncharacterized protein. (121 aa)
	DUI87_09751	Proteasome subunit alpha type. (271 aa)
	DUI87_08768	Anaphase-promoting complex subunit 10; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. (185 aa)
	DUI87_13170	AAA domain-containing protein; Belongs to the AAA ATPase family. (416 aa)
	DUI87_06560	F-box domain-containing protein. (370 aa)
	DUI87_35402	Proteasome subunit beta. (233 aa)
	DUI87_33829	KxDL domain-containing protein. (176 aa)
	DUI87_32380	Proteasome subunit beta. (201 aa)
	DUI87_00237	VWFA domain-containing protein. (449 aa)
	DUI87_09358	Uncharacterized protein. (663 aa)
	DUI87_10232	Uncharacterized protein. (137 aa)
	DUI87_05152	Serine/threonine-protein kinase PLK. (725 aa)
	DUI87_15490	Ubiquitin-like domain-containing protein. (156 aa)
	DUI87_17307	ANAPC5 domain-containing protein. (737 aa)
	DUI87_21815	Proteasome subunit beta. (239 aa)
	DUI87_16595	Uncharacterized protein. (903 aa)
	DUI87_24183	Proteasome subunit alpha type. (241 aa)
	DUI87_18645	Proteasome subunit alpha type. (182 aa)
	DUI87_24802	Proteasome subunit alpha type. (255 aa)
	DUI87_21828	Proteasome subunit beta. (202 aa)
	DUI87_22065	PCI domain-containing protein. (422 aa)
	DUI87_20019	DUF4203 domain-containing protein. (563 aa)
	DUI87_21217	RPN2_C domain-containing protein. (337 aa)
	DUI87_21941	Uncharacterized protein. (254 aa)
	DUI87_28173	RING-type domain-containing protein. (84 aa)
	DUI87_22483	WD_REPEATS_REGION domain-containing protein. (472 aa)
	DUI87_25042	AAA domain-containing protein; Belongs to the AAA ATPase family. (440 aa)
	DUI87_23189	Proteasome endopeptidase complex. (291 aa)
	DUI87_22923	AAA domain-containing protein; Belongs to the AAA ATPase family. (422 aa)
	DUI87_24519	PCI domain-containing protein. (389 aa)
	DUI87_25296	ANK_REP_REGION domain-containing protein. (226 aa)
	DUI87_26886	Uncharacterized protein. (217 aa)
	DUI87_24751	AAA domain-containing protein. (342 aa)
	DUI87_25422	PCI domain-containing protein. (393 aa)
	DUI87_27943	Proteasome subunit alpha type. (248 aa)
	DUI87_28290	PCI domain-containing protein. (386 aa)
	DUI87_26588	TPR_REGION domain-containing protein. (581 aa)
	DUI87_27996	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (413 aa)
	DUI87_27817	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (179 aa)
	DUI87_27870	Uncharacterized protein. (268 aa)
	DUI87_29993	Proteasome subunit beta. (277 aa)
	DUI87_29415	Proteasome subunit alpha type. (261 aa)
	DUI87_28746	Uncharacterized protein. (1035 aa)
	DUI87_28462	AAA domain-containing protein; Belongs to the AAA ATPase family. (377 aa)
	DUI87_30238	Uncharacterized protein. (86 aa)
	DUI87_30226	CULLIN_2 domain-containing protein; Belongs to the cullin family. (1406 aa)
	DUI87_30022	Uncharacterized protein. (475 aa)
	DUI87_21219	RPN1_RPN2_N domain-containing protein. (876 aa)
	DUI87_14815	WD_REPEATS_REGION domain-containing protein. (503 aa)
	DUI87_16027	TPR_REGION domain-containing protein. (617 aa)
	DUI87_18494	SUI1 domain-containing protein. (1010 aa)
	DUI87_17300	TPR_REGION domain-containing protein. (565 aa)
	DUI87_11181	Uncharacterized protein. (122 aa)
	DUI87_12395	Uncharacterized protein. (473 aa)
	DUI87_10227	Proteasome subunit beta. (240 aa)
	DUI87_16950	Uncharacterized protein. (310 aa)
	DUI87_15499	Uncharacterized protein. (1585 aa)
	DUI87_15509	APC1_C domain-containing protein. (1822 aa)

Your Current Organism:

Hirundo rustica

NCBI taxonomy Id: 333673
Other names: H. rustica rustica, Hirundo rustica rustica

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DUI87_00237	DUI87_06560	A0A3M0LBG7	A0A3M0KTI8	VWFA domain-containing protein.	F-box domain-containing protein.	0.818
DUI87_00237	DUI87_09358	A0A3M0LBG7	A0A3M0L4U9	VWFA domain-containing protein.	Uncharacterized protein.	0.821
DUI87_00237	DUI87_09751	A0A3M0LBG7	A0A3M0KMP0	VWFA domain-containing protein.	Proteasome subunit alpha type.	0.999
DUI87_00237	DUI87_10227	A0A3M0LBG7	A0A3M0KHL1	VWFA domain-containing protein.	Proteasome subunit beta.	0.999
DUI87_00237	DUI87_10232	A0A3M0LBG7	A0A3M0KZY9	VWFA domain-containing protein.	Uncharacterized protein.	0.716
DUI87_00237	DUI87_12395	A0A3M0LBG7	A0A3M0KHF6	VWFA domain-containing protein.	Uncharacterized protein.	0.999
DUI87_00237	DUI87_13170	A0A3M0LBG7	A0A3M0KTA1	VWFA domain-containing protein.	AAA domain-containing protein; Belongs to the AAA ATPase family.	0.999
DUI87_00237	DUI87_14407	A0A3M0LBG7	A0A3M0K8B2	VWFA domain-containing protein.	MPN domain-containing protein.	0.999
DUI87_00237	DUI87_14815	A0A3M0LBG7	A0A3M0K602	VWFA domain-containing protein.	WD_REPEATS_REGION domain-containing protein.	0.727
DUI87_00237	DUI87_15490	A0A3M0LBG7	A0A3M0K4K2	VWFA domain-containing protein.	Ubiquitin-like domain-containing protein.	0.998
DUI87_00237	DUI87_15499	A0A3M0LBG7	A0A3M0KLE3	VWFA domain-containing protein.	Uncharacterized protein.	0.994
DUI87_00237	DUI87_15509	A0A3M0LBG7	A0A3M0KLF7	VWFA domain-containing protein.	APC1_C domain-containing protein.	0.824
DUI87_00237	DUI87_16027	A0A3M0LBG7	A0A3M0K687	VWFA domain-containing protein.	TPR_REGION domain-containing protein.	0.854
DUI87_00237	DUI87_17307	A0A3M0LBG7	A0A3M0K3G6	VWFA domain-containing protein.	ANAPC5 domain-containing protein.	0.806
DUI87_00237	DUI87_18494	A0A3M0LBG7	A0A3M0KDT5	VWFA domain-containing protein.	SUI1 domain-containing protein.	0.781
DUI87_00237	DUI87_18645	A0A3M0LBG7	A0A3M0JWM1	VWFA domain-containing protein.	Proteasome subunit alpha type.	0.999
DUI87_00237	DUI87_21217	A0A3M0LBG7	A0A3M0JMW7	VWFA domain-containing protein.	RPN2_C domain-containing protein.	0.994
DUI87_00237	DUI87_21219	A0A3M0LBG7	A0A3M0K4Q2	VWFA domain-containing protein.	RPN1_RPN2_N domain-containing protein.	0.994
DUI87_00237	DUI87_21815	A0A3M0LBG7	A0A3M0K2Q4	VWFA domain-containing protein.	Proteasome subunit beta.	0.997
DUI87_00237	DUI87_21828	A0A3M0LBG7	A0A3M0JRM7	VWFA domain-containing protein.	Proteasome subunit beta.	0.997