(46 nodes) SCF(Skp2)-mediated degradation of p27/p21 network (Hirundo rustica)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DUI87_31349	Protein kinase domain-containing protein. (767 aa)
	DUI87_33829	KxDL domain-containing protein. (176 aa)
	DUI87_06560	F-box domain-containing protein. (370 aa)
	DUI87_00237	VWFA domain-containing protein. (449 aa)
	DUI87_35402	Proteasome subunit beta. (233 aa)
	DUI87_13170	AAA domain-containing protein; Belongs to the AAA ATPase family. (416 aa)
	DUI87_07324	Uncharacterized protein; Belongs to the cyclin family. (364 aa)
	DUI87_09751	Proteasome subunit alpha type. (271 aa)
	DUI87_16950	Uncharacterized protein. (310 aa)
	DUI87_08573	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (406 aa)
	DUI87_10227	Proteasome subunit beta. (240 aa)
	DUI87_12395	Uncharacterized protein. (473 aa)
	DUI87_14407	MPN domain-containing protein. (295 aa)
	DUI87_14049	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (329 aa)
	DUI87_21219	RPN1_RPN2_N domain-containing protein. (876 aa)
	DUI87_15490	Ubiquitin-like domain-containing protein. (156 aa)
	DUI87_21815	Proteasome subunit beta. (239 aa)
	DUI87_16668	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (425 aa)
	DUI87_18591	CULLIN_2 domain-containing protein; Belongs to the cullin family. (671 aa)
	DUI87_22779	Uncharacterized protein. (161 aa)
	DUI87_24183	Proteasome subunit alpha type. (241 aa)
	DUI87_18645	Proteasome subunit alpha type. (182 aa)
	DUI87_24802	Proteasome subunit alpha type. (255 aa)
	DUI87_21828	Proteasome subunit beta. (202 aa)
	DUI87_22065	PCI domain-containing protein. (422 aa)
	DUI87_20092	Uncharacterized protein. (174 aa)
	DUI87_21217	RPN2_C domain-containing protein. (337 aa)
	DUI87_21941	Uncharacterized protein. (254 aa)
	DUI87_25042	AAA domain-containing protein; Belongs to the AAA ATPase family. (440 aa)
	DUI87_23189	Proteasome endopeptidase complex. (291 aa)
	DUI87_22923	AAA domain-containing protein; Belongs to the AAA ATPase family. (422 aa)
	DUI87_24519	PCI domain-containing protein. (389 aa)
	DUI87_25296	ANK_REP_REGION domain-containing protein. (226 aa)
	DUI87_24751	AAA domain-containing protein. (342 aa)
	DUI87_25422	PCI domain-containing protein. (393 aa)
	DUI87_25615	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (292 aa)
	DUI87_28290	PCI domain-containing protein. (386 aa)
	DUI87_26851	Uncharacterized protein; Belongs to the SKP1 family. (165 aa)
	DUI87_27870	Uncharacterized protein. (268 aa)
	DUI87_29993	Proteasome subunit beta. (277 aa)
	DUI87_29415	Proteasome subunit alpha type. (261 aa)
	DUI87_28531	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (79 aa)
	DUI87_28462	AAA domain-containing protein; Belongs to the AAA ATPase family. (377 aa)
	DUI87_30022	Uncharacterized protein. (475 aa)
	DUI87_32380	Proteasome subunit beta. (201 aa)
	DUI87_33245	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (316 aa)

Your Current Organism:

Hirundo rustica

NCBI taxonomy Id: 333673
Other names: H. rustica rustica, Hirundo rustica rustica

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DUI87_00237	DUI87_06560	A0A3M0LBG7	A0A3M0KTI8	VWFA domain-containing protein.	F-box domain-containing protein.	0.818
DUI87_00237	DUI87_08573	A0A3M0LBG7	A0A3M0KJR4	VWFA domain-containing protein.	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	0.775
DUI87_00237	DUI87_09751	A0A3M0LBG7	A0A3M0KMP0	VWFA domain-containing protein.	Proteasome subunit alpha type.	0.999
DUI87_00237	DUI87_10227	A0A3M0LBG7	A0A3M0KHL1	VWFA domain-containing protein.	Proteasome subunit beta.	0.999
DUI87_00237	DUI87_12395	A0A3M0LBG7	A0A3M0KHF6	VWFA domain-containing protein.	Uncharacterized protein.	0.999
DUI87_00237	DUI87_13170	A0A3M0LBG7	A0A3M0KTA1	VWFA domain-containing protein.	AAA domain-containing protein; Belongs to the AAA ATPase family.	0.999
DUI87_00237	DUI87_14407	A0A3M0LBG7	A0A3M0K8B2	VWFA domain-containing protein.	MPN domain-containing protein.	0.999
DUI87_00237	DUI87_15490	A0A3M0LBG7	A0A3M0K4K2	VWFA domain-containing protein.	Ubiquitin-like domain-containing protein.	0.998
DUI87_00237	DUI87_16668	A0A3M0LBG7	A0A3M0K1U6	VWFA domain-containing protein.	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	0.774
DUI87_00237	DUI87_18591	A0A3M0LBG7	A0A3M0JZ22	VWFA domain-containing protein.	CULLIN_2 domain-containing protein; Belongs to the cullin family.	0.891
DUI87_00237	DUI87_18645	A0A3M0LBG7	A0A3M0JWM1	VWFA domain-containing protein.	Proteasome subunit alpha type.	0.999
DUI87_00237	DUI87_21217	A0A3M0LBG7	A0A3M0JMW7	VWFA domain-containing protein.	RPN2_C domain-containing protein.	0.994
DUI87_00237	DUI87_21219	A0A3M0LBG7	A0A3M0K4Q2	VWFA domain-containing protein.	RPN1_RPN2_N domain-containing protein.	0.994
DUI87_00237	DUI87_21815	A0A3M0LBG7	A0A3M0K2Q4	VWFA domain-containing protein.	Proteasome subunit beta.	0.997
DUI87_00237	DUI87_21828	A0A3M0LBG7	A0A3M0JRM7	VWFA domain-containing protein.	Proteasome subunit beta.	0.997
DUI87_00237	DUI87_21941	A0A3M0LBG7	A0A3M0JK63	VWFA domain-containing protein.	Uncharacterized protein.	0.840
DUI87_00237	DUI87_22065	A0A3M0LBG7	A0A3M0JRA9	VWFA domain-containing protein.	PCI domain-containing protein.	0.999
DUI87_00237	DUI87_22923	A0A3M0LBG7	A0A3M0JH49	VWFA domain-containing protein.	AAA domain-containing protein; Belongs to the AAA ATPase family.	0.999
DUI87_00237	DUI87_23189	A0A3M0LBG7	A0A3M0JI39	VWFA domain-containing protein.	Proteasome endopeptidase complex.	0.999
DUI87_00237	DUI87_24183	A0A3M0LBG7	A0A3M0JWW4	VWFA domain-containing protein.	Proteasome subunit alpha type.	0.999