(34 nodes) Signaling by FGFR3 network (Hirundo rustica)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DUI87_15490	Ubiquitin-like domain-containing protein. (156 aa)
	DUI87_24142	Uncharacterized protein. (778 aa)
	DUI87_24077	IRS-type PTB domain-containing protein. (482 aa)
	DUI87_24141	Uncharacterized protein. (281 aa)
	DUI87_22848	Uncharacterized protein. (217 aa)
	DUI87_22507	Protein kinase domain-containing protein. (695 aa)
	DUI87_21125	Uncharacterized protein. (1301 aa)
	DUI87_19993	Uncharacterized protein; Belongs to the heparin-binding growth factors family. (256 aa)
	DUI87_20075	Uncharacterized protein. (1336 aa)
	DUI87_14886	Protein kinase domain-containing protein. (380 aa)
	DUI87_30905	Uncharacterized protein. (1229 aa)
	DUI87_16749	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (188 aa)
	DUI87_15267	Uncharacterized protein. (1164 aa)
	DUI87_17353	Uncharacterized protein. (551 aa)
	DUI87_23931	PH domain-containing protein. (668 aa)
	DUI87_20035	Uncharacterized protein. (250 aa)
	DUI87_21142	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (1053 aa)
	DUI87_11585	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (213 aa)
	DUI87_12759	IRS-type PTB domain-containing protein. (508 aa)
	DUI87_09519	Uncharacterized protein. (812 aa)
	DUI87_08565	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (243 aa)
	DUI87_12395	Uncharacterized protein. (473 aa)
	DUI87_30901	Uncharacterized protein. (277 aa)
	DUI87_31372	Uncharacterized protein. (203 aa)
	DUI87_30538	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (184 aa)
	DUI87_26610	Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
	DUI87_28532	Uncharacterized protein. (609 aa)
	DUI87_28092	Uncharacterized protein. (1051 aa)
	DUI87_25128	Uncharacterized protein. (375 aa)
	DUI87_09148	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (216 aa)
	DUI87_25612	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa)
	DUI87_25179	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
	DUI87_08663	Serine/threonine-protein phosphatase. (361 aa)
	DUI87_08711	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (258 aa)

Your Current Organism:

Hirundo rustica

NCBI taxonomy Id: 333673
Other names: H. rustica rustica, Hirundo rustica rustica

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DUI87_08565	DUI87_09519	A0A3M0KLH2	A0A3M0KN01	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Uncharacterized protein.	0.988
DUI87_08565	DUI87_11585	A0A3M0KLH2	A0A3M0KE32	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.467
DUI87_08565	DUI87_12395	A0A3M0KLH2	A0A3M0KHF6	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Uncharacterized protein.	0.634
DUI87_08565	DUI87_12759	A0A3M0KLH2	A0A3M0K9X8	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	IRS-type PTB domain-containing protein.	0.494
DUI87_08565	DUI87_15490	A0A3M0KLH2	A0A3M0K4K2	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Ubiquitin-like domain-containing protein.	0.737
DUI87_08565	DUI87_17353	A0A3M0KLH2	A0A3M0K3W6	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Uncharacterized protein.	0.427
DUI87_08565	DUI87_19993	A0A3M0KLH2	A0A3M0JP65	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Uncharacterized protein; Belongs to the heparin-binding growth factors family.	0.579
DUI87_08565	DUI87_21142	A0A3M0KLH2	A0A3M0JT86	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.448
DUI87_08565	DUI87_23931	A0A3M0KLH2	A0A3M0JXP1	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	PH domain-containing protein.	0.540
DUI87_08565	DUI87_24077	A0A3M0KLH2	A0A3M0JEF0	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	IRS-type PTB domain-containing protein.	0.487
DUI87_08565	DUI87_25612	A0A3M0KLH2	A0A3M0JBE6	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.599
DUI87_08565	DUI87_28532	A0A3M0KLH2	A0A3M0J881	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Uncharacterized protein.	0.437
DUI87_08565	DUI87_30538	A0A3M0KLH2	A0A3M0IX12	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.554
DUI87_08565	DUI87_31372	A0A3M0KLH2	A0A3M0IWH2	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Uncharacterized protein.	0.661
DUI87_08663	DUI87_12395	A0A3M0L2P8	A0A3M0KHF6	Serine/threonine-protein phosphatase.	Uncharacterized protein.	0.796
DUI87_08663	DUI87_14886	A0A3M0L2P8	A0A3M0K678	Serine/threonine-protein phosphatase.	Protein kinase domain-containing protein.	0.628
DUI87_08663	DUI87_15490	A0A3M0L2P8	A0A3M0K4K2	Serine/threonine-protein phosphatase.	Ubiquitin-like domain-containing protein.	0.778
DUI87_08663	DUI87_17353	A0A3M0L2P8	A0A3M0K3W6	Serine/threonine-protein phosphatase.	Uncharacterized protein.	0.625
DUI87_08663	DUI87_20035	A0A3M0L2P8	A0A3M0JUP1	Serine/threonine-protein phosphatase.	Uncharacterized protein.	0.677
DUI87_08663	DUI87_20075	A0A3M0L2P8	A0A3M0JPD9	Serine/threonine-protein phosphatase.	Uncharacterized protein.	0.893