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FMG_0317 FMG_0317 asd asd FMG_0319 FMG_0319 thrB thrB FMG_0342 FMG_0342 FMG_0388 FMG_0388 FMG_0406 FMG_0406 FMG_0456 FMG_0456 FMG_0474 FMG_0474 pfp pfp FMG_0669 FMG_0669 luxS luxS FMG_0750 FMG_0750 eno eno gpmI gpmI tpiA tpiA FMG_0796 FMG_0796 glyA glyA asnA asnA FMG_0992 FMG_0992 FMG_1001 FMG_1001 pfkA pfkA FMG_1138 FMG_1138 FMG_1149 FMG_1149 metK metK FMG_1222 FMG_1222 aroQ aroQ aroK aroK FMG_1239 FMG_1239 FMG_1240 FMG_1240 aroA aroA FMG_1242 FMG_1242 FMG_1243 FMG_1243 FMG_1252 FMG_1252 FMG_1264 FMG_1264 FMG_1283 FMG_1283 FMG_1311 FMG_1311 FMG_1465 FMG_1465 FMG_1503 FMG_1503 FMG_1504 FMG_1504 FMG_1537 FMG_1537 FMG_1572 FMG_1572
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
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FMG_0317Aspartate kinase; Belongs to the aspartokinase family. (436 aa)
asdAspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (324 aa)
FMG_0319Homoserine dehydrogenase. (393 aa)
thrBThreonine synthase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate. (764 aa)
FMG_0342Ribose 5-phosphate isomerase. (150 aa)
FMG_03885-methyltetrahydropteroyltriglutamate- homocysteine methyltransferase. (391 aa)
FMG_0406Putative histidinol-phosphatase; Belongs to the PHP hydrolase family. HisK subfamily. (263 aa)
FMG_0456Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. (329 aa)
FMG_04742,3-bisphosphoglycerate-independent phosphoglycerate mutase; Phosphoglyceromutase. (411 aa)
pfp6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. (375 aa)
FMG_0669Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (218 aa)
luxSAutoinducer-2 production protein; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family. (156 aa)
FMG_0750Aspartate transaminase. (391 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (428 aa)
gpmI2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (516 aa)
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (251 aa)
FMG_0796Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (655 aa)
glyASerine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (412 aa)
asnAAspartate-ammonia ligase. (336 aa)
FMG_0992Glutamine synthase type III; Belongs to the glutamine synthetase family. (684 aa)
FMG_1001Pyruvate kinase; Belongs to the pyruvate kinase family. (585 aa)
pfkA6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (319 aa)
FMG_1138Branched-chain amino acid aminotransferase. (353 aa)
FMG_1149Phosphoribosylpyrophosphate synthetase; Belongs to the ribose-phosphate pyrophosphokinase family. (368 aa)
metKS-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (392 aa)
FMG_1222Methylthioadenosine nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily. (225 aa)
aroQ3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (142 aa)
aroKShikimate 5-dehydrogenase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate dehydrogenase family. (403 aa)
FMG_1239Chorismate mutase. (83 aa)
FMG_1240Chorismate synthase. (363 aa)
aroA3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (401 aa)
FMG_12423-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (343 aa)
FMG_1243Carboxysome formation protein. (333 aa)
FMG_1252Low specificity L-threonine aldolase. (338 aa)
FMG_1264Threonine synthase. (480 aa)
FMG_1283Fructose-bisphosphate aldolase. (288 aa)
FMG_1311Conserved hypothetical protein. (371 aa)
FMG_1465Putative aspartate aminotransferase. (418 aa)
FMG_1503L-serine dehydratase alpha subunit; Belongs to the iron-sulfur dependent L-serine dehydratase family. (299 aa)
FMG_1504L-serine dehydratase beta subunit; Belongs to the iron-sulfur dependent L-serine dehydratase family. (220 aa)
FMG_1537Transaldolase. (236 aa)
FMG_1572Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1139 aa)
Your Current Organism:
Finegoldia magna ATCC 29328
NCBI taxonomy Id: 334413
Other names: F. magna ATCC 29328, Finegoldia magna str. ATCC 29328, Finegoldia magna strain ATCC 29328
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