(39 nodes) Valine, leucine and isoleucine degradation, and acetate-CoA ligase activity network (Fusarium verticillioides)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

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gene fusions

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Your Input:
	FVEG_17649	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. (434 aa)
	FVEG_13890	Acetyl-CoA acyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (327 aa)
	FVEG_14121	Peroxisomal multifunctional beta-oxidation protein. (740 aa)
	FVEG_00558	Hydroxymethylglutaryl-CoA lyase. (369 aa)
	FVEG_01973	3-methylcrotonyl-CoA carboxylase alpha subunit. (733 aa)
	FVEG_02181	Propionyl-CoA carboxylase beta chain. (568 aa)
	FVEG_00781	Acetyl-coenzyme A synthetase. (719 aa)
	FVEG_03315	Acetyl-CoA acyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (407 aa)
	FVEG_01781	Acetyl-CoA hydrolase. (526 aa)
	FVEG_01806	Acetyl-CoA acyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (417 aa)
	FVEG_05172	3-hydroxybutyryl-CoA dehydrogenase. (319 aa)
	FVEG_04808	Acyl-CoA dehydrogenase. (452 aa)
	FVEG_00948	Methylmalonate-semialdehyde dehydrogenase (Acylating). (570 aa)
	FVEG_05289	Enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (290 aa)
	FVEG_02850	Propionyl-CoA synthetase. (777 aa)
	FVEG_03313	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. (513 aa)
	FVEG_03792	Acetyl-CoA C-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (396 aa)
	FVEG_02182	Isovaleryl-CoA dehydrogenase. (427 aa)
	FVEG_04199	Peroxisomal hydratase-dehydrogenase-epimerase. (899 aa)
	FVEG_04720	Methylglutaconyl-CoA hydratase. (318 aa)
	FVEG_04725	Acetoacetate-CoA ligase. (697 aa)
	FVEG_07679	Methylmalonate-semialdehyde dehydrogenase (Acylating). (520 aa)
	FVEG_16149	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. (518 aa)
	FVEG_04053	Acetyl-CoA acyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (418 aa)
	FVEG_06071	Acetyl-CoA C-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (430 aa)
	FVEG_05017	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. (519 aa)
	FVEG_06269	Acyl-CoA dehydrogenase. (446 aa)
	FVEG_08487	Homocitrate synthase, mitochondrial; Belongs to the alpha-IPM synthase/homocitrate synthase family. (403 aa)
	FVEG_11982	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (698 aa)
	FVEG_12628	3-hydroxyacyl-CoA dehydrogenase. (322 aa)
	FVEG_09899	Acetyl-coenzyme A synthetase. (663 aa)
	FVEG_07774	Enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (270 aa)
	FVEG_10286	Acetoacetate-CoA ligase. (699 aa)
	FVEG_10433	Acetyl-CoA acyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (416 aa)
	FVEG_08517	Enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (258 aa)
	FVEG_14162	Uncharacterized protein. (235 aa)
	FVEG_11476	Glutaryl-CoA dehydrogenase. (426 aa)
	FVEG_11645	Acyl-CoA dehydrogenase. (434 aa)
	FVEG_11842	Enoyl-CoA hydratase. (262 aa)

Your Current Organism:

Fusarium verticillioides

NCBI taxonomy Id: 334819
Other names: F. verticillioides 7600, Fusarium verticillioides 7600, Gibberella moniliformis 7600

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
FVEG_00558	FVEG_01806	W7LDF0	W7LT43	Hydroxymethylglutaryl-CoA lyase.	Acetyl-CoA acyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	0.926
FVEG_00558	FVEG_01973	W7LDF0	W7LKA2	Hydroxymethylglutaryl-CoA lyase.	3-methylcrotonyl-CoA carboxylase alpha subunit.	0.609
FVEG_00558	FVEG_02181	W7LDF0	W7LLA2	Hydroxymethylglutaryl-CoA lyase.	Propionyl-CoA carboxylase beta chain.	0.817
FVEG_00558	FVEG_03313	W7LDF0	W7M0W9	Hydroxymethylglutaryl-CoA lyase.	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.	0.934
FVEG_00558	FVEG_03315	W7LDF0	W7LRI0	Hydroxymethylglutaryl-CoA lyase.	Acetyl-CoA acyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	0.926
FVEG_00558	FVEG_03792	W7LDF0	W7M2F9	Hydroxymethylglutaryl-CoA lyase.	Acetyl-CoA C-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	0.933
FVEG_00558	FVEG_04053	W7LDF0	W7MBC1	Hydroxymethylglutaryl-CoA lyase.	Acetyl-CoA acyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	0.926
FVEG_00558	FVEG_04720	W7LDF0	W7M6A0	Hydroxymethylglutaryl-CoA lyase.	Methylglutaconyl-CoA hydratase.	0.980
FVEG_00558	FVEG_04725	W7LDF0	W7M6B3	Hydroxymethylglutaryl-CoA lyase.	Acetoacetate-CoA ligase.	0.933
FVEG_00558	FVEG_05017	W7LDF0	W7MFR7	Hydroxymethylglutaryl-CoA lyase.	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.	0.934
FVEG_00558	FVEG_05172	W7LDF0	W7LXC9	Hydroxymethylglutaryl-CoA lyase.	3-hydroxybutyryl-CoA dehydrogenase.	0.425
FVEG_00558	FVEG_05289	W7LDF0	W7LXW0	Hydroxymethylglutaryl-CoA lyase.	Enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family.	0.530
FVEG_00558	FVEG_06071	W7LDF0	W7MC27	Hydroxymethylglutaryl-CoA lyase.	Acetyl-CoA C-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	0.933
FVEG_00558	FVEG_07774	W7LDF0	W7MT49	Hydroxymethylglutaryl-CoA lyase.	Enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family.	0.443
FVEG_00558	FVEG_08517	W7LDF0	W7MWK7	Hydroxymethylglutaryl-CoA lyase.	Enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family.	0.443
FVEG_00558	FVEG_10286	W7LDF0	W7MU56	Hydroxymethylglutaryl-CoA lyase.	Acetoacetate-CoA ligase.	0.933
FVEG_00558	FVEG_10433	W7LDF0	W7MUY8	Hydroxymethylglutaryl-CoA lyase.	Acetyl-CoA acyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	0.926
FVEG_00558	FVEG_11842	W7LDF0	W7N011	Hydroxymethylglutaryl-CoA lyase.	Enoyl-CoA hydratase.	0.530
FVEG_00558	FVEG_11982	W7LDF0	W7MQ54	Hydroxymethylglutaryl-CoA lyase.	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family.	0.430
FVEG_00558	FVEG_13890	W7LDF0	A0A139YBG0	Hydroxymethylglutaryl-CoA lyase.	Acetyl-CoA acyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	0.926