(21 nodes) Glutathione metabolism network (Fusarium verticillioides)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	FVEG_00186	Glutathione S-transferase; Belongs to the GST superfamily. (276 aa)
	FVEG_01424	Uncharacterized protein; Belongs to the GST superfamily. (533 aa)
	FVEG_02608	Cytosolic nonspecific dipeptidase. (536 aa)
	FVEG_02789	Glutamate-cysteine ligase. (716 aa)
	FVEG_00903	Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family. (231 aa)
	FVEG_03586	5-oxoprolinase (ATP-hydrolysing). (1306 aa)
	FVEG_01597	Peroxiredoxin (Alkyl hydroperoxide reductase subunit C). (259 aa)
	FVEG_03657	Gamma-glutamyltransferase. (580 aa)
	FVEG_04856	Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. (506 aa)
	FVEG_02933	5-oxoprolinase (ATP-hydrolysing). (1359 aa)
	FVEG_02759	Aldo_ket_red domain-containing protein. (312 aa)
	FVEG_04419	Glutathione S-transferase; Belongs to the GST superfamily. (222 aa)
	FVEG_05312	Glutathione synthetase. (516 aa)
	FVEG_07731	Uncharacterized protein; Belongs to the GST superfamily. (185 aa)
	FVEG_10652	Uncharacterized protein; Belongs to the GST superfamily. (216 aa)
	FVEG_12761	Peroxidase. (227 aa)
	FVEG_13005	Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. (464 aa)
	FVEG_10403	Glutathione S-transferase; Belongs to the GST superfamily. (302 aa)
	FVEG_10344	Glutathione S-transferase. (281 aa)
	FVEG_11101	Gamma-glutamyltranspeptidase. (604 aa)
	FVEG_17046	Gamma-glutamyltransferase. (565 aa)

Your Current Organism:

Fusarium verticillioides

NCBI taxonomy Id: 334819
Other names: F. verticillioides 7600, Fusarium verticillioides 7600, Gibberella moniliformis 7600

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
FVEG_00186	FVEG_00903	W7LBP8	W7LNX5	Glutathione S-transferase; Belongs to the GST superfamily.	Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family.	0.921
FVEG_00186	FVEG_01597	W7LBP8	W7LS54	Glutathione S-transferase; Belongs to the GST superfamily.	Peroxiredoxin (Alkyl hydroperoxide reductase subunit C).	0.686
FVEG_00186	FVEG_03657	W7LBP8	W7LSN4	Glutathione S-transferase; Belongs to the GST superfamily.	Gamma-glutamyltransferase.	0.755
FVEG_00186	FVEG_04419	W7LBP8	W7MCX7	Glutathione S-transferase; Belongs to the GST superfamily.	Glutathione S-transferase; Belongs to the GST superfamily.	0.410
FVEG_00186	FVEG_04856	W7LBP8	W7LXK6	Glutathione S-transferase; Belongs to the GST superfamily.	Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.	0.728
FVEG_00186	FVEG_05312	W7LBP8	W7MH70	Glutathione S-transferase; Belongs to the GST superfamily.	Glutathione synthetase.	0.932
FVEG_00186	FVEG_07731	W7LBP8	W7MJ72	Glutathione S-transferase; Belongs to the GST superfamily.	Uncharacterized protein; Belongs to the GST superfamily.	0.410
FVEG_00186	FVEG_10344	W7LBP8	W7N3G7	Glutathione S-transferase; Belongs to the GST superfamily.	Glutathione S-transferase.	0.418
FVEG_00186	FVEG_10652	W7LBP8	W7MK51	Glutathione S-transferase; Belongs to the GST superfamily.	Uncharacterized protein; Belongs to the GST superfamily.	0.410
FVEG_00186	FVEG_11101	W7LBP8	W7N6Q7	Glutathione S-transferase; Belongs to the GST superfamily.	Gamma-glutamyltranspeptidase.	0.712
FVEG_00186	FVEG_12761	W7LBP8	W7MTT2	Glutathione S-transferase; Belongs to the GST superfamily.	Peroxidase.	0.686
FVEG_00186	FVEG_13005	W7LBP8	W7MUS9	Glutathione S-transferase; Belongs to the GST superfamily.	Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.	0.728
FVEG_00186	FVEG_17046	W7LBP8	W7N974	Glutathione S-transferase; Belongs to the GST superfamily.	Gamma-glutamyltransferase.	0.755
FVEG_00903	FVEG_00186	W7LNX5	W7LBP8	Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family.	Glutathione S-transferase; Belongs to the GST superfamily.	0.921
FVEG_00903	FVEG_01424	W7LNX5	W7LF42	Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family.	Uncharacterized protein; Belongs to the GST superfamily.	0.921
FVEG_00903	FVEG_01597	W7LNX5	W7LS54	Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family.	Peroxiredoxin (Alkyl hydroperoxide reductase subunit C).	0.901
FVEG_00903	FVEG_02608	W7LNX5	W7LKV3	Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family.	Cytosolic nonspecific dipeptidase.	0.900
FVEG_00903	FVEG_02933	W7LNX5	W7LZ72	Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family.	5-oxoprolinase (ATP-hydrolysing).	0.911
FVEG_00903	FVEG_03586	W7LNX5	W7LQM7	Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family.	5-oxoprolinase (ATP-hydrolysing).	0.911
FVEG_00903	FVEG_03657	W7LNX5	W7LSN4	Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family.	Gamma-glutamyltransferase.	0.907