(129 nodes) Positive regulation of transcription by RNA polymerase II network (Fusarium verticillioides)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	FVEG_02637	Plus3 domain-containing protein. (522 aa)
	FVEG_12118	Zn(2)-C6 fungal-type domain-containing protein. (713 aa)
	FVEG_11161	SAGA-associated factor 29. (454 aa)
	FVEG_13486	Uncharacterized protein. (1250 aa)
	FVEG_13087	BZIP domain-containing protein. (505 aa)
	FVEG_13000	Abhydrolase_3 domain-containing protein. (327 aa)
	FVEG_10296	Zn(2)-C6 fungal-type domain-containing protein. (1018 aa)
	FVEG_12480	BHLH domain-containing protein. (223 aa)
	FVEG_12457	Beta-lactamase. (412 aa)
	FVEG_16685	Zn(2)-C6 fungal-type domain-containing protein. (768 aa)
	FVEG_09700	26S protease regulatory subunit 8; Belongs to the AAA ATPase family. (389 aa)
	FVEG_09523	ANK_REP_REGION domain-containing protein. (1404 aa)
	FVEG_09485	Uncharacterized protein. (119 aa)
	FVEG_11860	Abhydrolase_3 domain-containing protein. (348 aa)
	FVEG_11861	Zn(2)-C6 fungal-type domain-containing protein. (602 aa)
	FVEG_09273	LisH domain-containing protein. (721 aa)
	FVEG_11432	26S protease regulatory subunit 6B; Belongs to the AAA ATPase family. (421 aa)
	FVEG_08684	BHLH domain-containing protein. (280 aa)
	FVEG_11146	Uncharacterized protein. (450 aa)
	FVEG_10756	Uncharacterized protein. (2997 aa)
	FVEG_13172	Beta-lactamase. (410 aa)
	FVEG_08110	Transcriptional regulatory protein Pro-1. (686 aa)
	FVEG_10454	Transcription initiation factor TFIIF subunit alpha. (665 aa)
	FVEG_10532	Zn(2)-C6 fungal-type domain-containing protein. (729 aa)
	FVEG_07926	Uncharacterized protein. (495 aa)
	FVEG_10132	Abhydrolase_3 domain-containing protein. (350 aa)
	FVEG_17363	Zn(2)-C6 fungal-type domain-containing protein. (681 aa)
	FVEG_09904	Beta-lactamase. (399 aa)
	FVEG_12183	Uncharacterized protein. (460 aa)
	FVEG_09250	Uncharacterized protein. (252 aa)
	FVEG_09223	CBFD_NFYB_HMF domain-containing protein. (271 aa)
	FVEG_11754	Abhydrolase_3 domain-containing protein. (338 aa)
	FVEG_08900	26S protease regulatory subunit 6A; Belongs to the AAA ATPase family. (462 aa)
	FVEG_11371	Uncharacterized protein. (401 aa)
	FVEG_11339	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (736 aa)
	FVEG_11322	Uncharacterized protein. (752 aa)
	FVEG_08310	Uncharacterized protein. (667 aa)
	FVEG_08252	Fork-head domain-containing protein. (772 aa)
	FVEG_08005	NDT80 domain-containing protein. (662 aa)
	FVEG_10521	Uncharacterized protein. (2574 aa)
	FVEG_10410	Uncharacterized protein. (805 aa)
	FVEG_10380	Zn(2)-C6 fungal-type domain-containing protein. (784 aa)
	FVEG_07771	Uncharacterized protein. (840 aa)
	FVEG_07521	Zn(2)-C6 fungal-type domain-containing protein. (603 aa)
	FVEG_16075	Uncharacterized protein. (1497 aa)
	FVEG_05393	pH-response transcription factor pacC/RIM101. (638 aa)
	FVEG_05271	Uncharacterized protein. (1421 aa)
	FVEG_09639	Uncharacterized protein. (1499 aa)
	FVEG_09562	Uncharacterized protein. (637 aa)
	FVEG_09237	Uncharacterized protein. (361 aa)
	FVEG_09177	Glucose repression regulatory protein TUP1. (625 aa)
	FVEG_04505	F-box domain-containing protein. (506 aa)
	FVEG_06107	Zn(2)-C6 fungal-type domain-containing protein. (956 aa)
	FVEG_08660	Abhydrolase_3 domain-containing protein. (321 aa)
	FVEG_06055	GATA-type domain-containing protein. (517 aa)
	FVEG_15777	Uncharacterized protein. (328 aa)
	FVEG_05856	Abhydrolase_3 domain-containing protein. (354 aa)
	FVEG_05842	Abhydrolase_3 domain-containing protein. (327 aa)
	FVEG_08087	Nuclear transcription Y subunit beta. (198 aa)
	FVEG_05532	Zn(2)-C6 fungal-type domain-containing protein. (555 aa)
	FVEG_08327	Uncharacterized protein. (526 aa)
	FVEG_07834	CMGC/CDK/CDK7 protein kinase; Belongs to the protein kinase superfamily. (413 aa)
	FVEG_05364	ATPase_AAA_core domain-containing protein. (725 aa)
	FVEG_05195	CMGC/CDK/CRK7 protein kinase. (1019 aa)
	FVEG_07339	Myb-like DNA-binding protein FlbD. (281 aa)
	FVEG_07308	Uncharacterized protein. (307 aa)
	FVEG_07303	PAS domain-containing protein. (659 aa)
	FVEG_03115	Uncharacterized protein. (676 aa)
	FVEG_04861	BRCT domain-containing protein. (1171 aa)
	FVEG_07027	CBFD_NFYB_HMF domain-containing protein. (328 aa)
	FVEG_07145	Uncharacterized protein. (617 aa)
	FVEG_02619	Transcription elongation factor Spt6; Plays a role in maintenance of chromatin structure during RNA polymerase II transcription elongation thereby repressing transcription initiation from cryptic promoters. Mediates the reassembly of nucleosomes onto the promoters of at least a selected set of genes during repression; the nucleosome reassembly is essential for transcriptional repression; Belongs to the SPT6 family. (1406 aa)
	FVEG_02603	RING-type domain-containing protein. (644 aa)
	FVEG_06850	Histone deacetylase HOS3. (1167 aa)
	FVEG_04118	Uncharacterized protein. (557 aa)
	FVEG_03846	Abhydrolase_3 domain-containing protein. (477 aa)
	FVEG_03759	MADS-box transcription factor, other eukaryote. (652 aa)
	FVEG_06315	NDT80 domain-containing protein. (585 aa)
	FVEG_06190	CDC73_C domain-containing protein. (409 aa)
	FVEG_05392	Uncharacterized protein. (351 aa)
	FVEG_05365	AAA domain-containing protein. (868 aa)
	FVEG_01476	Uncharacterized protein. (725 aa)
	FVEG_02904	Multiprotein-bridging factor 1. (152 aa)
	FVEG_02943	E3 ubiquitin-protein ligase. (810 aa)
	FVEG_05036	Response regulatory domain-containing protein. (586 aa)
	FVEG_04932	BHLH domain-containing protein. (452 aa)
	FVEG_04638	Uncharacterized protein. (142 aa)
	FVEG_05033	CP2 domain-containing protein. (789 aa)
	FVEG_04962	TPR_REGION domain-containing protein. (864 aa)
	FVEG_02255	Abhydrolase_3 domain-containing protein. (347 aa)
	FVEG_02244	Abhydrolase_3 domain-containing protein. (336 aa)
	FVEG_04220	Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family. (115 aa)
	FVEG_02030	Med12 domain-containing protein. (1525 aa)
	FVEG_04038	Uncharacterized protein. (255 aa)
	FVEG_01965	MADS-box transcription factor, other eukaryote. (222 aa)
	FVEG_01948	Uncharacterized protein. (582 aa)
	FVEG_01730	Uncharacterized protein. (235 aa)
	FVEG_01719	Uncharacterized protein. (368 aa)
	FVEG_03891	Negative cofactor 2 complex subunit beta. (138 aa)
	FVEG_01504	HMG box domain-containing protein. (495 aa)
	FVEG_01466	Prefoldin, alpha subunit. (154 aa)
	FVEG_03833	Uncharacterized protein. (361 aa)
	FVEG_01436	BHLH domain-containing protein. (521 aa)
	FVEG_01325	26S protease subunit rpt4; Belongs to the AAA ATPase family. (391 aa)
	FVEG_03630	Abhydrolase_3 domain-containing protein. (324 aa)
	FVEG_03578	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (114 aa)
	FVEG_01203	Zn(2)-C6 fungal-type domain-containing protein. (910 aa)
	FVEG_02946	Adenosinetriphosphatase. (1116 aa)
	FVEG_00974	Uncharacterized protein. (406 aa)
	FVEG_02913	PC4 domain-containing protein. (148 aa)
	FVEG_02872	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (674 aa)
	FVEG_02152	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (1110 aa)
	FVEG_02065	Acid phosphatase. (529 aa)
	FVEG_02520	Histone-lysine N-methyltransferase ASH1L. (786 aa)
	FVEG_00037	Triacylglycerol lipase. (335 aa)
	FVEG_00075	TcA_TcB_BD domain-containing protein. (232 aa)
	FVEG_01786	GCR1_C domain-containing protein. (464 aa)
	FVEG_14842	Uncharacterized protein. (842 aa)
	FVEG_01300	BHLH domain-containing protein. (492 aa)
	FVEG_01284	YTH domain-containing protein. (637 aa)
	FVEG_01402	PLK protein kinase. (1005 aa)
	FVEG_01147	Uncharacterized protein. (632 aa)
	FVEG_01003	BHLH domain-containing protein. (657 aa)
	FVEG_00879	Uncharacterized protein. (899 aa)
	FVEG_00464	Uncharacterized protein. (518 aa)
	FVEG_00433	BHLH domain-containing protein. (116 aa)
	FVEG_00066	Zn(2)-C6 fungal-type domain-containing protein. (461 aa)
	FVEG_17697	Zn(2)-C6 fungal-type domain-containing protein. (547 aa)
	FVEG_17644	Zn(2)-C6 fungal-type domain-containing protein. (537 aa)

Your Current Organism:

Fusarium verticillioides

NCBI taxonomy Id: 334819
Other names: F. verticillioides 7600, Fusarium verticillioides 7600, Gibberella moniliformis 7600

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
FVEG_00075	FVEG_02619	W7LK27	W7M599	TcA_TcB_BD domain-containing protein.	Transcription elongation factor Spt6; Plays a role in maintenance of chromatin structure during RNA polymerase II transcription elongation thereby repressing transcription initiation from cryptic promoters. Mediates the reassembly of nucleosomes onto the promoters of at least a selected set of genes during repression; the nucleosome reassembly is essential for transcriptional repression; Belongs to the SPT6 family.	0.546
FVEG_00433	FVEG_04932	W7L9W2	W7LY09	BHLH domain-containing protein.	BHLH domain-containing protein.	0.897
FVEG_00433	FVEG_12480	W7L9W2	W7N266	BHLH domain-containing protein.	BHLH domain-containing protein.	0.894
FVEG_00464	FVEG_09639	W7LA00	W7MFM0	Uncharacterized protein.	Uncharacterized protein.	0.557
FVEG_00879	FVEG_01003	W7LC81	W7LD32	Uncharacterized protein.	BHLH domain-containing protein.	0.407
FVEG_00879	FVEG_09639	W7LC81	W7MFM0	Uncharacterized protein.	Uncharacterized protein.	0.557
FVEG_00974	FVEG_01719	W7LPA1	W7LSS2	Uncharacterized protein.	Uncharacterized protein.	0.429
FVEG_00974	FVEG_02619	W7LPA1	W7M599	Uncharacterized protein.	Transcription elongation factor Spt6; Plays a role in maintenance of chromatin structure during RNA polymerase II transcription elongation thereby repressing transcription initiation from cryptic promoters. Mediates the reassembly of nucleosomes onto the promoters of at least a selected set of genes during repression; the nucleosome reassembly is essential for transcriptional repression; Belongs to the SPT6 family.	0.944
FVEG_00974	FVEG_02637	W7LPA1	W7LX68	Uncharacterized protein.	Plus3 domain-containing protein.	0.997
FVEG_00974	FVEG_02872	W7LPA1	W7LM77	Uncharacterized protein.	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.457
FVEG_00974	FVEG_04962	W7LPA1	W7LWB9	Uncharacterized protein.	TPR_REGION domain-containing protein.	0.429
FVEG_00974	FVEG_05195	W7LPA1	W7M8S1	Uncharacterized protein.	CMGC/CDK/CRK7 protein kinase.	0.457
FVEG_00974	FVEG_06190	W7LPA1	W7M1D0	Uncharacterized protein.	CDC73_C domain-containing protein.	0.999
FVEG_00974	FVEG_06850	W7LPA1	W7M412	Uncharacterized protein.	Histone deacetylase HOS3.	0.443
FVEG_00974	FVEG_11339	W7LPA1	W7MME8	Uncharacterized protein.	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	0.443
FVEG_00974	FVEG_12183	W7LPA1	W7MQU2	Uncharacterized protein.	Uncharacterized protein.	0.429
FVEG_01003	FVEG_00879	W7LD32	W7LC81	BHLH domain-containing protein.	Uncharacterized protein.	0.407
FVEG_01325	FVEG_02904	W7LR33	W7LZ32	26S protease subunit rpt4; Belongs to the AAA ATPase family.	Multiprotein-bridging factor 1.	0.436
FVEG_01325	FVEG_02946	W7LR33	W7LQ22	26S protease subunit rpt4; Belongs to the AAA ATPase family.	Adenosinetriphosphatase.	0.418
FVEG_01325	FVEG_03578	W7LR33	W7LQL9	26S protease subunit rpt4; Belongs to the AAA ATPase family.	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.	0.633