(31 nodes) Butanoate metabolism network (Fusarium verticillioides)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	FVEG_17649	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. (434 aa)
	FVEG_14028	Uncharacterized protein. (449 aa)
	FVEG_00558	Hydroxymethylglutaryl-CoA lyase. (369 aa)
	FVEG_01669	Succinate-semialdehyde dehydrogenase. (499 aa)
	FVEG_00170	Succinate-semialdehyde dehydrogenase (NADP+); Belongs to the aldehyde dehydrogenase family. (498 aa)
	FVEG_00612	Succinate-semialdehyde dehydrogenase. (527 aa)
	FVEG_01576	Succinate-semialdehyde dehydrogenase. (499 aa)
	FVEG_05172	3-hydroxybutyryl-CoA dehydrogenase. (319 aa)
	FVEG_05239	4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (459 aa)
	FVEG_05289	Enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (290 aa)
	FVEG_03313	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. (513 aa)
	FVEG_03792	Acetyl-CoA C-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (396 aa)
	FVEG_06111	DAO domain-containing protein. (413 aa)
	FVEG_03844	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (456 aa)
	FVEG_04725	Acetoacetate-CoA ligase. (697 aa)
	FVEG_04952	Acetolactate synthase I/III small subunit. (312 aa)
	FVEG_05238	Succinate-semialdehyde dehydrogenase. (490 aa)
	FVEG_16149	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. (518 aa)
	FVEG_08157	Glutamate decarboxylase. (506 aa)
	FVEG_06071	Acetyl-CoA C-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (430 aa)
	FVEG_04334	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (493 aa)
	FVEG_05017	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. (519 aa)
	FVEG_10267	Acetolactate synthase. (684 aa)
	FVEG_09655	Glutamate decarboxylase; Belongs to the group II decarboxylase family. (580 aa)
	FVEG_10384	Succinate-semialdehyde dehydrogenase (NADP+); Belongs to the aldehyde dehydrogenase family. (404 aa)
	FVEG_06940	4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (502 aa)
	FVEG_12628	3-hydroxyacyl-CoA dehydrogenase. (322 aa)
	FVEG_07774	Enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (270 aa)
	FVEG_10286	Acetoacetate-CoA ligase. (699 aa)
	FVEG_08517	Enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (258 aa)
	FVEG_11842	Enoyl-CoA hydratase. (262 aa)

Your Current Organism:

Fusarium verticillioides

NCBI taxonomy Id: 334819
Other names: F. verticillioides 7600, Fusarium verticillioides 7600, Gibberella moniliformis 7600

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
FVEG_00170	FVEG_04725	W7LKD2	W7M6B3	Succinate-semialdehyde dehydrogenase (NADP+); Belongs to the aldehyde dehydrogenase family.	Acetoacetate-CoA ligase.	0.458
FVEG_00170	FVEG_05239	W7LKD2	W7LXN2	Succinate-semialdehyde dehydrogenase (NADP+); Belongs to the aldehyde dehydrogenase family.	4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	0.948
FVEG_00170	FVEG_06940	W7LKD2	W7MPB8	Succinate-semialdehyde dehydrogenase (NADP+); Belongs to the aldehyde dehydrogenase family.	4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	0.948
FVEG_00170	FVEG_09655	W7LKD2	W7MHW0	Succinate-semialdehyde dehydrogenase (NADP+); Belongs to the aldehyde dehydrogenase family.	Glutamate decarboxylase; Belongs to the group II decarboxylase family.	0.462
FVEG_00170	FVEG_10286	W7LKD2	W7MU56	Succinate-semialdehyde dehydrogenase (NADP+); Belongs to the aldehyde dehydrogenase family.	Acetoacetate-CoA ligase.	0.458
FVEG_00558	FVEG_03313	W7LDF0	W7M0W9	Hydroxymethylglutaryl-CoA lyase.	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.	0.934
FVEG_00558	FVEG_03792	W7LDF0	W7M2F9	Hydroxymethylglutaryl-CoA lyase.	Acetyl-CoA C-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	0.933
FVEG_00558	FVEG_03844	W7LDF0	W7M2P1	Hydroxymethylglutaryl-CoA lyase.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.974
FVEG_00558	FVEG_04725	W7LDF0	W7M6B3	Hydroxymethylglutaryl-CoA lyase.	Acetoacetate-CoA ligase.	0.933
FVEG_00558	FVEG_04952	W7LDF0	W7M7U8	Hydroxymethylglutaryl-CoA lyase.	Acetolactate synthase I/III small subunit.	0.534
FVEG_00558	FVEG_05017	W7LDF0	W7MFR7	Hydroxymethylglutaryl-CoA lyase.	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.	0.934
FVEG_00558	FVEG_05172	W7LDF0	W7LXC9	Hydroxymethylglutaryl-CoA lyase.	3-hydroxybutyryl-CoA dehydrogenase.	0.425
FVEG_00558	FVEG_05289	W7LDF0	W7LXW0	Hydroxymethylglutaryl-CoA lyase.	Enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family.	0.530
FVEG_00558	FVEG_06071	W7LDF0	W7MC27	Hydroxymethylglutaryl-CoA lyase.	Acetyl-CoA C-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	0.933
FVEG_00558	FVEG_07774	W7LDF0	W7MT49	Hydroxymethylglutaryl-CoA lyase.	Enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family.	0.443
FVEG_00558	FVEG_08517	W7LDF0	W7MWK7	Hydroxymethylglutaryl-CoA lyase.	Enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family.	0.443
FVEG_00558	FVEG_10286	W7LDF0	W7MU56	Hydroxymethylglutaryl-CoA lyase.	Acetoacetate-CoA ligase.	0.933
FVEG_00558	FVEG_11842	W7LDF0	W7N011	Hydroxymethylglutaryl-CoA lyase.	Enoyl-CoA hydratase.	0.530
FVEG_00558	FVEG_16149	W7LDF0	W7M961	Hydroxymethylglutaryl-CoA lyase.	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.	0.934
FVEG_00558	FVEG_17649	W7LDF0	A0A139YBC9	Hydroxymethylglutaryl-CoA lyase.	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.	0.934