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| | glmU | UDP-N-acetylglucosamine pyrophosphorylase / glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the t [...] (449 aa) |
| | prs | Ribose-phosphate diphosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (317 aa) |
| | Swol_0088 | Hypothetical protein; KEGG: mta:Moth_0091 septum formation initiator. (84 aa) |
| | Swol_0126 | KEGG: mta:Moth_0517 N-acetylmuramoyl-L-alanine amidase. (907 aa) |
| | minC | Septum site-determining protein MinC; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family. (197 aa) |
| | minE1 | Cell division topological specificity factor MinE; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell. (81 aa) |
| | Swol_0346 | KEGG: mta:Moth_0542 septum site-determining protein MinD. (273 aa) |
| | Swol_0489 | Peptidoglycan glycosyltransferase; KEGG: tte:TTE1258 cell division protein FtsI/penicillin-binding protein 2. (568 aa) |
| | Swol_0756 | KEGG: sth:STH3250 hypothetical protein. (204 aa) |
| | Swol_0763 | KEGG: mta:Moth_0937 vacuolar-type H+-ATPase subunit H. (149 aa) |
| | mraZ | KEGG: mta:Moth_0834 protein of unknown function UPF0040; Belongs to the MraZ family. (143 aa) |
| | Swol_0819 | Hypothetical protein. (166 aa) |
| | Swol_0820 | Peptidoglycan glycosyltransferase; KEGG: mta:Moth_0837 stage V sporulation protein D. (705 aa) |
| | murE | UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. (489 aa) |
| | murF | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. (466 aa) |
| | mraY | Phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. (324 aa) |
| | murD | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. (453 aa) |
| | Swol_0825 | KEGG: mta:Moth_0842 cell cycle protein; Belongs to the SEDS family. (364 aa) |
| | murG | Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. (367 aa) |
| | murC | UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. (465 aa) |
| | murA | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (416 aa) |
| | Swol_0829 | Cell division protein FtsQ; Essential cell division protein. (249 aa) |
| | Swol_0830 | KEGG: tte:TTE1642 hypothetical protein. (239 aa) |
| | Swol_0831 | KEGG: mta:Moth_0848 protein of unknown function DUF1290. (95 aa) |
| | ftsA | Cell division protein FtsA; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family. (410 aa) |
| | ftsZ | Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. (355 aa) |
| | Swol_0921 | KEGG: gka:GK3406 penicillin-binding protein. (649 aa) |
| | Swol_0950 | Hypothetical protein. (96 aa) |
| | Swol_0953 | Protein of unknown function UPF0001; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. (225 aa) |
| | sepF | Conserved hypothetical protein; Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA. (142 aa) |
| | Swol_0956 | KEGG: mta:Moth_0861 protein of unknown function YGGT. (89 aa) |
| | Swol_0957 | Collagenase and related proteases-like protein; KEGG: mac:MA0538 peptidase family protein U32. (643 aa) |
| | Swol_0958 | KEGG: tte:TTE1596 Cell division initiation protein. (164 aa) |
| | Swol_0959 | KEGG: bba:Bd0463 hypothetical protein; Belongs to the UPF0235 family. (102 aa) |
| | murB | UDP-N-acetylmuramate dehydrogenase; Cell wall formation. (299 aa) |
| | Swol_1100 | Soluble lytic murein transglycosylase and related regulatory protein; KEGG: oih:OB2138 lytic transglycosylase. (174 aa) |
| | Swol_1109 | Peptidoglycan glycosyltransferase; KEGG: mta:Moth_1710 penicillin-binding protein 1A. (795 aa) |
| | ddl | D-alanine--D-alanine ligase; Cell wall formation. (309 aa) |
| | Swol_1247 | KEGG: chy:CHY_0674 putative cell-wall associated endopeptidase. (257 aa) |
| | Swol_1249 | Thermostable dipeptidase. Metallo peptidase. MEROPS family M19; KEGG: tte:TTE2129 Zn-dependent dipeptidase, microsomal dipeptidase homolog. (311 aa) |
| | Swol_1263 | Conserved hypothetical protein; KEGG: mta:Moth_1073 transcriptional regulator, XRE family. (245 aa) |
| | Swol_1350 | KEGG: tte:TTE2785 UDP-N-acetylmuramyl tripeptide synthase; Belongs to the MurCDEF family. (887 aa) |
| | Swol_1518 | KEGG: bha:BH1295 hypothetical protein. (241 aa) |
| | rodA | Rod shape-determining protein RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily. (378 aa) |
| | minE2 | Cell division topological specificity factor MinE; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell. (90 aa) |
| | Swol_1636 | KEGG: chy:CHY_0348 septum site-determining protein MinD. (266 aa) |
| | minC-2 | Septum site-determining protein MinC; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family. (205 aa) |
| | Swol_1638 | KEGG: mta:Moth_0540 peptidoglycan glycosyltransferase. (703 aa) |
| | Swol_1639 | KEGG: mta:Moth_0539 hypothetical protein. (167 aa) |
| | Swol_1640 | Rod shape-determining protein MreC; Involved in formation and maintenance of cell shape. (288 aa) |
| | Swol_1641 | KEGG: mta:Moth_0537 cell shape determining protein, MreB/Mrl family. (340 aa) |
| | Swol_1642 | KEGG: mta:Moth_0536 DNA repair protein RadC; Belongs to the UPF0758 family. (235 aa) |
| | Swol_1643 | Maf protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. (189 aa) |
| | Swol_1644 | Hypothetical protein. (100 aa) |
| | Swol_1646 | KEGG: chy:CHY_0596 phosphate transporter. (329 aa) |
| | Swol_1647 | KEGG: dsy:DSY3186 hypothetical protein. (211 aa) |
| | Swol_1648 | KEGG: dsy:DSY3187 hypothetical protein; Belongs to the folylpolyglutamate synthase family. (416 aa) |
| | valS | valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. (883 aa) |
| | Swol_1663 | ErfK/YbiS/YcfS/YnhG; KEGG: mta:Moth_0101 ErfK/YbiS/YcfS/YnhG. (283 aa) |
| | Swol_1666 | Hypothetical protein. (96 aa) |
| | Swol_1864 | KEGG: chy:CHY_0730 5-formyltetrahydrofolate cyclo-ligase family protein; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. (194 aa) |
| | lgt | Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family. (253 aa) |
| | tsaD | O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. (357 aa) |
| | Swol_1867 | SSU ribosomal protein S18P alanine acetyltransferase; Acetylates the N-terminal alanine of ribosomal protein S18. (150 aa) |
| | Swol_1868 | Metal-dependent protease-like protein; KEGG: cac:CAC2839 inactive homolog of metal-dependent protease. YDIC B.subtilis ortholog. (238 aa) |
| | Swol_1869 | KEGG: mta:Moth_2160 protein of unknown function UPF0079. (158 aa) |
| | Swol_1870 | Uracil-DNA glycosylase-like protein; KEGG: chy:CHY_0179 uracil-DNA glycosylase, family 4. (233 aa) |
| | Swol_1872 | KEGG: dsy:DSY3978 hypothetical protein. (381 aa) |
| | Swol_1876 | Transcriptional modulator of MazE/toxin, MazF; Toxic component of a type II toxin-antitoxin (TA) system. (109 aa) |
| | Swol_1877 | KEGG: gme:Gmet_2502 transcriptional regulator/antitoxin, MazE. (83 aa) |
| | Swol_1878 | KEGG: dsy:DSY4015 hypothetical protein. (230 aa) |
| | Swol_1879 | Transcriptional modulator of MazE/toxin, MazF; Toxic component of a type II toxin-antitoxin (TA) system. (115 aa) |
| | Swol_1880 | KEGG: mta:Moth_2166 putative transcriptional regulator, CopG family. (89 aa) |
| | Swol_1881 | Hypothetical protein; KEGG: bha:BH3985 transposase (13). (406 aa) |
| | Swol_1882 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. (377 aa) |
| | Swol_1883 | KEGG: pca:Pcar_1004 CBS domain containing membrane protein. (154 aa) |
| | acpS | Phosphopantetheinyl transferase (holo-ACP synthase); Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family. (122 aa) |
| | Swol_1888 | ErfK/YbiS/YcfS/YnhG; KEGG: mta:Moth_0101 ErfK/YbiS/YcfS/YnhG. (332 aa) |
| | Swol_2012 | ABC-type dipeptide transport system periplasmic component-like protein; KEGG: bld:BLi00894 putative oligopeptide ABC transporter (binding protein) (initiation of sporulation, competence development); RBL02204. (545 aa) |
| | Swol_2013 | Secreted protein; Similar to catalytic domain of murein transglycosylase; KEGG: cac:CAC1100 secreted protein, similar to catalytic domain of murein transglycosylase. (187 aa) |
| | coaE | Dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (196 aa) |
| | Swol_2049 | KEGG: tte:TTE0400 uncharacterized membrane protein (homolog of Drosophila rhomboid). (222 aa) |
| | Swol_2099 | Glutamine--fructose-6-phosphate transaminase (isomerizing); KEGG: ctc:CTC02543 D-fructose-6-phosphate amidotransferase. (367 aa) |
| | glmM | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. (450 aa) |
| | Swol_2101 | KEGG: ctc:CTC02547 NAD(FAD)-utilizing dehydrogenase. (546 aa) |
| | Swol_2102 | Conserved hypothetical protein; KEGG: mta:Moth_2247 YbbR-like. (294 aa) |
| | dacA | Protein of unknown function DUF147; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. (288 aa) |
| | Swol_2295 | N-acetylmuramoyl-L-alanine amidase-like protein; KEGG: bld:BLi00171 N-acetylmuramoyl-L-alanine amidase (germination); RBL01082. (259 aa) |
| | Swol_2371 | KEGG: dsy:DSY1838 hypothetical protein. (710 aa) |
| | Swol_2374 | KEGG: mta:Moth_2371 cell shape determining protein, MreB/Mrl family. (342 aa) |
| | murA-2 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (414 aa) |
| | Swol_2406 | Peptidase M23B; KEGG: mta:Moth_2401 peptidase M23B. (283 aa) |
| | Swol_2416 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. (399 aa) |
| | murA-3 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (419 aa) |
| | Swol_2472 | Peptidase M23B; KEGG: mta:Moth_2422 peptidase M23B. (446 aa) |
| | Swol_2473 | KEGG: chy:CHY_2627 radical SAM domain protein. (458 aa) |
| | Swol_2564 | KEGG: tte:TTE0840 hypothetical protein. (131 aa) |
| | Swol_2565 | KEGG: tte:TTE0841 membrane proteins related to metalloendopeptidase. (304 aa) |
