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Swol_1373 Swol_1373 pdxS pdxS Swol_0097 Swol_0097 Swol_0098 Swol_0098 Swol_0099 Swol_0099 panB panB panC panC panD panD Swol_0258 Swol_0258 Swol_0356 Swol_0356 Swol_0421 Swol_0421 Swol_0440 Swol_0440 dxs dxs Swol_0591 Swol_0591 Swol_0639 Swol_0639 thiM thiM thiE thiE thiC thiC Swol_0904 Swol_0904 Swol_0967 Swol_0967 Swol_1020 Swol_1020 Swol_1022 Swol_1022 Swol_1181 Swol_1181 purC purC ribH ribH ribBA ribBA Swol_1221 Swol_1221 Swol_1222 Swol_1222 Swol_1405 Swol_1405 Swol_1526 Swol_1526 Swol_1674 Swol_1674 Swol_2104 Swol_2104 Swol_2165 Swol_2165
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
Swol_1373Precorrin-6B methylase 2-like protein; KEGG: gme:Gmet_0481 precorrin-6y C5,15-methyltransferase, subunit CbiE. (302 aa)
pdxSVitamin B6 biosynthesis protein; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. (294 aa)
Swol_0097KEGG: mta:Moth_0110 dihydropteroate synthase. (412 aa)
Swol_0098Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. (123 aa)
Swol_0099KEGG: xft:PD0186 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase. (164 aa)
panB3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (276 aa)
panCPantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (282 aa)
panDL-aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. (118 aa)
Swol_0258KEGG: gvi:glr0833 hypothetical protein. (268 aa)
Swol_0356cob(I)yrinic acid a,c-diamide adenosyltransferase; KEGG: dsy:DSY1853 cob(I)alamin adenosyltransferase. (187 aa)
Swol_0421KEGG: mmp:MMP0833 hypothetical protein. (307 aa)
Swol_0440Aminotransferase; KEGG: sth:STH768 putative class-III aminotransferase. (891 aa)
dxs1-Deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (638 aa)
Swol_0591KEGG: tte:TTE1305 hypothetical protein. (365 aa)
Swol_0639KEGG: cpe:CPE1338 phosphomethylpyrimidine kinase. (290 aa)
thiMHydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. (266 aa)
thiEThiamine-phosphate diphosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. (209 aa)
thiCThiamine biosynthesis protein thiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. (424 aa)
Swol_0904Riboflavin kinase / FMN adenylyltransferase; KEGG: mta:Moth_1054 riboflavin biosynthesis protein RibF; Belongs to the ribF family. (319 aa)
Swol_0967KEGG: tte:TTE0007 predicted glutamine amidotransferase. (243 aa)
Swol_1020KEGG: tte:TTE1073 Biotin synthase and related enzymes. (311 aa)
Swol_1022KEGG: tte:TTE1568 thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes. (487 aa)
Swol_1181Putative oxidoreductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (307 aa)
purCPhosphoribosylaminoimidazole-succinocarboxamide synthase; KEGG: dsy:DSY0789 hypothetical protein; Belongs to the SAICAR synthetase family. (225 aa)
ribH6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. (141 aa)
ribBAGTP cyclohydrolase II / 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the N-terminal section; belongs to the DHBP synthase family. (398 aa)
Swol_1221KEGG: dsy:DSY1663 riboflavin synthase alpha chain. (226 aa)
Swol_1222Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. (367 aa)
Swol_1405Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; KEGG: cac:CAC1372 cobalamin biosynthesis enzyme CobT. (301 aa)
Swol_1526KEGG: dsy:DSY3492 hypothetical protein. (84 aa)
Swol_1674KEGG: dsy:DSY3831 hypothetical protein. (343 aa)
Swol_2104KEGG: tte:TTE1497 thiamine pyrophosphokinase. (219 aa)
Swol_2165KEGG: tte:TTE0834 hypothetical protein. (303 aa)
Your Current Organism:
Syntrophomonas wolfei Goettingen
NCBI taxonomy Id: 335541
Other names: S. wolfei subsp. wolfei str. Goettingen G311, Syntrophomonas wolfei str. Goettingen, Syntrophomonas wolfei subsp. wolfei Goettingen, Syntrophomonas wolfei subsp. wolfei str. Goettingen, Syntrophomonas wolfei subsp. wolfei str. Goettingen G311, Syntrophomonas wolfei subsp. wolfei str. Gottingen, Syntrophomonas wolfei subsp. wolfei strain Goettingen
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