STRINGSTRING
Swol_0211 Swol_0211 Swol_0380 Swol_0380 Swol_0420 Swol_0420 Swol_0440 Swol_0440 Swol_0559 Swol_0559 folD1 folD1 dxs dxs Swol_0591 Swol_0591 Swol_0639 Swol_0639 thiM thiM thiE thiE Swol_0642 Swol_0642 thiC thiC Swol_0649 Swol_0649 ackA ackA mtnA mtnA metE metE Swol_1319 Swol_1319 Swol_0934 Swol_0934 Swol_1020 Swol_1020 Swol_1022 Swol_1022 metK metK asd asd Swol_2445 Swol_2445 Swol_2356 Swol_2356 Swol_2191 Swol_2191 Swol_2104 Swol_2104 Swol_2059 Swol_2059 Swol_1974 Swol_1974 accD accD accA accA Swol_1674 Swol_1674 Swol_1605 Swol_1605 Swol_1526 Swol_1526 folD2 folD2 Swol_1442 Swol_1442 Swol_1441 Swol_1441 Swol_1438 Swol_1438
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Swol_0211KEGG: par:Psyc_0661 putative LmbE-like protein. (227 aa)
Swol_0380KEGG: aae:aq_1429 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (295 aa)
Swol_0420KEGG: mmp:MMP0832 hypothetical protein. (610 aa)
Swol_0440Aminotransferase; KEGG: sth:STH768 putative class-III aminotransferase. (891 aa)
Swol_0559Biotin carboxylase / acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (449 aa)
folD1Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (277 aa)
dxs1-Deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (638 aa)
Swol_0591KEGG: tte:TTE1305 hypothetical protein. (365 aa)
Swol_0639KEGG: cpe:CPE1338 phosphomethylpyrimidine kinase. (290 aa)
thiMHydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. (266 aa)
thiEThiamine-phosphate diphosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. (209 aa)
Swol_0642KEGG: tte:TTE2448 phosphoserine phosphatase. (215 aa)
thiCThiamine biosynthesis protein thiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. (424 aa)
Swol_0649KEGG: tte:TTE1028 hypothetical protein. (612 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (397 aa)
mtnATranslation initiation factor 2B subunit I family (IF-2BI); Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). (346 aa)
metEMethionine synthase (B12-independent); Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. (758 aa)
Swol_1319KEGG: chy:CHY_1912 homoserine dehydrogenase. (432 aa)
Swol_0934KEGG: cjr:CJE1336 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (287 aa)
Swol_1020KEGG: tte:TTE1073 Biotin synthase and related enzymes. (311 aa)
Swol_1022KEGG: tte:TTE1568 thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes. (487 aa)
metKMethionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (396 aa)
asdAspartate semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (338 aa)
Swol_2445KEGG: par:Psyc_0661 putative LmbE-like protein. (236 aa)
Swol_2356KEGG: chy:CHY_2339 serine acetyltransferase. (240 aa)
Swol_2191Cupin region; KEGG: mta:Moth_1897 cupin region. (122 aa)
Swol_2104KEGG: tte:TTE1497 thiamine pyrophosphokinase. (219 aa)
Swol_2059Gamma-glutamylcysteine synthetase-like protein; KEGG: smu:SMU.1999c hypothetical protein. (479 aa)
Swol_1974KEGG: sth:STH561 lipoate-protein ligase. (332 aa)
accDAcetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (282 aa)
accAAcetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (318 aa)
Swol_1674KEGG: dsy:DSY3831 hypothetical protein. (343 aa)
Swol_1605Cysteine synthase; KEGG: cgb:cg2833 O-acetylserine (thiol)-lyase. (343 aa)
Swol_1526KEGG: dsy:DSY3492 hypothetical protein. (84 aa)
folD2Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (272 aa)
Swol_1442Methionine synthase (B12-dependent); KEGG: pca:Pcar_2722 5-methyltetrahydrofolate-homocysteine methyltransferase, truncation. (839 aa)
Swol_1441KEGG: sat:SYN_01778 hypothetical cytosolic protein. (412 aa)
Swol_1438KEGG: mta:Moth_1706 cysteine synthase A; Belongs to the cysteine synthase/cystathionine beta- synthase family. (305 aa)
Your Current Organism:
Syntrophomonas wolfei Goettingen
NCBI taxonomy Id: 335541
Other names: S. wolfei subsp. wolfei str. Goettingen G311, Syntrophomonas wolfei str. Goettingen, Syntrophomonas wolfei subsp. wolfei Goettingen, Syntrophomonas wolfei subsp. wolfei str. Goettingen, Syntrophomonas wolfei subsp. wolfei str. Goettingen G311, Syntrophomonas wolfei subsp. wolfei str. Gottingen, Syntrophomonas wolfei subsp. wolfei strain Goettingen
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