(43 nodes) Mixed, incl. P-body, and Eukaryotic translation initiation factor 4F complex network (Zymoseptoria tritici IPO323)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	F9WWQ0_ZYMTI	ATP-dependent (S)-NAD(P)H-hydrate dehydratase; Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ATP, which is converted to ADP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S-and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Belongs to the NnrD/CARKD family. (327 aa)
	F9WY00_ZYMTI	Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family. (252 aa)
	F9WZV5_ZYMTI	Uncharacterized protein. (625 aa)
	F9X0L2_ZYMTI	Nudix hydrolase domain-containing protein; Belongs to the Nudix hydrolase family. (165 aa)
	F9X1I9_ZYMTI	Uncharacterized protein. (378 aa)
	F9X203_ZYMTI	Uncharacterized protein. (2296 aa)
	F9X266_ZYMTI	Uncharacterized protein. (590 aa)
	F9X292_ZYMTI	Pan3_PK domain-containing protein. (482 aa)
	F9X2W6_ZYMTI	Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family. (269 aa)
	F9X3H5_ZYMTI	Nudix hydrolase domain-containing protein. (468 aa)
	F9X3I6_ZYMTI	Uncharacterized protein. (557 aa)
	F9X3R2_ZYMTI	Uncharacterized protein. (486 aa)
	F9X3X9_ZYMTI	Uncharacterized protein. (1130 aa)
	F9X4G5_ZYMTI	NTP_transf_9 domain-containing protein. (150 aa)
	F9X4R8_ZYMTI	Uncharacterized protein. (173 aa)
	F9X645_ZYMTI	Uncharacterized protein. (763 aa)
	F9X671_ZYMTI	Uncharacterized protein. (1301 aa)
	F9X686_ZYMTI	Uncharacterized protein. (677 aa)
	F9X6Y2_ZYMTI	MIF4G domain-containing protein. (676 aa)
	F9X7R8_ZYMTI	Nudix hydrolase domain-containing protein. (295 aa)
	MOT2	General negative regulator of transcription subunit 4. (1473 aa)
	F9X9T7_ZYMTI	NAD(P)H-hydrate epimerase; Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX. (237 aa)
	PAN2	PAN2-PAN3 deadenylation complex catalytic subunit PAN2; Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1. PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent [...] (1147 aa)
	F9XB82_ZYMTI	Nudix hydrolase domain-containing protein. (197 aa)
	F9XCK4_ZYMTI	Uncharacterized protein. (480 aa)
	F9XCM4_ZYMTI	NOT2_3_5 domain-containing protein. (175 aa)
	F9XCM5_ZYMTI	CUE domain-containing protein. (188 aa)
	F9XGG6_ZYMTI	Uncharacterized protein. (68 aa)
	F9XHI4_ZYMTI	Uncharacterized protein. (364 aa)
	F9XHI5_ZYMTI	Uncharacterized protein. (335 aa)
	F9XHM0_ZYMTI	Uncharacterized protein. (300 aa)
	F9XHV9_ZYMTI	Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family. (354 aa)
	F9XIF9_ZYMTI	Uncharacterized protein. (337 aa)
	F9XIW6_ZYMTI	Nudix hydrolase domain-containing protein. (322 aa)
	F9XJM2_ZYMTI	Uncharacterized protein. (353 aa)
	F9XKR2_ZYMTI	Uncharacterized protein. (458 aa)
	F9XLF2_ZYMTI	Nudix hydrolase domain-containing protein. (256 aa)
	F9XMC1_ZYMTI	Uncharacterized protein. (838 aa)
	F9XN89_ZYMTI	Uncharacterized protein; Belongs to the DEAD box helicase family. (504 aa)
	F9XNA8_ZYMTI	Endo/exonuclease/phosphatase domain-containing protein. (692 aa)
	F9XNW4_ZYMTI	Uncharacterized protein. (464 aa)
	F9XP10_ZYMTI	Uncharacterized protein. (307 aa)
	F9XRE3_ZYMTI	Uncharacterized protein. (171 aa)

Your Current Organism:

Zymoseptoria tritici IPO323

NCBI taxonomy Id: 336722
Other names: Mycosphaerella graminicola IPO323, Z. tritici IPO323

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
F9WWQ0_ZYMTI	F9X4R8_ZYMTI	F9WWQ0	F9X4R8	ATP-dependent (S)-NAD(P)H-hydrate dehydratase; Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ATP, which is converted to ADP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S-and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Belongs to the NnrD/CARKD family.	Uncharacterized protein.	0.841
F9WWQ0_ZYMTI	F9X9T7_ZYMTI	F9WWQ0	F9X9T7	ATP-dependent (S)-NAD(P)H-hydrate dehydratase; Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ATP, which is converted to ADP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S-and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Belongs to the NnrD/CARKD family.	NAD(P)H-hydrate epimerase; Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.	0.918
F9WY00_ZYMTI	F9X266_ZYMTI	F9WY00	F9X266	Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family.	Uncharacterized protein.	0.625
F9WY00_ZYMTI	F9X292_ZYMTI	F9WY00	F9X292	Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family.	Pan3_PK domain-containing protein.	0.579
F9WY00_ZYMTI	F9X3R2_ZYMTI	F9WY00	F9X3R2	Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family.	Uncharacterized protein.	0.452
F9WY00_ZYMTI	F9X4R8_ZYMTI	F9WY00	F9X4R8	Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family.	Uncharacterized protein.	0.609
F9WY00_ZYMTI	F9X645_ZYMTI	F9WY00	F9X645	Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family.	Uncharacterized protein.	0.964
F9WY00_ZYMTI	F9X671_ZYMTI	F9WY00	F9X671	Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family.	Uncharacterized protein.	0.613
F9WY00_ZYMTI	F9X686_ZYMTI	F9WY00	F9X686	Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family.	Uncharacterized protein.	0.473
F9WY00_ZYMTI	F9X6Y2_ZYMTI	F9WY00	F9X6Y2	Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family.	MIF4G domain-containing protein.	0.990
F9WY00_ZYMTI	F9XGG6_ZYMTI	F9WY00	F9XGG6	Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family.	Uncharacterized protein.	0.613
F9WY00_ZYMTI	F9XHI4_ZYMTI	F9WY00	F9XHI4	Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family.	Uncharacterized protein.	0.481
F9WY00_ZYMTI	F9XHI5_ZYMTI	F9WY00	F9XHI5	Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family.	Uncharacterized protein.	0.481
F9WY00_ZYMTI	F9XHV9_ZYMTI	F9WY00	F9XHV9	Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family.	Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family.	0.906
F9WY00_ZYMTI	F9XIF9_ZYMTI	F9WY00	F9XIF9	Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family.	Uncharacterized protein.	0.483
F9WY00_ZYMTI	F9XLF2_ZYMTI	F9WY00	F9XLF2	Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family.	Nudix hydrolase domain-containing protein.	0.551
F9WY00_ZYMTI	F9XMC1_ZYMTI	F9WY00	F9XMC1	Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family.	Uncharacterized protein.	0.505
F9WY00_ZYMTI	F9XN89_ZYMTI	F9WY00	F9XN89	Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family.	Uncharacterized protein; Belongs to the DEAD box helicase family.	0.803
F9WY00_ZYMTI	F9XNA8_ZYMTI	F9WY00	F9XNA8	Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family.	Endo/exonuclease/phosphatase domain-containing protein.	0.543
F9WY00_ZYMTI	PAN2	F9WY00	F9XAV1	Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family.	PAN2-PAN3 deadenylation complex catalytic subunit PAN2; Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1. PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent [...]	0.580