(18 nodes) RNA polymerase II, core complex, and Cdc73/Paf1 complex network (Zymoseptoria tritici IPO323)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PAFD2401	Paf1p complex subunit. (601 aa)
	F9WWV9_ZYMTI	RPOLD domain-containing protein. (361 aa)
	F9WYC4_ZYMTI	S1 motif domain-containing protein. (167 aa)
	F9X075_ZYMTI	RPOL4c domain-containing protein. (159 aa)
	F9X1N4_ZYMTI	Uncharacterized protein. (385 aa)
	PAFA2401	Paf1 complex protein. (451 aa)
	F9X7U2_ZYMTI	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (139 aa)
	F9X858_ZYMTI	FACT complex subunit POB3; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of [...] (560 aa)
	F9X8C0_ZYMTI	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1231 aa)
	F9X8Y2_ZYMTI	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1773 aa)
	GTA2401	Transcription elongation factor SPT5; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene. (987 aa)
	F9XBT7_ZYMTI	Uncharacterized protein. (314 aa)
	PAFE2401	Paf1p complex subunit. (418 aa)
	F9XF11_ZYMTI	RNA_pol_L_2 domain-containing protein. (121 aa)
	PAFC2401	Paf1p complex subunit. (1216 aa)
	F9XIW5_ZYMTI	DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (142 aa)
	GTG2401	Transcription elongation factor SPT4; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene. (115 aa)
	GTC2401	FACT complex protein. (1029 aa)

Your Current Organism:

Zymoseptoria tritici IPO323

NCBI taxonomy Id: 336722
Other names: Mycosphaerella graminicola IPO323, Z. tritici IPO323

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
F9WWV9_ZYMTI	F9WYC4_ZYMTI	F9WWV9	F9WYC4	RPOLD domain-containing protein.	S1 motif domain-containing protein.	0.999
F9WWV9_ZYMTI	F9X075_ZYMTI	F9WWV9	F9X075	RPOLD domain-containing protein.	RPOL4c domain-containing protein.	0.999
F9WWV9_ZYMTI	F9X1N4_ZYMTI	F9WWV9	F9X1N4	RPOLD domain-containing protein.	Uncharacterized protein.	0.917
F9WWV9_ZYMTI	F9X7U2_ZYMTI	F9WWV9	F9X7U2	RPOLD domain-containing protein.	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.	0.999
F9WWV9_ZYMTI	F9X858_ZYMTI	F9WWV9	F9X858	RPOLD domain-containing protein.	FACT complex subunit POB3; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of [...]	0.965
F9WWV9_ZYMTI	F9X8C0_ZYMTI	F9WWV9	F9X8C0	RPOLD domain-containing protein.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.999
F9WWV9_ZYMTI	F9X8Y2_ZYMTI	F9WWV9	F9X8Y2	RPOLD domain-containing protein.	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.999
F9WWV9_ZYMTI	F9XBT7_ZYMTI	F9WWV9	F9XBT7	RPOLD domain-containing protein.	Uncharacterized protein.	0.996
F9WWV9_ZYMTI	F9XF11_ZYMTI	F9WWV9	F9XF11	RPOLD domain-containing protein.	RNA_pol_L_2 domain-containing protein.	0.999
F9WWV9_ZYMTI	F9XIW5_ZYMTI	F9WWV9	F9XIW5	RPOLD domain-containing protein.	DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively.	0.999
F9WWV9_ZYMTI	GTA2401	F9WWV9	F9XBA2	RPOLD domain-containing protein.	Transcription elongation factor SPT5; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene.	0.998
F9WWV9_ZYMTI	GTC2401	F9WWV9	F9XPS1	RPOLD domain-containing protein.	FACT complex protein.	0.984
F9WWV9_ZYMTI	GTG2401	F9WWV9	F9XKP8	RPOLD domain-containing protein.	Transcription elongation factor SPT4; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene.	0.997
F9WWV9_ZYMTI	PAFA2401	F9WWV9	F9X5E1	RPOLD domain-containing protein.	Paf1 complex protein.	0.942
F9WWV9_ZYMTI	PAFC2401	F9WWV9	F9XGW9	RPOLD domain-containing protein.	Paf1p complex subunit.	0.952
F9WWV9_ZYMTI	PAFD2401	F9WWV9	F9WW96	RPOLD domain-containing protein.	Paf1p complex subunit.	0.939
F9WWV9_ZYMTI	PAFE2401	F9WWV9	F9XCD4	RPOLD domain-containing protein.	Paf1p complex subunit.	0.910
F9WYC4_ZYMTI	F9WWV9_ZYMTI	F9WYC4	F9WWV9	S1 motif domain-containing protein.	RPOLD domain-containing protein.	0.999
F9WYC4_ZYMTI	F9X075_ZYMTI	F9WYC4	F9X075	S1 motif domain-containing protein.	RPOL4c domain-containing protein.	0.999
F9WYC4_ZYMTI	F9X1N4_ZYMTI	F9WYC4	F9X1N4	S1 motif domain-containing protein.	Uncharacterized protein.	0.740