(29 nodes) Nuclear DNA replication network (Zymoseptoria tritici IPO323)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	F9X0R2_ZYMTI	Sld5 domain-containing protein. (222 aa)
	F9X6L9_ZYMTI	Rtf2 domain-containing protein. (291 aa)
	F9X6T1_ZYMTI	Sld5 domain-containing protein. (177 aa)
	F9X798_ZYMTI	DNA polymerase. (1478 aa)
	F9X7D3_ZYMTI	Uncharacterized protein. (199 aa)
	F9X8J2_ZYMTI	Uncharacterized protein. (942 aa)
	F9X8J8_ZYMTI	ORC_WH_C domain-containing protein. (668 aa)
	F9X8P1_ZYMTI	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (259 aa)
	F9X8P4_ZYMTI	Vezatin domain-containing protein. (560 aa)
	NFB2401	Chromatin assembly complex 1 subunit B/CAC2. (740 aa)
	F9XBA1_ZYMTI	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (636 aa)
	F9XBH6_ZYMTI	Uncharacterized protein. (826 aa)
	F9XDM6_ZYMTI	Uncharacterized protein. (472 aa)
	CDC7	Protein kinase domain-containing protein. (427 aa)
	F9XDX0_ZYMTI	DNA helicase; Belongs to the MCM family. (1043 aa)
	F9XE61_ZYMTI	DNA helicase; Belongs to the MCM family. (887 aa)
	MCM7	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (757 aa)
	F9XG39_ZYMTI	AAA domain-containing protein. (511 aa)
	F9XHQ3_ZYMTI	Uncharacterized protein. (424 aa)
	F9XI38_ZYMTI	Uncharacterized protein. (504 aa)
	F9XIR4_ZYMTI	DNA helicase; Belongs to the MCM family. (732 aa)
	F9XIU6_ZYMTI	DNA helicase; Belongs to the MCM family. (951 aa)
	F9XJR4_ZYMTI	CBFD_NFYB_HMF domain-containing protein. (113 aa)
	MgPTP1	Tyrosine protein phosphatase 1. (724 aa)
	F9XL71_ZYMTI	DNA helicase; Belongs to the MCM family. (889 aa)
	F9XL87_ZYMTI	Uncharacterized protein. (577 aa)
	F9XLH8_ZYMTI	AAA_16 domain-containing protein. (458 aa)
	F9XS64_ZYMTI	Uncharacterized protein. (137 aa)
	F9WX56_ZYMTI	DNA ligase. (884 aa)

Your Current Organism:

Zymoseptoria tritici IPO323

NCBI taxonomy Id: 336722
Other names: Mycosphaerella graminicola IPO323, Z. tritici IPO323

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDC7	F9X798_ZYMTI	F9XDT1	F9X798	Protein kinase domain-containing protein.	DNA polymerase.	0.461
CDC7	F9X7D3_ZYMTI	F9XDT1	F9X7D3	Protein kinase domain-containing protein.	Uncharacterized protein.	0.461
CDC7	F9X8J2_ZYMTI	F9XDT1	F9X8J2	Protein kinase domain-containing protein.	Uncharacterized protein.	0.807
CDC7	F9X8J8_ZYMTI	F9XDT1	F9X8J8	Protein kinase domain-containing protein.	ORC_WH_C domain-containing protein.	0.679
CDC7	F9XBH6_ZYMTI	F9XDT1	F9XBH6	Protein kinase domain-containing protein.	Uncharacterized protein.	0.716
CDC7	F9XDX0_ZYMTI	F9XDT1	F9XDX0	Protein kinase domain-containing protein.	DNA helicase; Belongs to the MCM family.	0.994
CDC7	F9XE61_ZYMTI	F9XDT1	F9XE61	Protein kinase domain-containing protein.	DNA helicase; Belongs to the MCM family.	0.994
CDC7	F9XG39_ZYMTI	F9XDT1	F9XG39	Protein kinase domain-containing protein.	AAA domain-containing protein.	0.767
CDC7	F9XI38_ZYMTI	F9XDT1	F9XI38	Protein kinase domain-containing protein.	Uncharacterized protein.	0.744
CDC7	F9XIR4_ZYMTI	F9XDT1	F9XIR4	Protein kinase domain-containing protein.	DNA helicase; Belongs to the MCM family.	0.994
CDC7	F9XIU6_ZYMTI	F9XDT1	F9XIU6	Protein kinase domain-containing protein.	DNA helicase; Belongs to the MCM family.	0.994
CDC7	F9XL71_ZYMTI	F9XDT1	F9XL71	Protein kinase domain-containing protein.	DNA helicase; Belongs to the MCM family.	0.994
CDC7	F9XLH8_ZYMTI	F9XDT1	F9XLH8	Protein kinase domain-containing protein.	AAA_16 domain-containing protein.	0.807
CDC7	MCM7	F9XDT1	F9XFU5	Protein kinase domain-containing protein.	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	0.993
F9WX56_ZYMTI	F9X798_ZYMTI	F9WX56	F9X798	DNA ligase.	DNA polymerase.	0.704
F9WX56_ZYMTI	F9X7D3_ZYMTI	F9WX56	F9X7D3	DNA ligase.	Uncharacterized protein.	0.600
F9WX56_ZYMTI	F9X8J2_ZYMTI	F9WX56	F9X8J2	DNA ligase.	Uncharacterized protein.	0.590
F9WX56_ZYMTI	F9X8P1_ZYMTI	F9WX56	F9X8P1	DNA ligase.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.926
F9WX56_ZYMTI	F9X8P4_ZYMTI	F9WX56	F9X8P4	DNA ligase.	Vezatin domain-containing protein.	0.926
F9WX56_ZYMTI	F9XDX0_ZYMTI	F9WX56	F9XDX0	DNA ligase.	DNA helicase; Belongs to the MCM family.	0.677