Groups of genes that are frequently observed in each other's genomic neighborhood.
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Databases
Known metabolic pathways, protein complexes, signal transduction pathways, etc ... from curated databases.
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Fusion
Genes that are sometimes fused into single open reading frames.
STRING allows inspection of the interaction evidence for any given network. Choose any of the viewers above (disabled if not applicable in your network).
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes: query proteins and first shell of interactors
white nodes: second shell of interactors
Node Content
empty nodes: proteins of unknown 3D structure
filled nodes: a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
F9X256_ZYMTI
RING-type domain-containing protein. (817 aa)
F9X9A1_ZYMTI
DUF1746 domain-containing protein. (1070 aa)
F9X6T2_ZYMTI
Uncharacterized protein. (269 aa)
F9X291_ZYMTI
UBX domain-containing protein. (512 aa)
Your Current Organism:
Zymoseptoria tritici IPO323
NCBI taxonomy Id: 336722 Other names: Mycosphaerella graminicola IPO323, Z. tritici IPO323