(59 nodes) Nuclear DNA-directed RNA polymerase complex network (Zymoseptoria tritici IPO323)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	F9WZ53_ZYMTI	Uncharacterized protein. (291 aa)
	F9WW52_ZYMTI	Uncharacterized protein. (72 aa)
	PAFD2401	Paf1p complex subunit. (601 aa)
	F9WWV9_ZYMTI	RPOLD domain-containing protein. (361 aa)
	F9WXB6_ZYMTI	DNA-directed RNA polymerase III subunit RPC6; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs; Belongs to the eukaryotic RPC34/RPC39 RNA polymerase subunit family. (349 aa)
	F9WXU8_ZYMTI	Uncharacterized protein. (275 aa)
	HAF2401	Transcription initiation factor TFIID, subunit TAF1. (1044 aa)
	F9WYG0_ZYMTI	BTP domain-containing protein. (224 aa)
	F9WZ77_ZYMTI	Uncharacterized protein. (108 aa)
	F9WZG7_ZYMTI	Uncharacterized protein. (424 aa)
	F9X084_ZYMTI	UmuC domain-containing protein. (596 aa)
	F9X0P7_ZYMTI	Uncharacterized protein. (367 aa)
	POLX1	DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. (590 aa)
	F9X1A9_ZYMTI	Uncharacterized protein. (88 aa)
	F9X1D7_ZYMTI	TAFII55_N domain-containing protein. (526 aa)
	F9X1N4_ZYMTI	Uncharacterized protein. (385 aa)
	F9X1T4_ZYMTI	Uncharacterized protein. (638 aa)
	F9X2P4_ZYMTI	Uncharacterized protein. (234 aa)
	F9X3H2_ZYMTI	General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family. (445 aa)
	F9X3R3_ZYMTI	Uncharacterized protein. (323 aa)
	F9X491_ZYMTI	DUF4211 domain-containing protein. (506 aa)
	F9X4T0_ZYMTI	DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (672 aa)
	F9X5D9_ZYMTI	Uncharacterized protein. (601 aa)
	PAFA2401	Paf1 complex protein. (451 aa)
	F9X6C0_ZYMTI	HTH TFE/IIEalpha-type domain-containing protein. (404 aa)
	F9X6L5_ZYMTI	RNA polymerase II transcription factor B subunit 2; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (493 aa)
	F9X6Q8_ZYMTI	Uncharacterized protein. (240 aa)
	F9X734_ZYMTI	BSD domain-containing protein. (640 aa)
	F9X798_ZYMTI	DNA polymerase. (1478 aa)
	F9X7D3_ZYMTI	Uncharacterized protein. (199 aa)
	F9X802_ZYMTI	Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase. (287 aa)
	F9X8B6_ZYMTI	Uncharacterized protein. (280 aa)
	F9X914_ZYMTI	DNA primase large subunit; DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication; Belongs to the eukaryotic-type primase large subunit family. (510 aa)
	F9XA01_ZYMTI	RING-type domain-containing protein. (321 aa)
	F9XB61_ZYMTI	Uncharacterized protein. (1180 aa)
	F9XB93_ZYMTI	Uncharacterized protein. (231 aa)
	F9XBY9_ZYMTI	RPOLD domain-containing protein. (474 aa)
	PAFE2401	Paf1p complex subunit. (418 aa)
	F9XDH6_ZYMTI	Uncharacterized protein. (218 aa)
	F9XDI8_ZYMTI	TFA2_Winged_2 domain-containing protein. (245 aa)
	F9XE91_ZYMTI	TFIID_20kDa domain-containing protein. (135 aa)
	F9XF11_ZYMTI	RNA_pol_L_2 domain-containing protein. (121 aa)
	KIN28	Serine/threonine protein kinase, CMGC family, CDC2/CDK subfamily; Belongs to the protein kinase superfamily. (379 aa)
	F9XG12_ZYMTI	Uncharacterized protein; Belongs to the peptidase M18 family. (518 aa)
	PAFC2401	Paf1p complex subunit. (1216 aa)
	F9XGZ8_ZYMTI	TAF domain-containing protein. (449 aa)
	F9XH99_ZYMTI	CYCLIN domain-containing protein; Belongs to the cyclin family. (363 aa)
	F9XHQ7_ZYMTI	Uncharacterized protein. (853 aa)
	F9XIJ4_ZYMTI	RNA_pol_L_2 domain-containing protein. (101 aa)
	F9XIW5_ZYMTI	DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (142 aa)
	F9XJB2_ZYMTI	Transcription initiation factor TFIID subunit 10; Functions as a component of the DNA-binding general transcription factor complex TFIID and the transcription regulatory histone acetylation (HAT) complexes SAGA and SLIK. Binding of TFIID to a promoter (with or without TATA element) is the initial step in preinitiation complex (PIC) formation. TFIID plays a key role in the regulation of gene expression by RNA polymerase II through different activities such as transcription activator interaction, core promoter recognition and selectivity, TFIIA and TFIIB interaction, chromatin modificati [...] (195 aa)
	F9XJM7_ZYMTI	Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family. (114 aa)
	F9XK39_ZYMTI	Protein kinase domain-containing protein. (341 aa)
	F9XKC4_ZYMTI	Uncharacterized protein. (386 aa)
	F9XLI8_ZYMTI	RNA polymerase III subunit C3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (648 aa)
	TAFV2401	Transcription initiation factor TFIID, subunit TAF5. (733 aa)
	F9XMH4_ZYMTI	Uncharacterized protein. (429 aa)
	F9XP73_ZYMTI	Uncharacterized protein. (144 aa)
	F9XPB5_ZYMTI	WD_REPEATS_REGION domain-containing protein. (379 aa)

Your Current Organism:

Zymoseptoria tritici IPO323

NCBI taxonomy Id: 336722
Other names: Mycosphaerella graminicola IPO323, Z. tritici IPO323

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
F9WW52_ZYMTI	F9WWV9_ZYMTI	F9WW52	F9WWV9	Uncharacterized protein.	RPOLD domain-containing protein.	0.950
F9WW52_ZYMTI	F9WXU8_ZYMTI	F9WW52	F9WXU8	Uncharacterized protein.	Uncharacterized protein.	0.803
F9WW52_ZYMTI	F9WZ77_ZYMTI	F9WW52	F9WZ77	Uncharacterized protein.	Uncharacterized protein.	0.948
F9WW52_ZYMTI	F9WZG7_ZYMTI	F9WW52	F9WZG7	Uncharacterized protein.	Uncharacterized protein.	0.878
F9WW52_ZYMTI	F9X0P7_ZYMTI	F9WW52	F9X0P7	Uncharacterized protein.	Uncharacterized protein.	0.980
F9WW52_ZYMTI	F9X1A9_ZYMTI	F9WW52	F9X1A9	Uncharacterized protein.	Uncharacterized protein.	0.948
F9WW52_ZYMTI	F9X1D7_ZYMTI	F9WW52	F9X1D7	Uncharacterized protein.	TAFII55_N domain-containing protein.	0.785
F9WW52_ZYMTI	F9X3H2_ZYMTI	F9WW52	F9X3H2	Uncharacterized protein.	General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family.	0.969
F9WW52_ZYMTI	F9X3R3_ZYMTI	F9WW52	F9X3R3	Uncharacterized protein.	Uncharacterized protein.	0.969
F9WW52_ZYMTI	F9X491_ZYMTI	F9WW52	F9X491	Uncharacterized protein.	DUF4211 domain-containing protein.	0.654
F9WW52_ZYMTI	F9X6C0_ZYMTI	F9WW52	F9X6C0	Uncharacterized protein.	HTH TFE/IIEalpha-type domain-containing protein.	0.978
F9WW52_ZYMTI	F9X6L5_ZYMTI	F9WW52	F9X6L5	Uncharacterized protein.	RNA polymerase II transcription factor B subunit 2; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family.	0.968
F9WW52_ZYMTI	F9X6Q8_ZYMTI	F9WW52	F9X6Q8	Uncharacterized protein.	Uncharacterized protein.	0.803
F9WW52_ZYMTI	F9X734_ZYMTI	F9WW52	F9X734	Uncharacterized protein.	BSD domain-containing protein.	0.951
F9WW52_ZYMTI	F9X802_ZYMTI	F9WW52	F9X802	Uncharacterized protein.	Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.	0.912
F9WW52_ZYMTI	F9XA01_ZYMTI	F9WW52	F9XA01	Uncharacterized protein.	RING-type domain-containing protein.	0.951
F9WW52_ZYMTI	F9XB61_ZYMTI	F9WW52	F9XB61	Uncharacterized protein.	Uncharacterized protein.	0.817
F9WW52_ZYMTI	F9XB93_ZYMTI	F9WW52	F9XB93	Uncharacterized protein.	Uncharacterized protein.	0.654
F9WW52_ZYMTI	F9XBY9_ZYMTI	F9WW52	F9XBY9	Uncharacterized protein.	RPOLD domain-containing protein.	0.853
F9WW52_ZYMTI	F9XDH6_ZYMTI	F9WW52	F9XDH6	Uncharacterized protein.	Uncharacterized protein.	0.950