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DUSP6 DUSP6 CREM CREM JUNB JUNB SPAG9 SPAG9 MAPK11 MAPK11 MAP2K7 MAP2K7 MAP3K2 MAP3K2 ATF3 ATF3 LOC105507704 LOC105507704 MAFB MAFB CEBPG CEBPG ERN2 ERN2 ATF2 ATF2 MAPK6 MAPK6 MAPKAPK5 MAPKAPK5 MAFF MAFF MAP3K6 MAP3K6 DUSP7 DUSP7 ENSCANP00000006830 ENSCANP00000006830 MAP2K6 MAP2K6 ELK1 ELK1 ENSCANP00000007060 ENSCANP00000007060 ATF1 ATF1 CAMK1D CAMK1D JDP2 JDP2 MAP3K3 MAP3K3 ELK3 ELK3 CAMK1G CAMK1G MAP3K15 MAP3K15 BACH2 BACH2 MAPK9 MAPK9 BACH1 BACH1 CREB5 CREB5 FOSL2 FOSL2 CREB1 CREB1 MAPK12 MAPK12 DUSP16 DUSP16 MAFG MAFG NFE2L2 NFE2L2 ENSCANP00000015510 ENSCANP00000015510 MAPK3 MAPK3 COIL COIL DAB2IP DAB2IP MAP3K20 MAP3K20 MAP2K3 MAP2K3 DUSP4 DUSP4 SMYD3 SMYD3 ERN1 ERN1 MAPK10 MAPK10 CLIC3 CLIC3 FOS FOS DDIT3 DDIT3 MAPK8 MAPK8 MAP2K4 MAP2K4 ARL4C ARL4C XBP1 XBP1 CRTC2 CRTC2 MAPK8IP2 MAPK8IP2 ENSCANP00000024565 ENSCANP00000024565 MAP2K5 MAP2K5 MAP3K5 MAP3K5 ATF6 ATF6 MAPKAPK3 MAPKAPK3 PEA15 PEA15 MAP3K1 MAP3K1 MAPK8IP3 MAPK8IP3 SRF SRF CREB3L4 CREB3L4 ELK4 ELK4 NFE2 NFE2 MAPK15 MAPK15 MAF MAF LOC105518702 LOC105518702 CREB3L1 CREB3L1 MAPK8IP1 MAPK8IP1 NEURL4 NEURL4 MAPK4 MAPK4 ATF4 ATF4 JUN JUN DUSP9 DUSP9 DUSP8 DUSP8 MAPK13 MAPK13 FOSL1 FOSL1 MAPKAPK2 MAPKAPK2 ATF6B ATF6B MAP3K11 MAP3K11 CREB3L2 CREB3L2 MAFK MAFK ENSCANP00000035578 ENSCANP00000035578 FOSB FOSB CREB3 CREB3 KEAP1 KEAP1 ATF7 ATF7 CREB3L3 CREB3L3 TRAF4 TRAF4 NFE2L1 NFE2L1 RPS6KA4 RPS6KA4 RPS6KA5 RPS6KA5 MAPK14 MAPK14 DUSP10 DUSP10
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
DUSP6Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (381 aa)
CREMcAMP responsive element modulator. (322 aa)
JUNBJunB proto-oncogene, AP-1 transcription factor subunit. (347 aa)
SPAG9Sperm associated antigen 9. (1339 aa)
MAPK11Mitogen-activated protein kinase. (306 aa)
MAP2K7Mitogen-activated protein kinase kinase 7. (468 aa)
MAP3K2Mitogen-activated protein kinase kinase kinase 2. (639 aa)
ATF3Activating transcription factor 3. (181 aa)
LOC105507704ETS domain-containing protein. (403 aa)
MAFBMAF bZIP transcription factor B. (323 aa)
CEBPGCCAAT enhancer binding protein gamma. (150 aa)
ERN2Endoplasmic reticulum to nucleus signaling 2. (926 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa)
MAPK6Mitogen-activated protein kinase 6. (721 aa)
MAPKAPK5MAPK activated protein kinase 5. (481 aa)
MAFFMAF bZIP transcription factor F. (164 aa)
MAP3K6Mitogen-activated protein kinase kinase kinase 6. (1233 aa)
DUSP7Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (373 aa)
ENSCANP00000006830Protein kinase domain-containing protein. (373 aa)
MAP2K6Mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (334 aa)
ELK1ETS domain-containing protein. (428 aa)
ENSCANP00000007060Protein kinase domain-containing protein. (587 aa)
ATF1Activating transcription factor 1. (270 aa)
CAMK1DCalcium/calmodulin dependent protein kinase ID. (354 aa)
JDP2Jun dimerization protein 2. (174 aa)
MAP3K3Mitogen-activated protein kinase kinase kinase 3. (657 aa)
ELK3ETS transcription factor ELK3. (407 aa)
CAMK1GCalcium/calmodulin dependent protein kinase IG; Belongs to the protein kinase superfamily. (476 aa)
MAP3K15Mitogen-activated protein kinase kinase kinase 15. (1202 aa)
BACH2BTB domain and CNC homolog 2. (842 aa)
MAPK9Mitogen-activated protein kinase. (399 aa)
BACH1BTB domain and CNC homolog 1. (736 aa)
CREB5Cyclic AMP-responsive element-binding protein 5; Binds to the cAMP response element and activates transcription. (508 aa)
FOSL2FOS like 2, AP-1 transcription factor subunit. (309 aa)
CREB1cAMP responsive element binding protein 1. (341 aa)
MAPK12Mitogen-activated protein kinase. (325 aa)
DUSP16Dual specificity phosphatase 16. (664 aa)
MAFGMAF bZIP transcription factor G. (162 aa)
NFE2L2Nuclear factor, erythroid 2 like 2. (601 aa)
ENSCANP00000015510HSF_DOMAIN domain-containing protein. (330 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (380 aa)
COILCoilin. (575 aa)
DAB2IPDAB2 interacting protein. (1155 aa)
MAP3K20Mitogen-activated protein kinase kinase kinase 20. (800 aa)
MAP2K3Mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily. (347 aa)
DUSP4Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (394 aa)
SMYD3SET and MYND domain containing 3. (405 aa)
ERN1Endoplasmic reticulum to nucleus signaling 1. (979 aa)
MAPK10Mitogen-activated protein kinase. (550 aa)
CLIC3Chloride intracellular channel protein; Belongs to the chloride channel CLIC family. (236 aa)
FOSFos proto-oncogene, AP-1 transcription factor subunit. (380 aa)
DDIT3DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] (169 aa)
MAPK8Mitogen-activated protein kinase. (427 aa)
MAP2K4Mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily. (373 aa)
ARL4CADP ribosylation factor like GTPase 4C; Belongs to the small GTPase superfamily. Arf family. (202 aa)
XBP1X-box binding protein 1. (204 aa)
CRTC2CREB regulated transcription coactivator 2. (694 aa)
MAPK8IP2PID domain-containing protein. (178 aa)
ENSCANP00000024565Protein kinase domain-containing protein. (346 aa)
MAP2K5Mitogen-activated protein kinase kinase 5; Belongs to the protein kinase superfamily. (448 aa)
MAP3K5Mitogen-activated protein kinase kinase kinase 5. (1364 aa)
ATF6Activating transcription factor 6. (669 aa)
MAPKAPK3MAPK activated protein kinase 3; Belongs to the protein kinase superfamily. (382 aa)
PEA15Proliferation and apoptosis adaptor protein 15. (151 aa)
MAP3K1Mitogen-activated protein kinase kinase kinase 1. (1356 aa)
MAPK8IP3Mitogen-activated protein kinase 8 interacting protein 3. (1344 aa)
SRFSerum response factor. (406 aa)
CREB3L4cAMP responsive element binding protein 3 like 4. (427 aa)
ELK4ETS transcription factor ELK4. (431 aa)
NFE2Nuclear factor, erythroid 2. (373 aa)
MAPK15Mitogen-activated protein kinase. (545 aa)
MAFMAF bZIP transcription factor; Belongs to the bZIP family. (301 aa)
LOC105518702Protein kinase domain-containing protein. (591 aa)
CREB3L1cAMP responsive element binding protein 3 like 1. (519 aa)
MAPK8IP1Mitogen-activated protein kinase 8 interacting protein 1. (614 aa)
NEURL4Neuralized E3 ubiquitin protein ligase 4. (1564 aa)
MAPK4Mitogen-activated protein kinase 4. (587 aa)
ATF4Activating transcription factor 4. (351 aa)
JUNJun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (246 aa)
DUSP9Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (385 aa)
DUSP8Dual specificity phosphatase 8. (416 aa)
MAPK13Mitogen-activated protein kinase. (491 aa)
FOSL1FOS like 1, AP-1 transcription factor subunit. (271 aa)
MAPKAPK2MAPK activated protein kinase 2; Belongs to the protein kinase superfamily. (431 aa)
ATF6BActivating transcription factor 6 beta. (690 aa)
MAP3K11Mitogen-activated protein kinase kinase kinase. (847 aa)
CREB3L2cAMP responsive element binding protein 3 like 2. (461 aa)
MAFKMAF bZIP transcription factor K. (155 aa)
ENSCANP00000035578Uncharacterized protein. (482 aa)
FOSBFosB proto-oncogene, AP-1 transcription factor subunit. (338 aa)
CREB3cAMP responsive element binding protein 3. (372 aa)
KEAP1Kelch like ECH associated protein 1. (624 aa)
ATF7Cyclic AMP-dependent transcription factor ATF-7; Plays important functions in early cell signaling. Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AG][AG]-3'), a sequence present in many viral and cellular promoters. (494 aa)
CREB3L3cAMP responsive element binding protein 3 like 3. (415 aa)
TRAF4TNF receptor-associated factor. (422 aa)
NFE2L1Nuclear factor, erythroid 2 like 1. (772 aa)
RPS6KA4Ribosomal protein S6 kinase. (755 aa)
RPS6KA5Ribosomal protein S6 kinase. (802 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
DUSP10Dual specificity phosphatase 10. (488 aa)
Your Current Organism:
Colobus angolensis
NCBI taxonomy Id: 336983
Other names: C. angolensis palliatus, Colobus angolensis palliatus
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