(26 nodes) Mixed, incl. Preribosome, large subunit precursor, and 60S ribosome subunit biogenesis protein NIP7, pre-PUA domain network (Colobus angolensis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	DDX55	RNA helicase. (600 aa)
	LOC105502228	Ribosome assembly factor mrt4; Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes. (225 aa)
	BRIX1	Biogenesis of ribosomes BRX1. (358 aa)
	EBNA1BP2	EBNA1 binding protein 2. (310 aa)
	ENSCANP00000010978	Uncharacterized protein; Belongs to the DEAD box helicase family. (619 aa)
	RSL1D1	Ribosomal L1 domain containing 1. (487 aa)
	RSL24D1	Ribosomal L24 domain containing 1. (163 aa)
	NIP7	60S ribosome subunit biogenesis protein NIP7 homolog; Required for proper 34S pre-rRNA processing and 60S ribosome subunit assembly; Belongs to the NIP7 family. (180 aa)
	MAK16	Protein MAK16 homolog; Belongs to the MAK16 family. (300 aa)
	NOC3L	Nucleolar complex protein 3 homolog. (801 aa)
	NSUN6	NOP2/Sun RNA methyltransferase 6; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (469 aa)
	NOC2L	NOC2 like nucleolar associated transcriptional repressor. (679 aa)
	GNL3L	G protein nucleolar 3 like. (583 aa)
	WDR12	Ribosome biogenesis protein WDR12; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (383 aa)
	NIFK	Nucleolar protein interacting with the FHA domain of MKI67. (293 aa)
	BOP1	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (746 aa)
	NOP2	SAM_MT_RSMB_NOP domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (839 aa)
	ENSCANP00000031610	Uncharacterized protein. (137 aa)
	GNL3	G protein nucleolar 3. (537 aa)
	PES1	Pescadillo homolog; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome; Belongs to the pescadillo family. (586 aa)
	LOC105511668	WD_REPEATS_REGION domain-containing protein. (370 aa)
	LOC105501734	UPF0113_N domain-containing protein. (125 aa)
	RRP1	Ribosomal RNA processing 1. (423 aa)
	RPF1	Ribosome production factor 1 homolog. (349 aa)
	FTSJ3	pre-rRNA processing protein FTSJ3; Probable methyltransferase involved in the processing of the 34S pre-rRNA to 18S rRNA and in 40S ribosomal subunit formation. Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. SPB1 subfamily. (843 aa)
	WDR74	WD repeat domain 74. (385 aa)

Your Current Organism:

Colobus angolensis

NCBI taxonomy Id: 336983
Other names: C. angolensis palliatus, Colobus angolensis palliatus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BOP1	BRIX1	ENSCANP00000030156	ENSCANP00000006886	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Biogenesis of ribosomes BRX1.	0.997
BOP1	DDX55	ENSCANP00000030156	ENSCANP00000000082	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	RNA helicase.	0.983
BOP1	EBNA1BP2	ENSCANP00000030156	ENSCANP00000010099	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	EBNA1 binding protein 2.	0.997
BOP1	ENSCANP00000010978	ENSCANP00000030156	ENSCANP00000010978	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Uncharacterized protein; Belongs to the DEAD box helicase family.	0.977
BOP1	ENSCANP00000031610	ENSCANP00000030156	ENSCANP00000031610	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Uncharacterized protein.	0.965
BOP1	FTSJ3	ENSCANP00000030156	ENSCANP00000038492	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	pre-rRNA processing protein FTSJ3; Probable methyltransferase involved in the processing of the 34S pre-rRNA to 18S rRNA and in 40S ribosomal subunit formation. Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. SPB1 subfamily.	0.992
BOP1	GNL3	ENSCANP00000030156	ENSCANP00000032599	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	G protein nucleolar 3.	0.991
BOP1	GNL3L	ENSCANP00000030156	ENSCANP00000023812	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	G protein nucleolar 3 like.	0.991
BOP1	LOC105501734	ENSCANP00000030156	ENSCANP00000035479	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	UPF0113_N domain-containing protein.	0.973
BOP1	LOC105502228	ENSCANP00000030156	ENSCANP00000001468	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Ribosome assembly factor mrt4; Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes.	0.977
BOP1	LOC105511668	ENSCANP00000030156	ENSCANP00000034489	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	WD_REPEATS_REGION domain-containing protein.	0.996
BOP1	MAK16	ENSCANP00000030156	ENSCANP00000017538	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Protein MAK16 homolog; Belongs to the MAK16 family.	0.978
BOP1	NIFK	ENSCANP00000030156	ENSCANP00000025594	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Nucleolar protein interacting with the FHA domain of MKI67.	0.991
BOP1	NIP7	ENSCANP00000030156	ENSCANP00000012831	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	60S ribosome subunit biogenesis protein NIP7 homolog; Required for proper 34S pre-rRNA processing and 60S ribosome subunit assembly; Belongs to the NIP7 family.	0.973
BOP1	NOC2L	ENSCANP00000030156	ENSCANP00000021682	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	NOC2 like nucleolar associated transcriptional repressor.	0.996
BOP1	NOC3L	ENSCANP00000030156	ENSCANP00000018175	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Nucleolar complex protein 3 homolog.	0.992
BOP1	NOP2	ENSCANP00000030156	ENSCANP00000030408	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	SAM_MT_RSMB_NOP domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.	0.988
BOP1	NSUN6	ENSCANP00000030156	ENSCANP00000020962	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	NOP2/Sun RNA methyltransferase 6; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.	0.988
BOP1	PES1	ENSCANP00000030156	ENSCANP00000032660	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Pescadillo homolog; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome; Belongs to the pescadillo family.	0.999
BOP1	RPF1	ENSCANP00000030156	ENSCANP00000037902	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Ribosome production factor 1 homolog.	0.985