(5 nodes) Mixed, incl. Transmembrane protein 178A/B, and EXPERA domain network (Colobus angolensis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	TMEM88	Uncharacterized protein. (173 aa)
	PGRMC1	Progesterone receptor membrane component 1; Belongs to the cytochrome b5 family. (195 aa)
	TMEM97	Transmembrane protein 97; Intracellular orphan receptor that binds numerous drugs and which is highly expressed in various proliferating cells. Corresponds to the sigma-2 receptor, which is thought to play important role in regulating cell survival, morphology and differentiation. May play a role as a regulator of cellular cholesterol homeostasis. May function as sterol isomerase. May alter the activity of some cytochrome P450 proteins. (176 aa)
	TMEM178A	Transmembrane protein 178A. (163 aa)
	TMEM94	Transmembrane protein 94. (1366 aa)

Your Current Organism:

Colobus angolensis

NCBI taxonomy Id: 336983
Other names: C. angolensis palliatus, Colobus angolensis palliatus

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
PGRMC1	TMEM97	ENSCANP00000010332	ENSCANP00000011129	Progesterone receptor membrane component 1; Belongs to the cytochrome b5 family.	Transmembrane protein 97; Intracellular orphan receptor that binds numerous drugs and which is highly expressed in various proliferating cells. Corresponds to the sigma-2 receptor, which is thought to play important role in regulating cell survival, morphology and differentiation. May play a role as a regulator of cellular cholesterol homeostasis. May function as sterol isomerase. May alter the activity of some cytochrome P450 proteins.	0.662
TMEM178A	TMEM88	ENSCANP00000024518	ENSCANP00000000730	Transmembrane protein 178A.	Uncharacterized protein.	0.540
TMEM178A	TMEM94	ENSCANP00000024518	ENSCANP00000039504	Transmembrane protein 178A.	Transmembrane protein 94.	0.600
TMEM178A	TMEM97	ENSCANP00000024518	ENSCANP00000011129	Transmembrane protein 178A.	Transmembrane protein 97; Intracellular orphan receptor that binds numerous drugs and which is highly expressed in various proliferating cells. Corresponds to the sigma-2 receptor, which is thought to play important role in regulating cell survival, morphology and differentiation. May play a role as a regulator of cellular cholesterol homeostasis. May function as sterol isomerase. May alter the activity of some cytochrome P450 proteins.	0.550
TMEM88	TMEM178A	ENSCANP00000000730	ENSCANP00000024518	Uncharacterized protein.	Transmembrane protein 178A.	0.540
TMEM88	TMEM94	ENSCANP00000000730	ENSCANP00000039504	Uncharacterized protein.	Transmembrane protein 94.	0.546
TMEM88	TMEM97	ENSCANP00000000730	ENSCANP00000011129	Uncharacterized protein.	Transmembrane protein 97; Intracellular orphan receptor that binds numerous drugs and which is highly expressed in various proliferating cells. Corresponds to the sigma-2 receptor, which is thought to play important role in regulating cell survival, morphology and differentiation. May play a role as a regulator of cellular cholesterol homeostasis. May function as sterol isomerase. May alter the activity of some cytochrome P450 proteins.	0.400
TMEM94	TMEM178A	ENSCANP00000039504	ENSCANP00000024518	Transmembrane protein 94.	Transmembrane protein 178A.	0.600
TMEM94	TMEM88	ENSCANP00000039504	ENSCANP00000000730	Transmembrane protein 94.	Uncharacterized protein.	0.546
TMEM94	TMEM97	ENSCANP00000039504	ENSCANP00000011129	Transmembrane protein 94.	Transmembrane protein 97; Intracellular orphan receptor that binds numerous drugs and which is highly expressed in various proliferating cells. Corresponds to the sigma-2 receptor, which is thought to play important role in regulating cell survival, morphology and differentiation. May play a role as a regulator of cellular cholesterol homeostasis. May function as sterol isomerase. May alter the activity of some cytochrome P450 proteins.	0.559
TMEM97	PGRMC1	ENSCANP00000011129	ENSCANP00000010332	Transmembrane protein 97; Intracellular orphan receptor that binds numerous drugs and which is highly expressed in various proliferating cells. Corresponds to the sigma-2 receptor, which is thought to play important role in regulating cell survival, morphology and differentiation. May play a role as a regulator of cellular cholesterol homeostasis. May function as sterol isomerase. May alter the activity of some cytochrome P450 proteins.	Progesterone receptor membrane component 1; Belongs to the cytochrome b5 family.	0.662
TMEM97	TMEM178A	ENSCANP00000011129	ENSCANP00000024518	Transmembrane protein 97; Intracellular orphan receptor that binds numerous drugs and which is highly expressed in various proliferating cells. Corresponds to the sigma-2 receptor, which is thought to play important role in regulating cell survival, morphology and differentiation. May play a role as a regulator of cellular cholesterol homeostasis. May function as sterol isomerase. May alter the activity of some cytochrome P450 proteins.	Transmembrane protein 178A.	0.550
TMEM97	TMEM88	ENSCANP00000011129	ENSCANP00000000730	Transmembrane protein 97; Intracellular orphan receptor that binds numerous drugs and which is highly expressed in various proliferating cells. Corresponds to the sigma-2 receptor, which is thought to play important role in regulating cell survival, morphology and differentiation. May play a role as a regulator of cellular cholesterol homeostasis. May function as sterol isomerase. May alter the activity of some cytochrome P450 proteins.	Uncharacterized protein.	0.400
TMEM97	TMEM94	ENSCANP00000011129	ENSCANP00000039504	Transmembrane protein 97; Intracellular orphan receptor that binds numerous drugs and which is highly expressed in various proliferating cells. Corresponds to the sigma-2 receptor, which is thought to play important role in regulating cell survival, morphology and differentiation. May play a role as a regulator of cellular cholesterol homeostasis. May function as sterol isomerase. May alter the activity of some cytochrome P450 proteins.	Transmembrane protein 94.	0.559