STRINGSTRING
SNRPD2 SNRPD2 SF3B5 SF3B5 DDX17 DDX17 PRPF4 PRPF4 SNRPF SNRPF LOC105517174 LOC105517174 SNRPG SNRPG TCERG1 TCERG1 PQBP1 PQBP1 DDX46 DDX46 LSM3-2 LSM3-2 SNRPD2-2 SNRPD2-2 LSM3-3 LSM3-3 LSM1 LSM1 SNRPB SNRPB SF3A2 SF3A2 EFTUD2 EFTUD2 ENSCANP00000008832 ENSCANP00000008832 SNRPC SNRPC SRRM1 SRRM1 ENSCANP00000010049 ENSCANP00000010049 RBM41 RBM41 SF3B1 SF3B1 PRPF31 PRPF31 SF3B6 SF3B6 WBP11 WBP11 TXNL4B TXNL4B SNRPD3 SNRPD3 PHF5A PHF5A ENSCANP00000017388 ENSCANP00000017388 SNRPA1 SNRPA1 ENSCANP00000017579 ENSCANP00000017579 ENSCANP00000017774 ENSCANP00000017774 PRPF38A PRPF38A DHX9 DHX9 UBL5 UBL5 SF3A1 SF3A1 SNRNP27 SNRNP27 LRMDA LRMDA LSM3 LSM3 ENSCANP00000021234 ENSCANP00000021234 WBP4 WBP4 TMIGD2 TMIGD2 SNRNP200 SNRNP200 USP39 USP39 ENSCANP00000023614 ENSCANP00000023614 LSM7 LSM7 ENSCANP00000024333 ENSCANP00000024333 SF3B4 SF3B4 SNRPD2-3 SNRPD2-3 SNRPE SNRPE SNRPB2 SNRPB2 SNRNP70 SNRNP70 LOC105526986 LOC105526986 PRPF3 PRPF3 MFAP1 MFAP1 ENSCANP00000027926 ENSCANP00000027926 LSM3-4 LSM3-4 PRPF6 PRPF6 DAW1 DAW1 SMU1 SMU1 ENSCANP00000029739 ENSCANP00000029739 LOC105525000 LOC105525000 DDX5 DDX5 SNRPA SNRPA CD2BP2 CD2BP2 ZMAT2 ZMAT2 LSM2 LSM2 TXNL4A TXNL4A SF3B2 SF3B2 LSM5 LSM5 DDX23 DDX23 LSM8 LSM8 ENSCANP00000034388 ENSCANP00000034388 ENSCANP00000034448 ENSCANP00000034448 SNRPN SNRPN LSM6 LSM6 TGS1 TGS1 SF3A3 SF3A3 ENSCANP00000037401 ENSCANP00000037401 LOC105503616 LOC105503616 SPACA6 SPACA6 PPIH PPIH SF3B3 SF3B3 PRPF8 PRPF8 SART1 SART1 SNRNP40 SNRNP40 LSM4 LSM4 ENSCANP00000040051 ENSCANP00000040051
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SNRPD2Small nuclear ribonucleoprotein Sm D2; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. (54 aa)
SF3B5Splicing factor 3B subunit 5; Belongs to the SF3B5 family. (86 aa)
DDX17DEAD-box helicase 17; Belongs to the DEAD box helicase family. (735 aa)
PRPF4Pre-mRNA processing factor 4. (539 aa)
SNRPFSm domain-containing protein. (127 aa)
LOC105517174Sm domain-containing protein. (80 aa)
SNRPGSmall nuclear ribonucleoprotein G; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. (96 aa)
TCERG1Transcription elongation regulator 1. (1094 aa)
PQBP1Polyglutamine binding protein 1. (265 aa)
DDX46DEAD-box helicase 46; Belongs to the DEAD box helicase family. (617 aa)
LSM3-2U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (87 aa)
SNRPD2-2Small nuclear ribonucleoprotein Sm D2; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. (59 aa)
LSM3-3U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (102 aa)
LSM1U6 snRNA-associated Sm-like protein LSm1; Plays a role in the degradation of histone mRNAs, the only eukaryotic mRNAs that are not polyadenylated. Probably also part of an LSm subunits-containing complex involved in the general process of mRNA degradation. (133 aa)
SNRPBSmall nuclear ribonucleoprotein-associated protein. (240 aa)
SF3A2Splicing factor 3a subunit 2. (464 aa)
EFTUD2Elongation factor Tu GTP binding domain containing 2. (972 aa)
ENSCANP00000008832Small nuclear ribonucleoprotein G; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. (63 aa)
SNRPCU1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region. Belongs to the U1 [...] (171 aa)
SRRM1Serine and arginine repetitive matrix 1. (913 aa)
ENSCANP00000010049Small nuclear ribonucleoprotein E; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. May indirectly play a role in hair development. (70 aa)
RBM41RNA binding motif protein 41. (409 aa)
SF3B1Splicing factor 3b subunit 1. (1307 aa)
PRPF31Pre-mRNA processing factor 31. (499 aa)
SF3B6Splicing factor 3b subunit 6. (125 aa)
WBP11WW domain binding protein 11. (641 aa)
TXNL4BThioredoxin-like protein; Plays role in pre-mRNA splicing. Belongs to the DIM1 family. (149 aa)
SNRPD3Small nuclear ribonucleoprotein Sm D3; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone pre-mRNA 3'-end processing. (126 aa)
PHF5APHD finger protein 5A. (110 aa)
ENSCANP00000017388RRM domain-containing protein. (85 aa)
SNRPA1Small nuclear ribonucleoprotein polypeptide A. (255 aa)
ENSCANP00000017579SEC63 domain-containing protein. (264 aa)
ENSCANP00000017774Small nuclear ribonucleoprotein G; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. (63 aa)
PRPF38APre-mRNA processing factor 38A. (299 aa)
DHX9DExH-box helicase 9. (1275 aa)
UBL5Ubiquitin like 5. (73 aa)
SF3A1Splicing factor 3a subunit 1. (793 aa)
SNRNP27SNRNP27 domain-containing protein. (158 aa)
LRMDALeucine rich melanocyte differentiation associated. (226 aa)
LSM3U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (102 aa)
ENSCANP00000021234Helicase ATP-binding domain-containing protein. (471 aa)
WBP4WW domain binding protein 4. (376 aa)
TMIGD2Transmembrane and immunoglobulin domain containing 2. (276 aa)
SNRNP200Small nuclear ribonucleoprotein U5 subunit 200. (2055 aa)
USP39Ubiquitin specific peptidase 39. (471 aa)
ENSCANP00000023614Sm domain-containing protein. (71 aa)
LSM7LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated. (103 aa)
ENSCANP00000024333Uncharacterized protein. (424 aa)
SF3B4Splicing factor 3b subunit 4. (424 aa)
SNRPD2-3Small nuclear ribonucleoprotein Sm D2; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. (101 aa)
SNRPESmall nuclear ribonucleoprotein E; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. May indirectly play a role in hair development. (92 aa)
SNRPB2Small nuclear ribonucleoprotein polypeptide B2. (225 aa)
SNRNP70Small nuclear ribonucleoprotein U1 subunit 70. (438 aa)
LOC105526986U1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region. Belongs to the U1 [...] (152 aa)
PRPF3Pre-mRNA processing factor 3. (681 aa)
MFAP1Microfibril associated protein 1. (439 aa)
ENSCANP00000027926Uncharacterized protein. (61 aa)
LSM3-4U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (102 aa)
PRPF6Pre-mRNA processing factor 6. (941 aa)
DAW1Dynein assembly factor with WD repeats 1. (400 aa)
SMU1SMU1 DNA replication regulator and spliceosomal factor. (499 aa)
ENSCANP00000029739Small nuclear ribonucleoprotein E; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. May indirectly play a role in hair development. (87 aa)
LOC105525000Small nuclear ribonucleoprotein Sm D2; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. (118 aa)
DDX5DEAD-box helicase 5; Belongs to the DEAD box helicase family. (614 aa)
SNRPASmall nuclear ribonucleoprotein polypeptide A. (282 aa)
CD2BP2CD2 cytoplasmic tail binding protein 2. (341 aa)
ZMAT2Zinc finger matrin-type 2. (199 aa)
LSM2U6 snRNA-associated Sm-like protein LSm2; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (95 aa)
TXNL4AThioredoxin-like protein; Plays role in pre-mRNA splicing. Belongs to the DIM1 family. (142 aa)
SF3B2Splicing factor 3b subunit 2. (895 aa)
LSM5U6 snRNA-associated Sm-like protein LSm5; Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA. (91 aa)
DDX23DEAD-box helicase 23; Belongs to the DEAD box helicase family. (713 aa)
LSM8U6 snRNA-associated Sm-like protein LSm8; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA. (96 aa)
ENSCANP00000034388Sm domain-containing protein. (30 aa)
ENSCANP00000034448RED_C domain-containing protein. (146 aa)
SNRPNSmall nuclear ribonucleoprotein-associated protein. (244 aa)
LSM6LSM6 homolog, U6 small nuclear RNA and mRNA degradation associated. (80 aa)
TGS1Trimethylguanosine synthase 1. (855 aa)
SF3A3Splicing factor 3a subunit 3. (504 aa)
ENSCANP00000037401Uncharacterized protein. (53 aa)
LOC105503616Uncharacterized protein; Belongs to the DEAD box helicase family. (746 aa)
SPACA6Sperm acrosome associated 6. (324 aa)
PPIHPeptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (177 aa)
SF3B3Splicing factor 3b subunit 3. (1195 aa)
PRPF8Pre-mRNA processing factor 8. (2335 aa)
SART1Spliceosome associated factor 1, recruiter of U4/U6.U5 tri-snRNP. (752 aa)
SNRNP40Small nuclear ribonucleoprotein U5 subunit 40. (357 aa)
LSM4U6 snRNA-associated Sm-like protein LSm4; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (139 aa)
ENSCANP00000040051Sm domain-containing protein. (54 aa)
Your Current Organism:
Colobus angolensis
NCBI taxonomy Id: 336983
Other names: C. angolensis palliatus, Colobus angolensis palliatus
Server load: low (14%) [HD]