Proteins whose genes are observed to be correlated in expression, across a large number of experiments.
STRING allows inspection of the interaction evidence for any given network. Choose any of the viewers above (disabled if not applicable in your network).
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes: query proteins and first shell of interactors
white nodes: second shell of interactors
Node Content
empty nodes: proteins of unknown 3D structure
filled nodes: a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RYBP
RING1 and YY1 binding protein. (230 aa)
RING1
Ring finger protein 1. (406 aa)
PCGF5
Polycomb group ring finger 5. (256 aa)
RNF2
Ring finger protein 2. (336 aa)
YAF2
YY1 associated factor 2. (204 aa)
Your Current Organism:
Colobus angolensis
NCBI taxonomy Id: 336983 Other names: C. angolensis palliatus, Colobus angolensis palliatus