STRINGSTRING
ERN1 ERN1 CRK CRK HPR HPR PAX2 PAX2 MAPK3 MAPK3 STK24 STK24 MAP1LC3A MAP1LC3A ENSCANP00000015289 ENSCANP00000015289 IMPACT IMPACT RNF112 RNF112 NOS3 NOS3 AKT1 AKT1 RESP18 RESP18 NFE2L2 NFE2L2 SOD1 SOD1 LOC105517352 LOC105517352 IL18BP IL18BP STK25 STK25 LOC105512773 LOC105512773 TRPA1 TRPA1 LOC105517597 LOC105517597 PRKAA1 PRKAA1 PDCD10 PDCD10 PTK2B PTK2B MAPK9 MAPK9 FANCC FANCC ZNF580 ZNF580 PXN PXN FN1 FN1 PLK3 PLK3 PDGFRB PDGFRB PPP1R15B PPP1R15B RIPK1 RIPK1 SIRT1 SIRT1 ERCC6L2 ERCC6L2 CAT CAT MAPK13 MAPK13 MMP9 MMP9 SETX SETX ABL1 ABL1 RELA RELA NCF1 NCF1 NET1 NET1 SOD2 SOD2 SDC1 SDC1 LOC105524062 LOC105524062 NUDT15 NUDT15 BNIP3 BNIP3 KDM6B KDM6B ANKZF1 ANKZF1 ROMO1 ROMO1 ENSCANP00000005856 ENSCANP00000005856 MAPK7 MAPK7 UCP3 UCP3 CHUK CHUK ENSCANP00000005241 ENSCANP00000005241 BAD BAD BCL2 BCL2 CAMKK2 CAMKK2 PRKCD PRKCD SOD3 SOD3 TRPM2 TRPM2 APOD APOD RBX1 RBX1 KCNA5 KCNA5 UBE3A UBE3A ADAM9 ADAM9 AGAP3 AGAP3 ENSCANP00000002057 ENSCANP00000002057 ENSCANP00000001808 ENSCANP00000001808 PKD2 PKD2 CRYGD CRYGD RHOB RHOB HYAL1 HYAL1 PCGF2 PCGF2 EDN1 EDN1 PRDX1 PRDX1 ENSCANP00000000401 ENSCANP00000000401 PLEKHA1 PLEKHA1 TACR1 TACR1 CYP1B1 CYP1B1 SIGMAR1 SIGMAR1 SRC SRC LOC105523716 LOC105523716 FOS FOS MAPK10 MAPK10 FXN FXN FKBP1B FKBP1B EGFR EGFR FYN FYN ENSCANP00000017887 ENSCANP00000017887 EZH2 EZH2 JUN JUN ERCC6 ERCC6 ECT2 ECT2 PJVK PJVK RIPK3 RIPK3 OSER1 OSER1 ENSCANP00000031429 ENSCANP00000031429 ZNF277 ZNF277 MPV17 MPV17 NME8 NME8 BTK BTK SLC8A1 SLC8A1 HIF1A HIF1A PPARGC1B PPARGC1B HDAC6 HDAC6 PPP2CB PPP2CB AXL AXL ATP7A ATP7A TNFAIP3 TNFAIP3 STAT1 STAT1 ARG1 ARG1 MAPK1 MAPK1 ENSCANP00000026065 ENSCANP00000026065 RPS3 RPS3 MAP3K5 MAP3K5 GPX1 GPX1 FER FER HDAC2 HDAC2 SPHK1 SPHK1 MPO MPO FABP1 FABP1 STK26 STK26 HYAL2 HYAL2 COL1A1 COL1A1 ENSCANP00000022906 ENSCANP00000022906 MUC5AC MUC5AC LOC105506994 LOC105506994 BAK1 BAK1 LOC105521701 LOC105521701 ADPRHL2 ADPRHL2 FOSL1 FOSL1 ENSCANP00000034378 ENSCANP00000034378 SMPD3 SMPD3 LOC105501966 LOC105501966 AIFM1 AIFM1 UCP1 UCP1 LOC105501854 LOC105501854 S100A7L2 S100A7L2 GLRX2 GLRX2 PTPRK PTPRK LOC105521702 LOC105521702 ENSCANP00000037159 ENSCANP00000037159 MT3 MT3 AMBP AMBP PARK7 PARK7 PDK2 PDK2 PRDX5 PRDX5 HSF1 HSF1 IL6 IL6 PPIF PPIF LOC105525831 LOC105525831 LOC105503257 LOC105503257 AREG AREG COA8 COA8 ENSCANP00000020723 ENSCANP00000020723 MAPK8 MAPK8 PTPRN PTPRN AKR1C3 AKR1C3 STAT6 STAT6 CCS CCS
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ERN1Endoplasmic reticulum to nucleus signaling 1. (979 aa)
CRKCRK proto-oncogene, adaptor protein. (304 aa)
HPRHaptoglobin-related protein; Belongs to the peptidase S1 family. (346 aa)
PAX2Paired box 2. (388 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (380 aa)
STK24Serine/threonine kinase 24. (443 aa)
MAP1LC3AMicrotubule associated protein 1 light chain 3 alpha. (125 aa)
ENSCANP00000015289Uncharacterized protein. (58 aa)
IMPACTImpact RWD domain protein. (320 aa)
RNF112Ring finger protein 112. (639 aa)
NOS3Nitric oxide synthase; Produces nitric oxide (NO). (1205 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (488 aa)
RESP18Regulated endocrine specific protein 18. (228 aa)
NFE2L2Nuclear factor, erythroid 2 like 2. (601 aa)
SOD1Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family. (154 aa)
LOC105517352Uncharacterized protein; Belongs to the beta/gamma-crystallin family. (174 aa)
IL18BPInterleukin 18 binding protein. (208 aa)
STK25Serine/threonine kinase 25. (416 aa)
LOC105512773Uncharacterized protein. (507 aa)
TRPA1Transient receptor potential cation channel subfamily A member 1; Belongs to the transient receptor (TC 1.A.4) family. (1116 aa)
LOC105517597DJ-1_PfpI domain-containing protein. (201 aa)
PRKAA1Non-specific serine/threonine protein kinase. (574 aa)
PDCD10Uncharacterized protein. (212 aa)
PTK2BProtein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1009 aa)
MAPK9Mitogen-activated protein kinase. (399 aa)
FANCCFanconi anemia group C protein homolog; DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. Upon IFNG induction, may facilitate STAT1 activation by recruiting STAT1 to IFNGR1. (558 aa)
ZNF580Zinc finger protein 580. (90 aa)
PXNPaxillin. (1076 aa)
FN1Fibronectin 1. (2450 aa)
PLK3Serine/threonine-protein kinase PLK. (636 aa)
PDGFRBPlatelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1106 aa)
PPP1R15BProtein phosphatase 1 regulatory subunit 15B. (499 aa)
RIPK1Receptor interacting serine/threonine kinase 1. (625 aa)
SIRT1Sirtuin 1. (600 aa)
ERCC6L2ERCC excision repair 6 like 2. (713 aa)
CATCatalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. (527 aa)
MAPK13Mitogen-activated protein kinase. (491 aa)
MMP9Matrix metallopeptidase 9. (707 aa)
SETXSenataxin. (2666 aa)
ABL1Tyrosine-protein kinase. (1149 aa)
RELARELA proto-oncogene, NF-kB subunit. (548 aa)
NCF1Neutrophil cytosolic factor 1. (390 aa)
NET1Neuroepithelial cell transforming 1. (595 aa)
SOD2Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (236 aa)
SDC1Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (288 aa)
LOC105524062Pyr_redox_2 domain-containing protein. (108 aa)
NUDT15Nudix hydrolase domain-containing protein. (164 aa)
BNIP3BCL2 interacting protein 3. (185 aa)
KDM6BLysine demethylase 6B. (1689 aa)
ANKZF1Ankyrin repeat and zinc finger peptidyl tRNA hydrolase 1. (727 aa)
ROMO1Reactive oxygen species modulator 1. (79 aa)
ENSCANP00000005856Protein kinase domain-containing protein. (392 aa)
MAPK7Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (814 aa)
UCP3Uncoupling protein 3; Belongs to the mitochondrial carrier (TC 2.A.29) family. (312 aa)
CHUKComponent of inhibitor of nuclear factor kappa B kinase complex. (745 aa)
ENSCANP00000005241Uncharacterized protein. (80 aa)
BADBCL2 associated agonist of cell death. (167 aa)
BCL2BCL2 apoptosis regulator. (239 aa)
CAMKK2Calcium/calmodulin dependent protein kinase kinase 2. (576 aa)
PRKCDProtein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (676 aa)
SOD3Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family. (240 aa)
TRPM2Transient receptor potential cation channel subfamily M member 2. (1343 aa)
APODApolipoprotein D. (175 aa)
RBX1Ring-box 1. (108 aa)
KCNA5Potassium voltage-gated channel subfamily A member 5; Belongs to the potassium channel family. (605 aa)
UBE3AUbiquitin-protein ligase E3A; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates. (875 aa)
ADAM9ADAM metallopeptidase domain 9. (819 aa)
AGAP3ArfGAP with GTPase domain, ankyrin repeat and PH domain 3. (899 aa)
ENSCANP00000002057Uncharacterized protein. (147 aa)
ENSCANP00000001808Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family. (144 aa)
PKD2Polycystin 2, transient receptor potential cation channel. (780 aa)
CRYGDCrystallin gamma D; Belongs to the beta/gamma-crystallin family. (174 aa)
RHOBRas homolog family member B. (196 aa)
HYAL1Hyaluronidase. (450 aa)
PCGF2Polycomb group ring finger 2. (344 aa)
EDN1Endothelin 1. (211 aa)
PRDX11-cysPrx_C domain-containing protein. (97 aa)
ENSCANP00000000401Redoxin domain-containing protein. (143 aa)
PLEKHA1Pleckstrin homology domain containing A1. (404 aa)
TACR1Tachykinin receptor 1; Belongs to the G-protein coupled receptor 1 family. (407 aa)
CYP1B1Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family. (543 aa)
SIGMAR1Sigma non-opioid intracellular receptor 1. (223 aa)
SRCTyrosine-protein kinase. (458 aa)
LOC105523716Thioredoxin reductase 2. (398 aa)
FOSFos proto-oncogene, AP-1 transcription factor subunit. (380 aa)
MAPK10Mitogen-activated protein kinase. (550 aa)
FXNFrataxin. (135 aa)
FKBP1BPeptidylprolyl isomerase. (108 aa)
EGFRReceptor protein-tyrosine kinase. (1188 aa)
FYNTyrosine-protein kinase. (537 aa)
ENSCANP00000017887Uncharacterized protein. (146 aa)
EZH2Enhancer of zeste 2 polycomb repressive complex 2 subunit. (746 aa)
JUNJun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (246 aa)
ERCC6ERCC excision repair 6, chromatin remodeling factor. (1494 aa)
ECT2Epithelial cell transforming 2. (904 aa)
PJVKPejvakin. (352 aa)
RIPK3Receptor interacting serine/threonine kinase 3. (518 aa)
OSER1Oxidative stress responsive serine rich 1. (292 aa)
ENSCANP00000031429DJ-1_PfpI domain-containing protein. (124 aa)
ZNF277Zinc finger protein 277. (456 aa)
MPV17Mitochondrial inner membrane protein MPV17; Belongs to the peroxisomal membrane protein PXMP2/4 family. (191 aa)
NME8NME/NM23 family member 8. (588 aa)
BTKTyrosine-protein kinase. (692 aa)
SLC8A1Solute carrier family 8 member A1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (973 aa)
HIF1AHypoxia inducible factor 1 subunit alpha. (827 aa)
PPARGC1BPPARG coactivator 1 beta. (1025 aa)
HDAC6Histone deacetylase 6. (1217 aa)
PPP2CBSerine/threonine-protein phosphatase. (275 aa)
AXLAXL receptor tyrosine kinase. (894 aa)
ATP7AATPase copper transporting alpha. (1500 aa)
TNFAIP3TNF alpha induced protein 3. (790 aa)
STAT1Signal transducer and activator of transcription. (765 aa)
ARG1Arginase. (322 aa)
MAPK1Mitogen-activated protein kinase. (343 aa)
ENSCANP00000026065Uncharacterized protein. (76 aa)
RPS3Ribosomal protein S3; Belongs to the universal ribosomal protein uS3 family. (259 aa)
MAP3K5Mitogen-activated protein kinase kinase kinase 5. (1364 aa)
GPX1Glutathione peroxidase; Belongs to the glutathione peroxidase family. (200 aa)
FERTyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (822 aa)
HDAC2Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (488 aa)
SPHK1Sphingosine kinase 1. (448 aa)
MPOMyeloperoxidase. (745 aa)
FABP1Fatty acid binding protein 1. (127 aa)
STK26Serine/threonine kinase 26. (438 aa)
HYAL2Hyaluronidase. (473 aa)
COL1A1Collagen type I alpha 1 chain. (1464 aa)
ENSCANP00000022906Thioredoxin domain-containing protein. (173 aa)
MUC5ACMucin 5AC, oligomeric mucus/gel-forming. (4052 aa)
LOC105506994Nudix hydrolase domain-containing protein. (148 aa)
BAK1BCL2 antagonist/killer 1. (211 aa)
LOC105521701Aldo-keto reductase family 1 member C1. (323 aa)
ADPRHL2ADP-ribosylhydrolase like 2. (363 aa)
FOSL1FOS like 1, AP-1 transcription factor subunit. (271 aa)
ENSCANP00000034378Uncharacterized protein. (198 aa)
SMPD3Sphingomyelin phosphodiesterase 3. (655 aa)
LOC105501966Protein S100; Belongs to the S-100 family. (101 aa)
AIFM1Apoptosis inducing factor mitochondria associated 1. (565 aa)
UCP1Uncoupling protein 1; Belongs to the mitochondrial carrier (TC 2.A.29) family. (307 aa)
LOC105501854Ribosomal_S3_C domain-containing protein; Belongs to the universal ribosomal protein uS3 family. (252 aa)
S100A7L2S100 calcium binding protein A7 like 2. (113 aa)
GLRX2Glutaredoxin 2. (167 aa)
PTPRKProtein tyrosine phosphatase receptor type K. (1421 aa)
LOC105521702Aldo_ket_red domain-containing protein. (323 aa)
ENSCANP00000037159Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (113 aa)
MT3Metallothionein 3; Belongs to the metallothionein superfamily. Type 1 family. (113 aa)
AMBPAlpha-1-microglobulin/bikunin precursor. (352 aa)
PARK7Parkinsonism associated deglycase. (189 aa)
PDK2Protein-serine/threonine kinase. (407 aa)
PRDX5Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily. (181 aa)
HSF1Heat shock transcription factor 1. (521 aa)
IL6Interleukin 6. (214 aa)
PPIFPeptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (159 aa)
LOC105525831Peptidase S1 domain-containing protein. (433 aa)
LOC105503257Uncharacterized protein. (194 aa)
AREGAmphiregulin. (275 aa)
COA8Cytochrome c oxidase assembly factor 8. (206 aa)
ENSCANP00000020723Uncharacterized protein. (181 aa)
MAPK8Mitogen-activated protein kinase. (427 aa)
PTPRNProtein tyrosine phosphatase receptor type N. (979 aa)
AKR1C3Aldo-keto reductase family 1 member C3. (323 aa)
STAT6Signal transducer and activator of transcription. (847 aa)
CCSCopper chaperone for superoxide dismutase. (274 aa)
Your Current Organism:
Colobus angolensis
NCBI taxonomy Id: 336983
Other names: C. angolensis palliatus, Colobus angolensis palliatus
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