STRINGSTRING
PRIMPOL PRIMPOL LOC105509448 LOC105509448 SYCP1 SYCP1 CDKN2D CDKN2D RCHY1 RCHY1 MAD2L2 MAD2L2 POLD2 POLD2 USP1 USP1 SIRT1 SIRT1 WRNIP1 WRNIP1 POLDIP2 POLDIP2 RFC3 RFC3 PCNA PCNA HROB HROB DTL DTL SPRTN SPRTN TEX12 TEX12 POLI POLI USP43 USP43 POLD3 POLD3 POLE2 POLE2 POLA1 POLA1 WRN WRN POLH POLH PCLAF PCLAF SPATA22 SPATA22 POLD1 POLD1 POLN POLN POLD4 POLD4 PARP10 PARP10 VCP VCP POLE POLE REV3L REV3L USP10 USP10 ZBTB1 ZBTB1 REV1 REV1 POLK POLK
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PRIMPOLPrimase and DNA directed polymerase. (560 aa)
LOC105509448Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (245 aa)
SYCP1Synaptonemal complex protein 1. (976 aa)
CDKN2DCyclin dependent kinase inhibitor 2D. (166 aa)
RCHY1Ring finger and CHY zinc finger domain containing 1. (261 aa)
MAD2L2Mitotic arrest deficient 2 like 2. (210 aa)
POLD2DNA polymerase delta 2, accessory subunit. (504 aa)
USP1Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (783 aa)
SIRT1Sirtuin 1. (600 aa)
WRNIP1WRN helicase interacting protein 1. (445 aa)
POLDIP2DNA polymerase delta interacting protein 2. (377 aa)
RFC3Replication factor C subunit 3. (356 aa)
PCNAProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)
HROBChromosome 17 open reading frame 53. (645 aa)
DTLDenticleless E3 ubiquitin protein ligase homolog. (702 aa)
SPRTNSprT-like N-terminal domain. (488 aa)
TEX12Testis expressed 12. (123 aa)
POLIDNA polymerase iota. (739 aa)
USP43Ubiquitin specific peptidase 43. (795 aa)
POLD3Uncharacterized protein. (454 aa)
POLE2DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (527 aa)
POLA1DNA polymerase. (1474 aa)
WRNWRN RecQ like helicase. (1431 aa)
POLHDNA polymerase eta. (712 aa)
PCLAFPAF domain-containing protein. (103 aa)
SPATA22Spermatogenesis associated 22. (363 aa)
POLD1DNA polymerase delta 1, catalytic subunit. (1012 aa)
POLNDNA polymerase nu. (900 aa)
POLD4Uncharacterized protein. (107 aa)
PARP10Poly [ADP-ribose] polymerase. (1026 aa)
VCPValosin containing protein; Belongs to the AAA ATPase family. (804 aa)
POLEDNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2267 aa)
REV3LREV3 like, DNA directed polymerase zeta catalytic subunit. (3128 aa)
USP10Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (742 aa)
ZBTB1Zinc finger and BTB domain containing 1. (668 aa)
REV1DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family. (1250 aa)
POLKDNA polymerase kappa. (869 aa)
Your Current Organism:
Colobus angolensis
NCBI taxonomy Id: 336983
Other names: C. angolensis palliatus, Colobus angolensis palliatus
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