STRINGSTRING
PATL1 PATL1 TENT2 TENT2 LSM4 LSM4 LOC105513967 LOC105513967 POLR2D POLR2D CNOT8 CNOT8 EIF4A3 EIF4A3 CNOT7 CNOT7 POLR2G POLR2G RC3H2 RC3H2 BCLAF1 BCLAF1 PNLDC1 PNLDC1 THRAP3 THRAP3 EXOSC10 EXOSC10 ZC3H12A ZC3H12A RBM8A RBM8A EXOSC7 EXOSC7 EDC4 EDC4 SMG9 SMG9 RNPS1 RNPS1 TENT4B TENT4B CNOT1 CNOT1 UPF2 UPF2 EXOSC8 EXOSC8 AGO1 AGO1 EXOSC2 EXOSC2 DXO DXO SKIV2L SKIV2L PABPN1L PABPN1L EXOSC5 EXOSC5 ZFP36L2 ZFP36L2 ENSCANP00000030698 ENSCANP00000030698 PDE12 PDE12 DDX5 DDX5 CNOT11 CNOT11 ENSCANP00000028939 ENSCANP00000028939 CNOT2 CNOT2 XRN1 XRN1 EXOSC9 EXOSC9 DHX34 DHX34 NCBP1 NCBP1 EXOSC3 EXOSC3 ENSCANP00000026116 ENSCANP00000026116 DIS3L2 DIS3L2 NT5C3B NT5C3B TUT4 TUT4 LOC105517234 LOC105517234 ENSCANP00000025588 ENSCANP00000025588 DCP1B DCP1B ETF1 ETF1 TUT7 TUT7 EXOSC4 EXOSC4 GSPT1 GSPT1 MTPAP MTPAP LSM7 LSM7 CSDE1 CSDE1 MAGOH MAGOH SMG1 SMG1 SMG8 SMG8 LOC105518317 LOC105518317 HELZ2 HELZ2 PAN3 PAN3 LOC105512634 LOC105512634 UPF3A UPF3A SWT1 SWT1 ZCCHC7 ZCCHC7 RC3H1 RC3H1 NOCT NOCT DCPS DCPS SMG6 SMG6 ZFP36L1 ZFP36L1 ATM ATM LOC105504658 LOC105504658 CTIF CTIF DCP2 DCP2 ENSCANP00000013556 ENSCANP00000013556 ENSCANP00000013382 ENSCANP00000013382 UPF1 UPF1 MAGOHB MAGOHB TTC37 TTC37 CNOT4 CNOT4 ENSCANP00000011836 ENSCANP00000011836 SMG5 SMG5 UPF3B UPF3B PARN PARN LOC105512457 LOC105512457 EDC3 EDC3 CNOT6L CNOT6L SSB SSB CNOT6 CNOT6 ENSCANP00000007202 ENSCANP00000007202 PABPC1 PABPC1 PELO PELO PYM1 PYM1 ENSCANP00000005866 ENSCANP00000005866 LSM1 LSM1 PAN2 PAN2 SMG7 SMG7 SAMD4B SAMD4B LRRC27 LRRC27 EIF3E EIF3E CNOT3 CNOT3 PATL2 PATL2 ENSCANP00000003829 ENSCANP00000003829 NBAS NBAS ZFP36 ZFP36 MLH1 MLH1 DIS3 DIS3 CASC3 CASC3 NBDY NBDY LOC105502228 LOC105502228 LOC105523459 LOC105523459 MRTO4 MRTO4 DCP1A DCP1A
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PATL1PAT1 homolog 1, processing body mRNA decay factor. (770 aa)
TENT2Terminal nucleotidyltransferase 2. (441 aa)
LSM4U6 snRNA-associated Sm-like protein LSm4; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (139 aa)
LOC105513967eRF1_1 domain-containing protein. (428 aa)
POLR2DRNA polymerase II subunit D. (142 aa)
CNOT8CCR4-NOT transcription complex subunit 8. (292 aa)
EIF4A3Eukaryotic translation initiation factor 4A3. (362 aa)
CNOT7CCR4-NOT transcription complex subunit 7. (285 aa)
POLR2GRNA polymerase II subunit G. (231 aa)
RC3H2Ring finger and CCCH-type domains 2. (1191 aa)
BCLAF1BCL2 associated transcription factor 1. (921 aa)
PNLDC1PARN like, ribonuclease domain containing 1. (520 aa)
THRAP3Thyroid hormone receptor associated protein 3. (955 aa)
EXOSC10Exosome component 10. (884 aa)
ZC3H12AZinc finger CCCH-type containing 12A. (601 aa)
RBM8ARNA-binding protein 8A; Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs. (174 aa)
EXOSC7Exosome component 7. (291 aa)
EDC4Enhancer of mRNA decapping 4. (1398 aa)
SMG9SMG9 nonsense mediated mRNA decay factor. (520 aa)
RNPS1RNA binding protein with serine rich domain 1. (305 aa)
TENT4BTerminal nucleotidyltransferase 4B. (568 aa)
CNOT1CCR4-NOT transcription complex subunit 1. (2382 aa)
UPF2UPF2 regulator of nonsense mediated mRNA decay. (1243 aa)
EXOSC8Exosome component 8. (276 aa)
AGO1Argonaute RISC component 1; Belongs to the argonaute family. (857 aa)
EXOSC2Uncharacterized protein. (293 aa)
DXODecapping exoribonuclease. (396 aa)
SKIV2LSki2 like RNA helicase. (1245 aa)
PABPN1LPoly(A) binding protein nuclear 1 like, cytoplasmic. (276 aa)
EXOSC5Exosome component 5. (235 aa)
ZFP36L2ZFP36 ring finger protein like 2. (299 aa)
ENSCANP00000030698Endo/exonuclease/phosphatase domain-containing protein. (355 aa)
PDE12Phosphodiesterase 12. (609 aa)
DDX5DEAD-box helicase 5; Belongs to the DEAD box helicase family. (614 aa)
CNOT11CCR4-NOT transcription complex subunit 11. (451 aa)
ENSCANP00000028939eRF1_1 domain-containing protein. (360 aa)
CNOT2CCR4-NOT transcription complex subunit 2. (540 aa)
XRN15'-3' exoribonuclease 1. (1706 aa)
EXOSC9Exosome component 9. (456 aa)
DHX34DExH-box helicase 34. (1143 aa)
NCBP1Nuclear cap binding protein subunit 1. (790 aa)
EXOSC3Exosome component 3. (275 aa)
ENSCANP00000026116Uncharacterized protein. (130 aa)
DIS3L2DIS3 like 3'-5' exoribonuclease 2; Belongs to the RNR ribonuclease family. (831 aa)
NT5C3B5'-nucleotidase; Belongs to the pyrimidine 5'-nucleotidase family. (300 aa)
TUT4Terminal uridylyl transferase 4. (1649 aa)
LOC105517234Uncharacterized protein. (146 aa)
ENSCANP00000025588Uncharacterized protein. (242 aa)
DCP1BDecapping mRNA 1B. (616 aa)
ETF1Uncharacterized protein. (329 aa)
TUT7Terminal uridylyl transferase 7. (1490 aa)
EXOSC4Exosome component 4. (245 aa)
GSPT1G1 to S phase transition 1. (415 aa)
MTPAPMitochondrial poly(A) polymerase. (582 aa)
LSM7LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated. (103 aa)
CSDE1Uncharacterized protein. (844 aa)
MAGOHMago homolog, exon junction complex subunit. (146 aa)
SMG1SMG1 nonsense mediated mRNA decay associated PI3K related kinase; Belongs to the PI3/PI4-kinase family. (2495 aa)
SMG8SMG8 nonsense mediated mRNA decay factor. (991 aa)
LOC105518317Uncharacterized protein. (380 aa)
HELZ2Helicase with zinc finger 2. (2649 aa)
PAN3PAN2-PAN3 deadenylation complex subunit PAN3; Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA deca [...] (855 aa)
LOC105512634Uncharacterized protein. (231 aa)
UPF3AUPF3A regulator of nonsense mediated mRNA decay. (255 aa)
SWT1SWT1 RNA endoribonuclease homolog. (900 aa)
ZCCHC7Zinc finger CCHC-type containing 7. (543 aa)
RC3H1Ring finger and CCCH-type domains 1. (1134 aa)
NOCTEndo/exonuclease/phosphatase domain-containing protein. (431 aa)
DCPSDecapping enzyme, scavenger. (339 aa)
SMG6SMG6 nonsense mediated mRNA decay factor. (1389 aa)
ZFP36L1ZFP36 ring finger protein like 1. (338 aa)
ATMSerine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3056 aa)
LOC105504658Uncharacterized protein. (571 aa)
CTIFCap binding complex dependent translation initiation factor. (600 aa)
DCP2Decapping mRNA 2. (420 aa)
ENSCANP00000013556RRM domain-containing protein. (264 aa)
ENSCANP00000013382RL10P_insert domain-containing protein. (217 aa)
UPF1UPF1 RNA helicase and ATPase. (1079 aa)
MAGOHBMago homolog B, exon junction complex subunit. (148 aa)
TTC37Tetratricopeptide repeat domain 37. (1563 aa)
CNOT4CCR4-NOT transcription complex subunit 4. (713 aa)
ENSCANP00000011836Uncharacterized protein. (288 aa)
SMG5SMG5 nonsense mediated mRNA decay factor. (1005 aa)
UPF3BUPF3B regulator of nonsense mediated mRNA decay. (318 aa)
PARNPoly(A)-specific ribonuclease. (620 aa)
LOC105512457HTH La-type RNA-binding domain-containing protein. (369 aa)
EDC3Enhancer of mRNA decapping 3. (508 aa)
CNOT6LCCR4-NOT transcription complex subunit 6 like. (559 aa)
SSBSmall RNA binding exonuclease protection factor La. (405 aa)
CNOT6CCR4-NOT transcription complex subunit 6. (557 aa)
ENSCANP00000007202R3H domain-containing protein. (192 aa)
PABPC1Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (640 aa)
PELOProtein pelota homolog; May function in recognizing stalled ribosomes and triggering endonucleolytic cleavage of the mRNA, a mechanism to release non- functional ribosomes and degrade damaged mRNAs. (385 aa)
PYM1Mago-bind domain-containing protein. (204 aa)
ENSCANP00000005866Mago-bind domain-containing protein. (219 aa)
LSM1U6 snRNA-associated Sm-like protein LSm1; Plays a role in the degradation of histone mRNAs, the only eukaryotic mRNAs that are not polyadenylated. Probably also part of an LSm subunits-containing complex involved in the general process of mRNA degradation. (133 aa)
PAN2PAN2-PAN3 deadenylation complex catalytic subunit PAN2; Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent [...] (1187 aa)
SMG7SMG7 nonsense mediated mRNA decay factor. (1145 aa)
SAMD4BSterile alpha motif domain containing 4B. (694 aa)
LRRC27Leucine rich repeat containing 27. (529 aa)
EIF3EEukaryotic translation initiation factor 3 subunit E; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] (458 aa)
CNOT3CCR4-NOT transcription complex subunit 3. (751 aa)
PATL2PAT1 homolog 2. (538 aa)
ENSCANP00000003829PABC domain-containing protein. (284 aa)
NBASNeuroblastoma amplified sequence. (2315 aa)
ZFP36ZFP36 ring finger protein. (332 aa)
MLH1MutL homolog 1. (743 aa)
DIS3DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease; Belongs to the RNR ribonuclease family. (958 aa)
CASC3CASC3 exon junction complex subunit. (704 aa)
NBDYNegative regulator of P-body association. (68 aa)
LOC105502228Ribosome assembly factor mrt4; Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes. (225 aa)
LOC105523459Btz domain-containing protein. (766 aa)
MRTO4Ribosome assembly factor mrt4; Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes. (239 aa)
DCP1ADecapping mRNA 1A. (582 aa)
Your Current Organism:
Colobus angolensis
NCBI taxonomy Id: 336983
Other names: C. angolensis palliatus, Colobus angolensis palliatus
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