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HIRA HIRA BMP4 BMP4 WNT10B WNT10B SOX8 SOX8 AKT1 AKT1 BGLAP BGLAP SPP1 SPP1 ENSCANP00000015194 ENSCANP00000015194 GLI3 GLI3 GDF2 GDF2 SMAD5 SMAD5 ENSCANP00000016154 ENSCANP00000016154 SP7 SP7 ENSCANP00000017579 ENSCANP00000017579 DNAJC13 DNAJC13 SMAD1 SMAD1 CYP24A1 CYP24A1 FGF9 FGF9 LOC105516434 LOC105516434 ATP5F1B ATP5F1B DLX5 DLX5 ITGA11 ITGA11 IBSP IBSP RUNX2 RUNX2 ALYREF ALYREF SNRNP200 SNRNP200 ENSCANP00000022502 ENSCANP00000022502 COL1A1 COL1A1 BMP3 BMP3 MEF2D MEF2D LOC105516537 LOC105516537 SNAI1 SNAI1 HAND2 HAND2 IGFBP5 IGFBP5 ACHE ACHE RSPO2 RSPO2 LIMD1 LIMD1 UCMA UCMA PHB PHB WWOX WWOX WNT3A WNT3A CREB3L1 CREB3L1 SMAD4 SMAD4 CLTC CLTC WWTR1 WWTR1 SHH SHH SEMA7A SEMA7A SHOX2 SHOX2 MSX2 MSX2 MYOC MYOC PENK PENK BMPR2 BMPR2 DDX21 DDX21 PTH1R PTH1R TNC TNC RRAS2 RRAS2 ADAR ADAR LOC105502827 LOC105502827 EPHA2 EPHA2 TNN TNN IFT80 IFT80 ENSCANP00000035234 ENSCANP00000035234 CTHRC1 CTHRC1 LOX LOX CCN4 CCN4 HSPE1 HSPE1 MRC2 MRC2 TP53INP2 TP53INP2 ENSCANP00000038012 ENSCANP00000038012 SIRT7 SIRT7 RDH14 RDH14 GLI2 GLI2 LRP5 LRP5 FASN FASN ENSCANP00000039262 ENSCANP00000039262 MAPK14 MAPK14 GLI1 GLI1 COL6A1 COL6A1 ASF1A ASF1A SFRP1 SFRP1 DHH DHH LEF1 LEF1 SMAD3 SMAD3 JUNB JUNB AXIN2 AXIN2 MAPK11 MAPK11 LOC105506133 LOC105506133 MEN1 MEN1 MYBBP1A MYBBP1A HOXA2 HOXA2 TMEM119 TMEM119 HSD17B4 HSD17B4 IHH IHH CLEC5A CLEC5A ENSCANP00000003670 ENSCANP00000003670 NOG NOG RRBP1 RRBP1 GTPBP4 GTPBP4 CCN1 CCN1 LGR4 LGR4 IGF2 IGF2 ENSCANP00000005277 ENSCANP00000005277 GDF10 GDF10 LOC105500754 LOC105500754 SMO SMO MEF2C MEF2C MAP2K6 MAP2K6 HNRNPU HNRNPU FHL2 FHL2 IGFBP3 IGFBP3 SYNCRIP SYNCRIP BMPR1B BMPR1B GLIS1 GLIS1 BMP6 BMP6 ENSCANP00000009344 ENSCANP00000009344 SATB2 SATB2 WNT3 WNT3 ALPL ALPL COL11A2 COL11A2 CTNNB1 CTNNB1 WNT11 WNT11 SNAI2 SNAI2 GABBR1 GABBR1 BMP2 BMP2 BMPR1A BMPR1A
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
HIRAProtein HIRA; Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle; Belongs to the WD repeat HIR1 family. (1017 aa)
BMP4Bone morphogenetic protein 4. (408 aa)
WNT10BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa)
SOX8SRY-box transcription factor 8. (384 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (488 aa)
BGLAPOsteocalcin; Binds strongly to apatite and calcium. (100 aa)
SPP1Secreted phosphoprotein 1. (314 aa)
ENSCANP00000015194Uncharacterized protein; Belongs to the GroES chaperonin family. (93 aa)
GLI3GLI family zinc finger 3. (1580 aa)
GDF2Growth differentiation factor 2. (429 aa)
SMAD5Mothers against decapentaplegic homolog. (465 aa)
ENSCANP00000016154Uncharacterized protein. (82 aa)
SP7Sp7 transcription factor. (431 aa)
ENSCANP00000017579SEC63 domain-containing protein. (264 aa)
DNAJC13J domain-containing protein. (2192 aa)
SMAD1Mothers against decapentaplegic homolog. (465 aa)
CYP24A1Cytochrome P450 family 24 subfamily A member 1; Belongs to the cytochrome P450 family. (514 aa)
FGF9Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
LOC105516434Uncharacterized protein. (118 aa)
ATP5F1BATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. (529 aa)
DLX5Distal-less homeobox 5. (289 aa)
ITGA11Integrin subunit alpha 11; Belongs to the integrin alpha chain family. (1191 aa)
IBSPIntegrin binding sialoprotein. (317 aa)
RUNX2RUNX family transcription factor 2. (475 aa)
ALYREFAly/REF export factor. (265 aa)
SNRNP200Small nuclear ribonucleoprotein U5 subunit 200. (2055 aa)
ENSCANP00000022502Prohibitin. (185 aa)
COL1A1Collagen type I alpha 1 chain. (1464 aa)
BMP3Bone morphogenetic protein 3; Belongs to the TGF-beta family. (472 aa)
MEF2DMyocyte enhancer factor 2D. (521 aa)
LOC105516537Uncharacterized protein. (698 aa)
SNAI1Snail family transcriptional repressor 1. (264 aa)
HAND2Uncharacterized protein. (66 aa)
IGFBP5Insulin like growth factor binding protein 5. (272 aa)
ACHECarboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (618 aa)
RSPO2R-spondin 2. (243 aa)
LIMD1LIM domains containing 1. (677 aa)
UCMAUpper zone of growth plate and cartilage matrix associated. (138 aa)
PHBProhibitin. (272 aa)
WWOXWW domain containing oxidoreductase. (414 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
CREB3L1cAMP responsive element binding protein 3 like 1. (519 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
CLTCClathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1679 aa)
WWTR1WW domain containing transcription regulator 1. (400 aa)
SHHSonic hedgehog signaling molecule. (390 aa)
SEMA7ASemaphorin 7A (John Milton Hagen blood group); Belongs to the semaphorin family. (668 aa)
SHOX2Short stature homeobox 2. (221 aa)
MSX2Msh homeobox 2. (267 aa)
MYOCMyocilin. (505 aa)
PENKProenkephalin. (267 aa)
BMPR2Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1030 aa)
DDX21DExD-box helicase 21. (781 aa)
PTH1RParathyroid hormone 1 receptor; Belongs to the G-protein coupled receptor 2 family. (592 aa)
TNCTenascin C. (2201 aa)
RRAS2RAS related 2. (179 aa)
ADARAdenosine deaminase RNA specific. (1225 aa)
LOC105502827Prohibitin. (244 aa)
EPHA2EPH receptor A2. (976 aa)
TNNTenascin N. (1299 aa)
IFT80Intraflagellar transport 80. (777 aa)
ENSCANP00000035234Prohibitin. (260 aa)
CTHRC1Collagen triple helix repeat containing 1. (147 aa)
LOXLysyl oxidase. (417 aa)
CCN4Cellular communication network factor 4. (367 aa)
HSPE110 kDa heat shock protein, mitochondrial. (102 aa)
MRC2Mannose receptor C type 2. (1479 aa)
TP53INP2Tumor protein p53 inducible nuclear protein 2. (179 aa)
ENSCANP00000038012Prohibitin. (190 aa)
SIRT7Sirtuin 7. (361 aa)
RDH14Retinol dehydrogenase 14; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (268 aa)
GLI2GLI family zinc finger 2. (1585 aa)
LRP5Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1611 aa)
FASNFatty acid synthase. (2510 aa)
ENSCANP00000039262Uncharacterized protein; Belongs to the GroES chaperonin family. (87 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
GLI1GLI family zinc finger 1. (1065 aa)
COL6A1Collagen type VI alpha 1 chain. (935 aa)
ASF1AAnti-silencing function 1A histone chaperone. (204 aa)
SFRP1Secreted frizzled related protein 1. (314 aa)
DHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (396 aa)
LEF1Lymphoid enhancer binding factor 1. (399 aa)
SMAD3Mothers against decapentaplegic homolog. (425 aa)
JUNBJunB proto-oncogene, AP-1 transcription factor subunit. (347 aa)
AXIN2Axin 2. (843 aa)
MAPK11Mitogen-activated protein kinase. (306 aa)
LOC105506133Uncharacterized protein; Belongs to the GroES chaperonin family. (102 aa)
MEN1Menin 1. (610 aa)
MYBBP1AMYB binding protein 1a. (1226 aa)
HOXA2Homeobox A2. (374 aa)
TMEM119Transmembrane protein 119. (283 aa)
HSD17B4Hydroxysteroid 17-beta dehydrogenase 4. (754 aa)
IHHIndian hedgehog signaling molecule. (373 aa)
CLEC5AC-type lectin domain containing 5A. (188 aa)
ENSCANP00000003670Uncharacterized protein; Belongs to the GroES chaperonin family. (102 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
RRBP1Ribosome binding protein 1. (1400 aa)
GTPBP4Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily. (635 aa)
CCN1Cellular communication network factor 1. (381 aa)
LGR4Leucine rich repeat containing G protein-coupled receptor 4. (932 aa)
IGF2Insulin like growth factor 2. (236 aa)
ENSCANP00000005277Uncharacterized protein; Belongs to the GroES chaperonin family. (102 aa)
GDF10Bone morphogenetic protein 3; Belongs to the TGF-beta family. (474 aa)
LOC10550075410 kDa heat shock protein, mitochondrial. (102 aa)
SMOSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (768 aa)
MEF2CMyocyte enhancer factor 2C. (483 aa)
MAP2K6Mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (334 aa)
HNRNPUHeterogeneous nuclear ribonucleoprotein U. (821 aa)
FHL2Four and a half LIM domains 2. (363 aa)
IGFBP3Insulin like growth factor binding protein 3. (189 aa)
SYNCRIPSynaptotagmin binding cytoplasmic RNA interacting protein. (562 aa)
BMPR1BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
GLIS1GLIS family zinc finger 1. (795 aa)
BMP6Bone morphogenetic protein 6. (331 aa)
ENSCANP00000009344Uncharacterized protein. (627 aa)
SATB2DNA-binding protein SATB. (733 aa)
WNT3Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa)
ALPLAlkaline phosphatase. (524 aa)
COL11A2Collagen type XI alpha 2 chain. (1613 aa)
CTNNB1Catenin beta 1. (781 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (330 aa)
SNAI2Snail family transcriptional repressor 2. (268 aa)
GABBR1Gamma-aminobutyric acid type B receptor subunit 1. (963 aa)
BMP2Bone morphogenetic protein 2. (396 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
Your Current Organism:
Colobus angolensis
NCBI taxonomy Id: 336983
Other names: C. angolensis palliatus, Colobus angolensis palliatus
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