STRINGSTRING
NPHS2 NPHS2 SALL1 SALL1 PTCH1 PTCH1 RDH10 RDH10 NKX3-1 NKX3-1 ENSCANP00000009344 ENSCANP00000009344 FGF8 FGF8 PDGFRB PDGFRB WNT4 WNT4 ENSCANP00000026961 ENSCANP00000026961 WT1 WT1 SMAD4 SMAD4 FBN1 FBN1 AGTR2 AGTR2 ENSCANP00000030255 ENSCANP00000030255 SHH SHH GDNF GDNF ENSCANP00000033948 ENSCANP00000033948 SOX9 SOX9 CALB1 CALB1 SOX17 SOX17 PKD1 PKD1 FRAS1 FRAS1 ENSCANP00000037159 ENSCANP00000037159 OSR2 OSR2 OSR1 OSR1 ITGA8 ITGA8 STAT1 STAT1 CTNNB1 CTNNB1 FOXJ1 FOXJ1 SIX2 SIX2 BMP4 BMP4 GDF6 GDF6 IRX1 IRX1 SOX8 SOX8 KIF26B KIF26B GLI3 GLI3 PDGFB PDGFB PAX2 PAX2 ENSCANP00000016929 ENSCANP00000016929 EYA1 EYA1 NIPBL NIPBL ID3 ID3 TFAP2B TFAP2B SIX4 SIX4 SIX1 SIX1 GREB1 GREB1 HOXC11 HOXC11 APH1A APH1A BMP7 BMP7 GATA3 GATA3 ROBO2 ROBO2 CTSH CTSH CD34 CD34 UMOD UMOD RET RET FGF10 FGF10 AQP2 AQP2 FMN1 FMN1 GREB1L GREB1L IRX3 IRX3 HOXA11 HOXA11 SMO SMO LGR4 LGR4 BCL2 BCL2 WNT7B WNT7B LAMB2 LAMB2 DLG5 DLG5 AKR1B1 AKR1B1 GDF11 GDF11 TCF21 TCF21 LOC105515551 LOC105515551 WNT9B WNT9B PKD2 PKD2 SPRY1 SPRY1 CITED1 CITED1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NPHS2NPHS2 stomatin family member, podocin. (383 aa)
SALL1Spalt like transcription factor 1. (1318 aa)
PTCH1Patched 1. (1449 aa)
RDH10Retinol dehydrogenase 10. (176 aa)
NKX3-1NK3 homeobox 1. (232 aa)
ENSCANP00000009344Uncharacterized protein. (627 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (222 aa)
PDGFRBPlatelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1106 aa)
WNT4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (345 aa)
ENSCANP00000026961Aldo_ket_red domain-containing protein. (235 aa)
WT1WT1 transcription factor. (517 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
FBN1Fibrillin 1. (2816 aa)
AGTR2Angiotensin II receptor type 2; Belongs to the G-protein coupled receptor 1 family. (363 aa)
ENSCANP00000030255Fork-head domain-containing protein. (189 aa)
SHHSonic hedgehog signaling molecule. (390 aa)
GDNFGlial cell derived neurotrophic factor. (228 aa)
ENSCANP00000033948Homeobox domain-containing protein. (141 aa)
SOX9SRY-box transcription factor 9. (509 aa)
CALB1Calbindin 1. (261 aa)
SOX17SRY-box transcription factor 17. (412 aa)
PKD1Polycystin 1, transient receptor potential channel interacting. (4053 aa)
FRAS1Fraser extracellular matrix complex subunit 1. (4011 aa)
ENSCANP00000037159Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (113 aa)
OSR2Odd-skipped related transciption factor 2. (418 aa)
OSR1Odd-skipped related transcription factor 1. (266 aa)
ITGA8Integrin subunit alpha 8; Belongs to the integrin alpha chain family. (1052 aa)
STAT1Signal transducer and activator of transcription. (765 aa)
CTNNB1Catenin beta 1. (781 aa)
FOXJ1Forkhead box J1. (389 aa)
SIX2SIX homeobox 2. (292 aa)
BMP4Bone morphogenetic protein 4. (408 aa)
GDF6Growth differentiation factor 6. (455 aa)
IRX1Iroquois homeobox 1. (460 aa)
SOX8SRY-box transcription factor 8. (384 aa)
KIF26BKinesin family member 26B; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (2023 aa)
GLI3GLI family zinc finger 3. (1580 aa)
PDGFBPlatelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (220 aa)
PAX2Paired box 2. (388 aa)
ENSCANP00000016929Aldo_ket_red domain-containing protein. (303 aa)
EYA1Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (592 aa)
NIPBLNipped-B protein. (2804 aa)
ID3Inhibitor of DNA binding 3, HLH protein. (119 aa)
TFAP2BTranscription factor AP-2 beta. (460 aa)
SIX4SIX homeobox 4. (780 aa)
SIX1SIX homeobox 1. (284 aa)
GREB1Growth regulating estrogen receptor binding 1. (1949 aa)
HOXC11Homeobox C11. (304 aa)
APH1AAph-1 homolog A, gamma-secretase subunit. (265 aa)
BMP7Bone morphogenetic protein 7. (431 aa)
GATA3GATA binding protein 3. (444 aa)
ROBO2Roundabout guidance receptor 2. (1439 aa)
CTSHCathepsin H; Belongs to the peptidase C1 family. (331 aa)
CD34CD34 molecule. (385 aa)
UMODUromodulin. (674 aa)
RETProto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands. (1089 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
AQP2Aquaporin 2; Belongs to the MIP/aquaporin (TC 1.A.8) family. (271 aa)
FMN1Formin 1. (1415 aa)
GREB1LGREB1 like retinoic acid receptor coactivator. (1924 aa)
IRX3Iroquois homeobox 3. (411 aa)
HOXA11Homeobox A11. (312 aa)
SMOSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (768 aa)
LGR4Leucine rich repeat containing G protein-coupled receptor 4. (932 aa)
BCL2BCL2 apoptosis regulator. (239 aa)
WNT7BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa)
LAMB2Laminin subunit beta 2. (1798 aa)
DLG5Discs large MAGUK scaffold protein 5; Belongs to the MAGUK family. (1896 aa)
AKR1B1Aldo-keto reductase family 1 member B. (316 aa)
GDF11Growth differentiation factor 11. (345 aa)
TCF21Transcription factor 21. (179 aa)
LOC105515551Aldo_ket_red domain-containing protein. (277 aa)
WNT9BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (350 aa)
PKD2Polycystin 2, transient receptor potential cation channel. (780 aa)
SPRY1Sprouty RTK signaling antagonist 1. (319 aa)
CITED1Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1. (219 aa)
Your Current Organism:
Colobus angolensis
NCBI taxonomy Id: 336983
Other names: C. angolensis palliatus, Colobus angolensis palliatus
Server load: low (22%) [HD]