STRINGSTRING
ADA ADA HTRA1 HTRA1 BMPR2 BMPR2 BPTF BPTF EGLN1 EGLN1 EOMES EOMES DAZAP1 DAZAP1 FOSL1 FOSL1 ZNF568 ZNF568 NODAL NODAL NDP NDP IL10 IL10 CDX2 CDX2 ST14 ST14 PKD1 PKD1 CDX4 CDX4 PTK2 PTK2 CUL7 CUL7 TRIM28 TRIM28 ETNK2 ETNK2 VASH2 VASH2 PCDH12 PCDH12 ADAM19 ADAM19 EPOR EPOR DLX3 DLX3 MAPK14 MAPK14 GRB2 GRB2 SETD2 SETD2 NSDHL NSDHL CITED1 CITED1 ITGB8 ITGB8 LOC105516507 LOC105516507 LEF1 LEF1 RTL1 RTL1 ENSCANP00000000656 ENSCANP00000000656 MED1 MED1 JUNB JUNB APELA APELA GJB3 GJB3 HEY1 HEY1 PKD2 PKD2 LEP LEP MEN1 MEN1 SOX15 SOX15 LIF LIF LOC105522500 LOC105522500 VDR VDR LHX3 LHX3 CCNF CCNF BIRC2 BIRC2 SOCS3 SOCS3 CCN1 CCN1 WNT7B WNT7B ARNT ARNT PRDM1 PRDM1 LHX4 LHX4 TCF23 TCF23 LOC105503463 LOC105503463 IGF2 IGF2 LDOC1 LDOC1 ASH1L ASH1L PLAC1 PLAC1 ENSCANP00000006272 ENSCANP00000006272 TTPAL TTPAL GCM1 GCM1 STK3 STK3 LOC105511615 LOC105511615 BMP5 BMP5 PLK4 PLK4 NOTCH2 NOTCH2 RSPO3 RSPO3 ALKBH1 ALKBH1 HSD17B2 HSD17B2 NR2F2 NR2F2 GHRL GHRL CSF2 CSF2 FBN2 FBN2 CASP8 CASP8 STC1 STC1 CYP27B1 CYP27B1 TFEB TFEB TTPA TTPA AKT1 AKT1 SPP1 SPP1 HECTD1 HECTD1 ENSCANP00000015284 ENSCANP00000015284 PLCD3 PLCD3 PDGFB PDGFB ZFP36L1 ZFP36L1 NCOA1 NCOA1 STOX2 STOX2 MAP3K4 MAP3K4 WNT2 WNT2 SPINT1 SPINT1 PEG10 PEG10 ETV2 ETV2 PPARD PPARD FGFR2 FGFR2 BIRC6 BIRC6 PTGS2 PTGS2 OVOL2 OVOL2 CCDC134 CCDC134 CITED2 CITED2 E2F7 E2F7 TPPP3 TPPP3 TAF10 TAF10 HEY2 HEY2 SP3 SP3 EPAS1 EPAS1 PHLDA2 PHLDA2 MDFI MDFI BMP7 BMP7 HNF1A HNF1A LOC105521110 LOC105521110 BSG BSG FBXW8 FBXW8 ADM ADM CDKN1B CDKN1B SNAI1 SNAI1 E2F8 E2F8 VASH1 VASH1 HAND1 HAND1 MAPK1 MAPK1 ZFAT ZFAT RTL5 RTL5 HIF1A HIF1A FZD5 FZD5 LOC105519708 LOC105519708 GRHL2 GRHL2 HS6ST1 HS6ST1 LOC105515431 LOC105515431 GATA2 GATA2 TMED2 TMED2 GHSR GHSR PTN PTN RBM15 RBM15
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ADAUncharacterized protein. (424 aa)
HTRA1HtrA serine peptidase 1. (384 aa)
BMPR2Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1030 aa)
BPTFBromodomain PHD finger transcription factor. (2856 aa)
EGLN1Fe2OG dioxygenase domain-containing protein. (128 aa)
EOMESEomesodermin. (705 aa)
DAZAP1DAZ associated protein 1. (408 aa)
FOSL1FOS like 1, AP-1 transcription factor subunit. (271 aa)
ZNF568Zinc finger protein 568. (646 aa)
NODALNodal growth differentiation factor. (347 aa)
NDPNorrin cystine knot growth factor NDP. (133 aa)
IL10Interleukin 10. (178 aa)
CDX2Caudal type homeobox 2. (313 aa)
ST14Suppressor of tumorigenicity 14 protein homolog; Degrades extracellular matrix. Belongs to the peptidase S1 family. (849 aa)
PKD1Polycystin 1, transient receptor potential channel interacting. (4053 aa)
CDX4Caudal type homeobox 4. (284 aa)
PTK2Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1096 aa)
CUL7Cullin 7; Belongs to the cullin family. (1697 aa)
TRIM28Tripartite motif containing 28. (823 aa)
ETNK2Ethanolamine kinase 2. (366 aa)
VASH2Vasohibin 2. (311 aa)
PCDH12Protocadherin 12. (1184 aa)
ADAM19ADAM metallopeptidase domain 19. (918 aa)
EPORErythropoietin receptor; Receptor for erythropoietin. (508 aa)
DLX3Distal-less homeobox 3. (287 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
GRB2Uncharacterized protein. (156 aa)
SETD2SET domain containing 2, histone lysine methyltransferase. (2517 aa)
NSDHLNAD(P) dependent steroid dehydrogenase-like; Belongs to the 3-beta-HSD family. (373 aa)
CITED1Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1. (219 aa)
ITGB8Integrin beta; Belongs to the integrin beta chain family. (769 aa)
LOC105516507DUF4939 domain-containing protein. (113 aa)
LEF1Lymphoid enhancer binding factor 1. (399 aa)
RTL1Retrotransposon Gag like 1. (1358 aa)
ENSCANP00000000656Uncharacterized protein. (178 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1576 aa)
JUNBJunB proto-oncogene, AP-1 transcription factor subunit. (347 aa)
APELAApelin receptor early endogenous ligand. (54 aa)
GJB3Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (270 aa)
HEY1Hes related family bHLH transcription factor with YRPW motif 1. (308 aa)
PKD2Polycystin 2, transient receptor potential cation channel. (780 aa)
LEPLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (167 aa)
MEN1Menin 1. (610 aa)
SOX15SRY-box transcription factor 15. (233 aa)
LIFLIF interleukin 6 family cytokine. (204 aa)
LOC105522500IF rod domain-containing protein; Belongs to the intermediate filament family. (397 aa)
VDRVitamin D receptor. (477 aa)
LHX3LIM homeobox 3. (332 aa)
CCNFCyclin F; Belongs to the cyclin family. (742 aa)
BIRC2Baculoviral IAP repeat containing 2. (618 aa)
SOCS3Suppressor of cytokine signaling 3. (225 aa)
CCN1Cellular communication network factor 1. (381 aa)
WNT7BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa)
ARNTAryl hydrocarbon receptor nuclear translocator. (789 aa)
PRDM1PR/SET domain 1. (825 aa)
LHX4LIM homeobox 4. (390 aa)
TCF23Transcription factor 23. (214 aa)
LOC10550346340S ribosomal protein S6; Belongs to the eukaryotic ribosomal protein eS6 family. (249 aa)
IGF2Insulin like growth factor 2. (236 aa)
LDOC1LDOC1 regulator of NFKB signaling. (146 aa)
ASH1LASH1 like histone lysine methyltransferase. (2969 aa)
PLAC1Placenta enriched 1. (212 aa)
ENSCANP0000000627240S ribosomal protein S6; Belongs to the eukaryotic ribosomal protein eS6 family. (229 aa)
TTPALAlpha tocopherol transfer protein like. (342 aa)
GCM1Glial cells missing transcription factor 1. (436 aa)
STK3Serine/threonine kinase 3. (489 aa)
LOC10551161540S ribosomal protein S6; Belongs to the eukaryotic ribosomal protein eS6 family. (216 aa)
BMP5Bone morphogenetic protein 5. (454 aa)
PLK4Polo like kinase 4. (970 aa)
NOTCH2Notch receptor 2. (2471 aa)
RSPO3R-spondin 3. (293 aa)
ALKBH1AlkB homolog 1, histone H2A dioxygenase. (389 aa)
HSD17B2Hydroxysteroid 17-beta dehydrogenase 2; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (387 aa)
NR2F2Nuclear receptor subfamily 2 group F member 2. (366 aa)
GHRLGhrelin and obestatin prepropeptide. (117 aa)
CSF2Colony stimulating factor 2. (144 aa)
FBN2Fibrillin 2. (2912 aa)
CASP8Caspase 8; Belongs to the peptidase C14A family. (538 aa)
STC1Stanniocalcin 1. (247 aa)
CYP27B1Cytochrome P450 family 27 subfamily B member 1; Belongs to the cytochrome P450 family. (509 aa)
TFEBTranscription factor EB. (490 aa)
TTPAAlpha tocopherol transfer protein. (278 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (488 aa)
SPP1Secreted phosphoprotein 1. (314 aa)
HECTD1HECT domain E3 ubiquitin protein ligase 1. (2506 aa)
ENSCANP00000015284GOLD domain-containing protein. (93 aa)
PLCD3Phosphoinositide phospholipase C. (758 aa)
PDGFBPlatelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (220 aa)
ZFP36L1ZFP36 ring finger protein like 1. (338 aa)
NCOA1Nuclear receptor coactivator. (1441 aa)
STOX2Storkhead box 2. (926 aa)
MAP3K4Mitogen-activated protein kinase kinase kinase 4. (1586 aa)
WNT2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (360 aa)
SPINT1Serine peptidase inhibitor, Kunitz type 1. (531 aa)
PEG10Paternally expressed 10. (775 aa)
ETV2ETS domain-containing protein. (155 aa)
PPARDPeroxisome proliferator activated receptor delta. (441 aa)
FGFR2Fibroblast growth factor receptor. (838 aa)
BIRC6Baculoviral IAP repeat containing 6. (4838 aa)
PTGS2Prostaglandin-endoperoxide synthase 2. (604 aa)
OVOL2Ovo like zinc finger 2. (252 aa)
CCDC134Coiled-coil domain containing 134. (229 aa)
CITED2Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2. (278 aa)
E2F7E2F transcription factor 7. (910 aa)
TPPP3Tubulin polymerization promoting protein family member 3. (176 aa)
TAF10Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family. (218 aa)
HEY2Hes related family bHLH transcription factor with YRPW motif 2. (337 aa)
SP3Sp3 transcription factor. (714 aa)
EPAS1Endothelial PAS domain protein 1. (869 aa)
PHLDA2Pleckstrin homology like domain family A member 2. (193 aa)
MDFIMyoD family inhibitor. (246 aa)
BMP7Bone morphogenetic protein 7. (431 aa)
HNF1AHNF1 homeobox A. (662 aa)
LOC105521110Uncharacterized protein. (202 aa)
BSGBasigin (Ok blood group). (373 aa)
FBXW8F-box and WD repeat domain containing 8. (524 aa)
ADMAdrenomedullin. (185 aa)
CDKN1BCyclin dependent kinase inhibitor 1B. (198 aa)
SNAI1Snail family transcriptional repressor 1. (264 aa)
E2F8E2F transcription factor 8. (867 aa)
VASH1Vasohibin 1. (365 aa)
HAND1Heart and neural crest derivatives expressed 1. (215 aa)
MAPK1Mitogen-activated protein kinase. (343 aa)
ZFATZinc finger and AT-hook domain containing. (1250 aa)
RTL5Retrotransposon Gag like 5. (567 aa)
HIF1AHypoxia inducible factor 1 subunit alpha. (827 aa)
FZD5Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family. (585 aa)
LOC105519708A_deaminase domain-containing protein. (284 aa)
GRHL2Grainyhead like transcription factor 2. (625 aa)
HS6ST1Heparan-sulfate 6-O-sulfotransferase; 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate. (360 aa)
LOC10551543140S ribosomal protein S6; Belongs to the eukaryotic ribosomal protein eS6 family. (249 aa)
GATA2GATA binding protein 2. (480 aa)
TMED2Transmembrane p24 trafficking protein 2. (116 aa)
GHSRGrowth hormone secretagogue receptor; Belongs to the G-protein coupled receptor 1 family. (366 aa)
PTNPleiotrophin. (172 aa)
RBM15RNA binding motif protein 15. (980 aa)
Your Current Organism:
Colobus angolensis
NCBI taxonomy Id: 336983
Other names: C. angolensis palliatus, Colobus angolensis palliatus
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