STRINGSTRING
COL2A1 COL2A1 PTH1R PTH1R TRIP11 TRIP11 EXT2 EXT2 MAPK14 MAPK14 SOX6 SOX6 WNT7A WNT7A FGF9 FGF9 SFRP2 SFRP2 RUNX1 RUNX1 HMGA2 HMGA2 ARID5A ARID5A GLI3 GLI3 GPLD1 GPLD1 WNT5B WNT5B CHSY1 CHSY1 CYTL1 CYTL1 WNT10B WNT10B BMP4 BMP4 SIX2 SIX2 BMPR1A BMPR1A SOX5 SOX5 SERPINH1 SERPINH1 BMP2 BMP2 SCUBE2 SCUBE2 CTNNB1 CTNNB1 COL11A2 COL11A2 TGFB1 TGFB1 BMPR1B BMPR1B IMPAD1 IMPAD1 MEF2C MEF2C HOXA11 HOXA11 COMP COMP ATF2 ATF2 TSKU TSKU TGFBR2 TGFBR2 LOC105517826 LOC105517826 IHH IHH AXIN2 AXIN2 MATN1 MATN1 ADAMTS7 ADAMTS7 RARG RARG OSR1 OSR1 FGF18 FGF18 OSR2 OSR2 ANXA6 ANXA6 LTBP3 LTBP3 ACAN ACAN SMPD3 SMPD3 SLC39A14 SLC39A14 IFT80 IFT80 SULF2 SULF2 GDF5 GDF5 ADAMTS12 ADAMTS12 SULF1 SULF1 MUSTN1 MUSTN1 CCN3 CCN3 HIF1A HIF1A CHST11 CHST11 RUNX3 RUNX3 COL27A1 COL27A1 SHOX2 SHOX2 ECM1 ECM1 BMPR2 BMPR2 CREB3L2 CREB3L2 TGFBI TGFBI SNX19 SNX19 NPPC NPPC WNT2B WNT2B FGFR3 FGFR3 COL11A1 COL11A1 ENSCANP00000033948 ENSCANP00000033948 SOX9 SOX9 NFIB NFIB TWSG1 TWSG1 COL3A1 COL3A1 MEX3C MEX3C RUNX2 RUNX2 CCN2 CCN2 EIF2AK3 EIF2AK3 EXT1 EXT1 MEF2D MEF2D
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
COL2A1Collagen type II alpha 1 chain. (1487 aa)
PTH1RParathyroid hormone 1 receptor; Belongs to the G-protein coupled receptor 2 family. (592 aa)
TRIP11Thyroid hormone receptor interactor 11. (1938 aa)
EXT2Exostosin glycosyltransferase 2; Belongs to the glycosyltransferase 47 family. (751 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
SOX6SRY-box transcription factor 6. (828 aa)
WNT7AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (349 aa)
FGF9Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
SFRP2Secreted frizzled related protein 2. (295 aa)
RUNX1Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (455 aa)
HMGA2High mobility group AT-hook 2. (147 aa)
ARID5AAT-rich interaction domain 5A. (592 aa)
GLI3GLI family zinc finger 3. (1580 aa)
GPLD1Glycosylphosphatidylinositol specific phospholipase D1. (841 aa)
WNT5BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (359 aa)
CHSY1Hexosyltransferase. (716 aa)
CYTL1Cytokine like 1. (136 aa)
WNT10BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa)
BMP4Bone morphogenetic protein 4. (408 aa)
SIX2SIX homeobox 2. (292 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
SOX5SRY-box transcription factor 5. (763 aa)
SERPINH1Serpin family H member 1; Belongs to the serpin family. (418 aa)
BMP2Bone morphogenetic protein 2. (396 aa)
SCUBE2Signal peptide, CUB domain and EGF like domain containing 2. (954 aa)
CTNNB1Catenin beta 1. (781 aa)
COL11A2Collagen type XI alpha 2 chain. (1613 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (336 aa)
BMPR1BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
IMPAD1Inositol monophosphatase domain containing 1. (359 aa)
MEF2CMyocyte enhancer factor 2C. (483 aa)
HOXA11Homeobox A11. (312 aa)
COMPCartilage oligomeric matrix protein. (757 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa)
TSKUTsukushi, small leucine rich proteoglycan. (353 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa)
LOC105517826SERPIN domain-containing protein; Belongs to the serpin family. (382 aa)
IHHIndian hedgehog signaling molecule. (373 aa)
AXIN2Axin 2. (843 aa)
MATN1Matrilin 1. (496 aa)
ADAMTS7ADAM metallopeptidase with thrombospondin type 1 motif 7. (1676 aa)
RARGRetinoic acid receptor gamma. (461 aa)
OSR1Odd-skipped related transcription factor 1. (266 aa)
FGF18Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
OSR2Odd-skipped related transciption factor 2. (418 aa)
ANXA6Annexin. (683 aa)
LTBP3Latent transforming growth factor beta binding protein 3. (1127 aa)
ACANAggrecan. (2167 aa)
SMPD3Sphingomyelin phosphodiesterase 3. (655 aa)
SLC39A14Solute carrier family 39 member 14. (490 aa)
IFT80Intraflagellar transport 80. (777 aa)
SULF2Extracellular sulfatase; Exhibits arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity. It can remove sulfate from the C- 6 position of glucosamine within specific subregions of intact heparin. Belongs to the sulfatase family. (870 aa)
GDF5Growth differentiation factor 5. (499 aa)
ADAMTS12ADAM metallopeptidase with thrombospondin type 1 motif 12. (1598 aa)
SULF1Extracellular sulfatase; Exhibits arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity. It can remove sulfate from the C- 6 position of glucosamine within specific subregions of intact heparin. Belongs to the sulfatase family. (873 aa)
MUSTN1Uncharacterized protein. (87 aa)
CCN3Cellular communication network factor 3. (357 aa)
HIF1AHypoxia inducible factor 1 subunit alpha. (827 aa)
CHST11Carbohydrate sulfotransferase. (352 aa)
RUNX3Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (366 aa)
COL27A1Collagen type XXVII alpha 1 chain. (1839 aa)
SHOX2Short stature homeobox 2. (221 aa)
ECM1Extracellular matrix protein 1. (567 aa)
BMPR2Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1030 aa)
CREB3L2cAMP responsive element binding protein 3 like 2. (461 aa)
TGFBITransforming growth factor beta induced. (690 aa)
SNX19Sorting nexin 19. (992 aa)
NPPCNatriuretic peptide C. (126 aa)
WNT2BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (391 aa)
FGFR3Fibroblast growth factor receptor. (808 aa)
COL11A1Collagen type XI alpha 1 chain. (1764 aa)
ENSCANP00000033948Homeobox domain-containing protein. (141 aa)
SOX9SRY-box transcription factor 9. (509 aa)
NFIBNuclear factor 1; Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. (570 aa)
TWSG1Twisted gastrulation BMP signaling modulator 1. (223 aa)
COL3A1Collagen type III alpha 1 chain. (1466 aa)
MEX3CMex-3 RNA binding family member C. (570 aa)
RUNX2RUNX family transcription factor 2. (475 aa)
CCN2Cellular communication network factor 2. (301 aa)
EIF2AK3Eukaryotic translation initiation factor 2 alpha kinase 3. (965 aa)
EXT1Exostosin glycosyltransferase 1; Belongs to the glycosyltransferase 47 family. (746 aa)
MEF2DMyocyte enhancer factor 2D. (521 aa)
Your Current Organism:
Colobus angolensis
NCBI taxonomy Id: 336983
Other names: C. angolensis palliatus, Colobus angolensis palliatus
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