STRINGSTRING
HEY1 HEY1 TGFBR2 TGFBR2 CCN1 CCN1 DCHS1 DCHS1 OLFM1 OLFM1 ACVR1 ACVR1 BMP2 BMP2 BMPR1A BMPR1A EFNA1 EFNA1 MDM4 MDM4 TBX5 TBX5 TGFB2 TGFB2 HEY2 HEY2 SLIT3 SLIT3 NOTCH1 NOTCH1 SMAD4 SMAD4 BMPR2 BMPR2 ENSCANP00000032612 ENSCANP00000032612 HEYL HEYL ENSCANP00000036326 ENSCANP00000036326 GATA4 GATA4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
HEY1Hes related family bHLH transcription factor with YRPW motif 1. (308 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa)
CCN1Cellular communication network factor 1. (381 aa)
DCHS1Dachsous cadherin-related 1. (3302 aa)
OLFM1Olfactomedin 1. (467 aa)
ACVR1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (509 aa)
BMP2Bone morphogenetic protein 2. (396 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
EFNA1Ephrin A1; Belongs to the ephrin family. (205 aa)
MDM4MDM4 regulator of p53. (340 aa)
TBX5T-box transcription factor 5. (518 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
HEY2Hes related family bHLH transcription factor with YRPW motif 2. (337 aa)
SLIT3Slit guidance ligand 3. (1500 aa)
NOTCH1Notch receptor 1. (2559 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
BMPR2Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1030 aa)
ENSCANP00000032612SWIB domain-containing protein. (72 aa)
HEYLHes related family bHLH transcription factor with YRPW motif like. (328 aa)
ENSCANP00000036326Uncharacterized protein. (144 aa)
GATA4GATA binding protein 4. (236 aa)
Your Current Organism:
Colobus angolensis
NCBI taxonomy Id: 336983
Other names: C. angolensis palliatus, Colobus angolensis palliatus
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