STRINGSTRING
LOC105515029 LOC105515029 MAP3K10 MAP3K10 MTA2 MTA2 PIAS1 PIAS1 PARP10 PARP10 CBX4 CBX4 SCAI SCAI CNOT7 CNOT7 ZMYND8 ZMYND8 DPF2 DPF2 SIRT6 SIRT6 ANKRD1 ANKRD1 BCL3 BCL3 MIER2 MIER2 BRD7 BRD7 SIRT7 SIRT7 TRIM28 TRIM28 YAF2 YAF2 LOC105506698 LOC105506698 ENSCANP00000038012 ENSCANP00000038012 CASP8AP2 CASP8AP2 PHF12 PHF12 RCOR2 RCOR2 LOC105506247 LOC105506247 SF1 SF1 AJUBA AJUBA ENSCANP00000036752 ENSCANP00000036752 CTBP2 CTBP2 ENSCANP00000036326 ENSCANP00000036326 TLE2 TLE2 LOC105516607 LOC105516607 ENSCANP00000035252 ENSCANP00000035252 ENSCANP00000035234 ENSCANP00000035234 PBXIP1 PBXIP1 RERE RERE DRAP1 DRAP1 TLE7 TLE7 SFMBT2 SFMBT2 PARP14 PARP14 CBFA2T2 CBFA2T2 SIAH2 SIAH2 MTA1 MTA1 ELMSAN1 ELMSAN1 RCOR3 RCOR3 LOC105502827 LOC105502827 CRYM CRYM TDP2 TDP2 YY1AP1 YY1AP1 SMARCA4 SMARCA4 LOC105515025 LOC105515025 GPS2 GPS2 CREBBP CREBBP HDAC1 HDAC1 ENSCANP00000030106 ENSCANP00000030106 WWTR1 WWTR1 JAZF1 JAZF1 NRIP1 NRIP1 TLE4 TLE4 SIN3B SIN3B NSD1 NSD1 CDYL2 CDYL2 PARP9 PARP9 SDR16C5 SDR16C5 DAXX DAXX PHB PHB HDAC9 HDAC9 PPP1R13L PPP1R13L FOXP3 FOXP3 ENSCANP00000027860 ENSCANP00000027860 LIMD1 LIMD1 TLE1 TLE1 DNMT3A DNMT3A SMYD1 SMYD1 SFMBT1 SFMBT1 ENSCANP00000027012 ENSCANP00000027012 WNT4 WNT4 MIER3 MIER3 NR0B1 NR0B1 ZMYND11 ZMYND11 TBL1XR1 TBL1XR1 DMAP1 DMAP1 RBFOX2 RBFOX2 C1QBP C1QBP HDGF HDGF FAM162B FAM162B TBL1X TBL1X BEND6 BEND6 TLE5 TLE5 N4BP2L2 N4BP2L2 CIR1 CIR1 ENSCANP00000022502 ENSCANP00000022502 ZNF366 ZNF366 SPEN SPEN BTG2 BTG2 NCOR2 NCOR2 TLE3 TLE3 NOC2L NOC2L SIN3A SIN3A LCOR LCOR RLIM RLIM RCOR1 RCOR1 RIOX2 RIOX2 CDYL CDYL FAM162A FAM162A MTA3 MTA3 CCND1 CCND1 ZNF653 ZNF653 ELANE ELANE CITED2 CITED2 TLE6 TLE6 NAB2 NAB2 ZFPM2 ZFPM2 TCP10L TCP10L MLIP MLIP PARP15 PARP15 MED1 MED1 TRIM22 TRIM22 LOC105515027 LOC105515027 BCOR BCOR LMCD1 LMCD1 LOC105512634 LOC105512634 NCOA5 NCOA5 UXT UXT ATN1 ATN1 EZH2 EZH2 NCOR1 NCOR1 ZNF451 ZNF451 CREG1 CREG1 TRIB3 TRIB3 HMGA2 HMGA2 ARID5A ARID5A GON4L GON4L YAP1 YAP1 PEX14 PEX14 HDAC3 HDAC3 SNW1 SNW1 SUFU SUFU TCF25 TCF25 TRERF1 TRERF1 MYBBP1A MYBBP1A TCERG1 TCERG1 HDAC7 HDAC7 ATF7IP ATF7IP LOC105527037 LOC105527037 HSBP1 HSBP1 RYBP RYBP ENSCANP00000003880 ENSCANP00000003880 LOC105526098 LOC105526098 LOC105516014 LOC105516014 IRF2BP1 IRF2BP1 RBBP8 RBBP8 IRF2BP2 IRF2BP2 PRKN PRKN ENSCANP00000005082 ENSCANP00000005082 ENSCANP00000005253 ENSCANP00000005253 URI1 URI1 DDX54 DDX54 PA2G4 PA2G4 BCORL1 BCORL1 HNRNPU HNRNPU KMT5A KMT5A RUVBL2 RUVBL2 FHL2 FHL2 SIRT1 SIRT1 DNMT3B DNMT3B CTBP1 CTBP1 NR0B2 NR0B2 SAP18 SAP18 HIPK2 HIPK2 ENSCANP00000010400 ENSCANP00000010400 CCAR1 CCAR1 MECP2 MECP2 ENSCANP00000010884 ENSCANP00000010884 KDM5B KDM5B PIAS4 PIAS4 NPAT NPAT RUNX1T1 RUNX1T1 COPS2 COPS2 TFAP2A TFAP2A LOC105516286 LOC105516286 LOC105515026 LOC105515026 SSX1 SSX1 TSG101 TSG101 DNAJB1 DNAJB1 ENSCANP00000012462 ENSCANP00000012462 IRF2BPL IRF2BPL AASS AASS GMNN GMNN HSBP1L1 HSBP1L1 ENSCANP00000013332 ENSCANP00000013332 LOC105524802 LOC105524802 PRMT5 PRMT5 CBFA2T3 CBFA2T3 HIRA HIRA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC105515029KRAB-related domain-containing protein. (215 aa)
MAP3K10Mitogen-activated protein kinase kinase kinase 10. (777 aa)
MTA2Metastasis associated 1 family member 2. (673 aa)
PIAS1Protein inhibitor of activated STAT 1. (653 aa)
PARP10Poly [ADP-ribose] polymerase. (1026 aa)
CBX4Chromobox 4. (613 aa)
SCAIProtein SCAI; Tumor suppressor which functions to suppress MRTFA-induced SRF transcriptional activity. (620 aa)
CNOT7CCR4-NOT transcription complex subunit 7. (285 aa)
ZMYND8Zinc finger MYND-type containing 8. (1241 aa)
DPF2Double PHD fingers 2. (405 aa)
SIRT6Sirtuin 6. (355 aa)
ANKRD1Ankyrin repeat domain 1. (319 aa)
BCL3BCL3 transcription coactivator. (381 aa)
MIER2MIER family member 2. (544 aa)
BRD7Bromodomain containing 7. (642 aa)
SIRT7Sirtuin 7. (361 aa)
TRIM28Tripartite motif containing 28. (823 aa)
YAF2YY1 associated factor 2. (204 aa)
LOC105506698Uncharacterized protein. (354 aa)
ENSCANP00000038012Prohibitin. (190 aa)
CASP8AP2Caspase 8 associated protein 2. (1985 aa)
PHF12PHD finger protein 12. (1004 aa)
RCOR2REST corepressor 2. (523 aa)
LOC105506247Uncharacterized protein. (92 aa)
SF1Splicing factor 1. (639 aa)
AJUBAAjuba LIM protein. (538 aa)
ENSCANP00000036752Uncharacterized protein. (90 aa)
CTBP2C-terminal binding protein 2. (985 aa)
ENSCANP00000036326Uncharacterized protein. (144 aa)
TLE2TLE family member 2, transcriptional corepressor. (653 aa)
LOC105516607Peptidase_M24 domain-containing protein. (337 aa)
ENSCANP00000035252Uncharacterized protein. (319 aa)
ENSCANP00000035234Prohibitin. (260 aa)
PBXIP1PBX homeobox interacting protein 1. (736 aa)
REREArginine-glutamic acid dipeptide repeats. (1484 aa)
DRAP1DR1 associated protein 1. (191 aa)
TLE7TLE family member 7. (440 aa)
SFMBT2Scm like with four mbt domains 2. (894 aa)
PARP14Poly [ADP-ribose] polymerase. (1800 aa)
CBFA2T2CBFA2/RUNX1 partner transcriptional co-repressor 2. (584 aa)
SIAH2E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. (299 aa)
MTA1Metastasis associated 1. (712 aa)
ELMSAN1ELM2 and Myb/SANT domain containing 1. (1100 aa)
RCOR3REST corepressor 3. (455 aa)
LOC105502827Prohibitin. (244 aa)
CRYMCrystallin mu. (314 aa)
TDP2Tyrosyl-DNA phosphodiesterase 2. (358 aa)
YY1AP1YY1 associated protein 1. (875 aa)
SMARCA4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4. (1686 aa)
LOC105515025KRAB-related domain-containing protein. (217 aa)
GPS2G protein pathway suppressor 2. (327 aa)
CREBBPCREB binding protein. (2117 aa)
HDAC1Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (476 aa)
ENSCANP00000030106KRAB-related domain-containing protein. (195 aa)
WWTR1WW domain containing transcription regulator 1. (400 aa)
JAZF1JAZF zinc finger 1. (243 aa)
NRIP1Nuclear receptor interacting protein 1. (1155 aa)
TLE4TLE family member 4, transcriptional corepressor. (790 aa)
SIN3BSIN3 transcription regulator family member B. (1158 aa)
NSD1Nuclear receptor binding SET domain protein 1. (2682 aa)
CDYL2Chromodomain Y like 2. (504 aa)
PARP9Poly(ADP-ribose) polymerase family member 9. (818 aa)
SDR16C5Short chain dehydrogenase/reductase family 16C member 5; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (309 aa)
DAXXDeath domain associated protein. (751 aa)
PHBProhibitin. (272 aa)
HDAC9Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1066 aa)
PPP1R13LProtein phosphatase 1 regulatory subunit 13 like. (782 aa)
FOXP3Forkhead box P3. (441 aa)
ENSCANP00000027860KRAB-related domain-containing protein. (206 aa)
LIMD1LIM domains containing 1. (677 aa)
TLE1TLE family member 1, transcriptional corepressor. (770 aa)
DNMT3ADNA methyltransferase 3 alpha; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (912 aa)
SMYD1SET and MYND domain containing 1. (497 aa)
SFMBT1Scm like with four mbt domains 1. (866 aa)
ENSCANP00000027012Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (435 aa)
WNT4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (345 aa)
MIER3MIER family member 3. (552 aa)
NR0B1Nuclear receptor subfamily 0 group B member 1. (470 aa)
ZMYND11Zinc finger MYND-type containing 11. (635 aa)
TBL1XR1Transducin beta like 1 X-linked receptor 1. (514 aa)
DMAP1DNA methyltransferase 1 associated protein 1. (467 aa)
RBFOX2RNA binding protein fox-1 homolog 2; RNA-binding protein that regulates alternative splicing events. (389 aa)
C1QBPComplement C1q binding protein. (280 aa)
HDGFUncharacterized protein. (211 aa)
FAM162BFamily with sequence similarity 162 member B. (142 aa)
TBL1XTransducin beta like 1 X-linked. (575 aa)
BEND6BEN domain containing 6. (277 aa)
TLE5TLE family member 5, transcriptional modulator. (191 aa)
N4BP2L2NEDD4 binding protein 2 like 2. (751 aa)
CIR1Corepressor interacting with RBPJ, 1. (443 aa)
ENSCANP00000022502Prohibitin. (185 aa)
ZNF366Zinc finger protein 366. (745 aa)
SPENSpen family transcriptional repressor. (3641 aa)
BTG2BTG anti-proliferation factor 2. (158 aa)
NCOR2Nuclear receptor corepressor 2. (2510 aa)
TLE3TLE family member 3, transcriptional corepressor. (782 aa)
NOC2LNOC2 like nucleolar associated transcriptional repressor. (679 aa)
SIN3ASIN3 transcription regulator family member A. (1273 aa)
LCORLigand dependent nuclear receptor corepressor. (1556 aa)
RLIMRing finger protein, LIM domain interacting. (620 aa)
RCOR1REST corepressor 1. (480 aa)
RIOX2Bifunctional lysine-specific demethylase and histidyl-hydroxylase; Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase. (465 aa)
CDYLChromodomain Y like. (604 aa)
FAM162AFamily with sequence similarity 162 member A. (155 aa)
MTA3Metastasis associated 1 family member 3. (591 aa)
CCND1Cyclin D1; Belongs to the cyclin family. (295 aa)
ZNF653Uncharacterized protein. (306 aa)
ELANEElastase, neutrophil expressed; Belongs to the peptidase S1 family. (265 aa)
CITED2Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2. (278 aa)
TLE6WD_REPEATS_REGION domain-containing protein. (299 aa)
NAB2NGFI-A binding protein 2. (525 aa)
ZFPM2Zinc finger protein, FOG family member 2. (1137 aa)
TCP10LT-complex 10 like. (213 aa)
MLIPMuscular LMNA interacting protein. (992 aa)
PARP15Poly [ADP-ribose] polymerase. (663 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1576 aa)
TRIM22Tripartite motif containing 22. (498 aa)
LOC105515027KRAB-related domain-containing protein. (109 aa)
BCORBCL6 corepressor. (1755 aa)
LMCD1LIM and cysteine rich domains 1. (365 aa)
LOC105512634Uncharacterized protein. (231 aa)
NCOA5Nuclear receptor coactivator 5. (584 aa)
UXTUbiquitously expressed prefoldin like chaperone. (157 aa)
ATN1Atrophin 1. (1180 aa)
EZH2Enhancer of zeste 2 polycomb repressive complex 2 subunit. (746 aa)
NCOR1Nuclear receptor corepressor 1. (2440 aa)
ZNF451Zinc finger protein 451. (1061 aa)
CREG1Cellular repressor of E1A stimulated genes 1. (152 aa)
TRIB3Tribbles pseudokinase 3. (385 aa)
HMGA2High mobility group AT-hook 2. (147 aa)
ARID5AAT-rich interaction domain 5A. (592 aa)
GON4LGon-4 like. (2112 aa)
YAP1Yes associated protein 1. (479 aa)
PEX14Peroxisomal biogenesis factor 14. (377 aa)
HDAC3Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (428 aa)
SNW1SNW domain containing 1. (571 aa)
SUFUSuppressor of fused homolog; Negative regulator in the hedgehog signaling pathway. Down- regulates GLI1-mediated transactivation of target genes. Part of a corepressor complex that acts on DNA-bound GLI1. May also act by linking GLI1 to BTRC and thereby targeting GLI1 to degradation by the proteasome. Sequesters GLI1, GLI2 and GLI3 in the cytoplasm, this effect is overcome by binding of STK36 to both SUFU and a GLI protein. Negative regulator of beta-catenin signaling. Regulates the formation of either the repressor form (GLI3R) or the activator form (GLI3A) of the full-length form of [...] (519 aa)
TCF25Transcription factor 25. (676 aa)
TRERF1Transcriptional regulating factor 1. (1216 aa)
MYBBP1AMYB binding protein 1a. (1226 aa)
TCERG1Transcription elongation regulator 1. (1094 aa)
HDAC7Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1002 aa)
ATF7IPActivating transcription factor 7 interacting protein. (1277 aa)
LOC105527037Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (459 aa)
HSBP1Heat shock factor binding protein 1. (76 aa)
RYBPRING1 and YY1 binding protein. (230 aa)
ENSCANP00000003880Hist_deacetyl domain-containing protein. (281 aa)
LOC105526098SET domain-containing protein. (333 aa)
LOC105516014Peptidase_M24 domain-containing protein. (324 aa)
IRF2BP1Interferon regulatory factor 2 binding protein 1. (584 aa)
RBBP8RB binding protein 8, endonuclease. (898 aa)
IRF2BP2Interferon regulatory factor 2 binding protein 2. (317 aa)
PRKNE3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. (465 aa)
ENSCANP00000005082Uncharacterized protein. (45 aa)
ENSCANP00000005253Uncharacterized protein. (76 aa)
URI1Uncharacterized protein. (497 aa)
DDX54ATP-dependent RNA helicase DDX54; Belongs to the DEAD box helicase family. DDX54/DBP10 subfamily. (760 aa)
PA2G4Peptidase_M24 domain-containing protein. (394 aa)
BCORL1BCL6 corepressor like 1. (1711 aa)
HNRNPUHeterogeneous nuclear ribonucleoprotein U. (821 aa)
KMT5ASET domain-containing protein. (326 aa)
RUVBL2RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (466 aa)
FHL2Four and a half LIM domains 2. (363 aa)
SIRT1Sirtuin 1. (600 aa)
DNMT3BDNA methyltransferase 3 beta; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (853 aa)
CTBP1C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (442 aa)
NR0B2Nuclear receptor subfamily 0 group B member 2. (257 aa)
SAP18Sin3A associated protein 18. (172 aa)
HIPK2Homeodomain interacting protein kinase 2. (1197 aa)
ENSCANP00000010400Uncharacterized protein. (486 aa)
CCAR1DBC1 domain-containing protein. (568 aa)
MECP2Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC). (498 aa)
ENSCANP00000010884Uncharacterized protein. (338 aa)
KDM5BLysine demethylase 5B. (1487 aa)
PIAS4Protein inhibitor of activated STAT 4. (510 aa)
NPATNuclear protein, coactivator of histone transcription. (1428 aa)
RUNX1T1RUNX1 partner transcriptional co-repressor 1. (662 aa)
COPS2COP9 signalosome subunit 2. (450 aa)
TFAP2ATranscription factor AP-2 alpha. (439 aa)
LOC105516286Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (449 aa)
LOC105515026KRAB-related domain-containing protein. (188 aa)
SSX1SSX family member 1. (188 aa)
TSG101Tumor susceptibility 101. (390 aa)
DNAJB1DnaJ heat shock protein family (Hsp40) member B1. (340 aa)
ENSCANP00000012462KRAB-related domain-containing protein. (198 aa)
IRF2BPLInterferon regulatory factor 2 binding protein like. (625 aa)
AASSAminoadipate-semialdehyde synthase. (851 aa)
GMNNGeminin DNA replication inhibitor. (209 aa)
HSBP1L1Heat shock factor binding protein 1 like 1. (54 aa)
ENSCANP00000013332Uncharacterized protein. (144 aa)
LOC105524802Bromo domain-containing protein. (585 aa)
PRMT5Protein arginine N-methyltransferase 5; Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA); Belongs to the class I-like SAM-binding methyltransferase superfamily. (620 aa)
CBFA2T3CBFA2/RUNX1 partner transcriptional co-repressor 3. (586 aa)
HIRAProtein HIRA; Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle; Belongs to the WD repeat HIR1 family. (1017 aa)
Your Current Organism:
Colobus angolensis
NCBI taxonomy Id: 336983
Other names: C. angolensis palliatus, Colobus angolensis palliatus
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