STRINGSTRING
IL23A IL23A IL34 IL34 WNT7A WNT7A ENSCANP00000018729 ENSCANP00000018729 WNT8B WNT8B IL24 IL24 TNFRSF11B TNFRSF11B CCL3L3 CCL3L3 WNT2 WNT2 CCL19 CCL19 LTA LTA SCGB3A1 SCGB3A1 BMP15 BMP15 CCL17 CCL17 IL27 IL27 MSTN MSTN IL36G IL36G GDF2 GDF2 TIMP1 TIMP1 LOC105501296 LOC105501296 SPP1 SPP1 IFNG IFNG WNT8A WNT8A TNFSF11 TNFSF11 WNT10B WNT10B GDF6 GDF6 BMP4 BMP4 IL17C IL17C GDF7 GDF7 THPO THPO GPI GPI BMP2 BMP2 LOC105501293 LOC105501293 CMTM7 CMTM7 CSF1 CSF1 CSF2 CSF2 WNT11 WNT11 CX3CL1 CX3CL1 IL3 IL3 TSLP TSLP CXCL6 CXCL6 GDF9 GDF9 WNT3 WNT3 ENSCANP00000010409 ENSCANP00000010409 OSM OSM IL19 IL19 LOC105505555 LOC105505555 WNT1 WNT1 BMP6 BMP6 ALKAL2 ALKAL2 TGFB1 TGFB1 CMTM5 CMTM5 FASLG FASLG BMP5 BMP5 ENSCANP00000006994 ENSCANP00000006994 CMTM8 CMTM8 CCL4 CCL4 CCL2 CCL2 GDF10 GDF10 TNFSF18 TNFSF18 C5 C5 IL16 IL16 INHBA INHBA LOC105521177 LOC105521177 LOC105505556 LOC105505556 TNFSF10 TNFSF10 ALKAL1 ALKAL1 GREM2 GREM2 WNT7B WNT7B MIF MIF C10orf99 C10orf99 CCL20 CCL20 GDF11 GDF11 LOC105524214 LOC105524214 LIF LIF CCL23 CCL23 ENSCANP00000002034 ENSCANP00000002034 WNT9B WNT9B ENSCANP00000001394 ENSCANP00000001394 WNT10A WNT10A TNFSF4 TNFSF4 IL20 IL20 LOC105503436 LOC105503436 EDN1 EDN1 PPBP PPBP IL18 IL18 IL17F IL17F TGFB2 TGFB2 MSMP MSMP KITLG KITLG WNT6 WNT6 CXCL13 CXCL13 IL7 IL7 CCL7 CCL7 TNF TNF CXCL10 CXCL10 CCL27 CCL27 IL4 IL4 IL13 IL13 BMP7 BMP7 CXCL14 CXCL14 CCL21 CCL21 CXCL17 CXCL17 BMP3 BMP3 CXCL2 CXCL2 FAM3B FAM3B IL2 IL2 GDF5 GDF5 CXCL1 CXCL1 CMTM3 CMTM3 NAMPT NAMPT GDF15 GDF15 CMTM1 CMTM1 CNTF CNTF CER1 CER1 ADIPOQ ADIPOQ CCL13 CCL13 NTN1 NTN1 WNT4 WNT4 IL21 IL21 AIMP1 AIMP1 CCL1 CCL1 CRLF1 CRLF1 IL17B IL17B NRG1 NRG1 CMTM2 CMTM2 LOC105516701 LOC105516701 TNFSF13 TNFSF13 WNT3A WNT3A WNT9A WNT9A VSTM1 VSTM1 IFNB1 IFNB1 CXCL8 CXCL8 BMP10 BMP10 CTF1 CTF1 CCL28 CCL28 INHBE INHBE CSF3 CSF3 INHA INHA LTB LTB IL26 IL26 CXCL16 CXCL16 BMP8B BMP8B TNFSF12 TNFSF12 IL1B IL1B ENSCANP00000031396 ENSCANP00000031396 GDF3 GDF3 EPO EPO CCL22 CCL22 TNFSF15 TNFSF15 TGFB3 TGFB3 IL22 IL22 GRN GRN CCL26 CCL26 TNFSF14 TNFSF14 WNT5A WNT5A IL36A IL36A IL5 IL5 IFNL1 IFNL1 IL36RN IL36RN WNT2B WNT2B IL12B IL12B LOC105516700 LOC105516700 CD40LG CD40LG IL17A IL17A NODAL NODAL IL9 IL9 IL36B IL36B CXCL11 CXCL11 C17orf99 C17orf99 IL1F10 IL1F10 IL1A IL1A WNT16 WNT16 NDP NDP CCL5 CCL5 CCL14 CCL14 SLURP1 SLURP1 LOC105518758 LOC105518758 CCL16 CCL16 CCL11 CCL11 IL37 IL37 IL1RN IL1RN CCL8 CCL8 TNFSF9 TNFSF9 PF4V1 PF4V1 IL15 IL15 IL10 IL10 IL12A IL12A CXCL12 CXCL12 TNFSF8 TNFSF8 CCL3 CCL3 FLT3LG FLT3LG CCL18 CCL18 ENSCANP00000037537 ENSCANP00000037537 IFNE IFNE IL6 IL6 IL31 IL31 AREG AREG LOC105501292 LOC105501292 IL25 IL25 SECTM1 SECTM1 CCL24 CCL24 TNFSF13B TNFSF13B CXCL9 CXCL9 BMP1 BMP1 IL11 IL11 INHBC INHBC PF4 PF4 LOC105519149 LOC105519149 CLCF1 CLCF1 IL33 IL33
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
IL23AInterleukin 23 subunit alpha. (200 aa)
IL34Interleukin 34. (242 aa)
WNT7AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (349 aa)
ENSCANP00000018729Uncharacterized protein. (108 aa)
WNT8BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa)
IL24Interleukin 24. (207 aa)
TNFRSF11BTNF receptor superfamily member 11b. (428 aa)
CCL3L3C-C motif chemokine. (93 aa)
WNT2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (360 aa)
CCL19C-C motif chemokine. (104 aa)
LTALymphotoxin alpha; Belongs to the tumor necrosis factor family. (205 aa)
SCGB3A1Secretoglobin family 3A member 1. (102 aa)
BMP15Bone morphogenetic protein 15. (393 aa)
CCL17C-C motif chemokine. (93 aa)
IL27Interleukin 27. (242 aa)
MSTNMyostatin. (376 aa)
IL36GInterleukin-1. (169 aa)
GDF2Growth differentiation factor 2. (429 aa)
TIMP1TIMP metallopeptidase inhibitor 1. (207 aa)
LOC105501296C-X-C motif chemokine. (114 aa)
SPP1Secreted phosphoprotein 1. (314 aa)
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (165 aa)
WNT8AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa)
TNFSF11TNF superfamily member 11; Belongs to the tumor necrosis factor family. (317 aa)
WNT10BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa)
GDF6Growth differentiation factor 6. (455 aa)
BMP4Bone morphogenetic protein 4. (408 aa)
IL17CInterleukin 17C. (197 aa)
GDF7Growth differentiation factor 7. (366 aa)
THPOThrombopoietin. (308 aa)
GPIGlucose-6-phosphate isomerase; Belongs to the GPI family. (530 aa)
BMP2Bone morphogenetic protein 2. (396 aa)
LOC105501293C-X-C motif chemokine. (107 aa)
CMTM7CKLF like MARVEL transmembrane domain containing 7. (158 aa)
CSF1Macrophage colony-stimulating factor 1; Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female [...] (551 aa)
CSF2Colony stimulating factor 2. (144 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (330 aa)
CX3CL1C-X3-C motif chemokine ligand 1. (402 aa)
IL3Interleukin-3; Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. Belongs to the IL-3 family. (143 aa)
TSLPThymic stromal lymphopoietin. (159 aa)
CXCL6C-X-C motif chemokine. (114 aa)
GDF9Growth differentiation factor 9. (366 aa)
WNT3Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa)
ENSCANP00000010409Uncharacterized protein. (203 aa)
OSMOncostatin M. (252 aa)
IL19Interleukin 19. (177 aa)
LOC105505555SCY domain-containing protein. (114 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
BMP6Bone morphogenetic protein 6. (331 aa)
ALKAL2Uncharacterized protein. (75 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (336 aa)
CMTM5CKLF like MARVEL transmembrane domain containing 5. (222 aa)
FASLGFas ligand; Belongs to the tumor necrosis factor family. (280 aa)
BMP5Bone morphogenetic protein 5. (454 aa)
ENSCANP00000006994Uncharacterized protein. (184 aa)
CMTM8CKLF like MARVEL transmembrane domain containing 8. (173 aa)
CCL4C-C motif chemokine. (92 aa)
CCL2C-C motif chemokine. (99 aa)
GDF10Bone morphogenetic protein 3; Belongs to the TGF-beta family. (474 aa)
TNFSF18TNF superfamily member 18. (199 aa)
C5Complement C5. (1663 aa)
IL16Pro-interleukin-16; Interleukin-16 stimulates a migratory response in CD4+ lymphocytes, monocytes, and eosinophils. Primes CD4+ T-cells for IL-2 and IL-15 responsiveness. Also induces T-lymphocyte expression of interleukin 2 receptor. Ligand for CD4. (1332 aa)
INHBAInhibin subunit beta A. (426 aa)
LOC105521177TGF_BETA_2 domain-containing protein. (238 aa)
LOC105505556SCY domain-containing protein. (114 aa)
TNFSF10Tumor necrosis factor ligand superfamily member. (281 aa)
ALKAL1ALK and LTK ligand 1. (111 aa)
GREM2Gremlin. (168 aa)
WNT7BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa)
MIFUncharacterized protein. (114 aa)
C10orf99Chromosome 10 open reading frame 99. (81 aa)
CCL20C-C motif chemokine. (96 aa)
GDF11Growth differentiation factor 11. (345 aa)
LOC105524214Uncharacterized protein. (65 aa)
LIFLIF interleukin 6 family cytokine. (204 aa)
CCL23C-C motif chemokine. (117 aa)
ENSCANP00000002034Uncharacterized protein. (114 aa)
WNT9BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (350 aa)
ENSCANP00000001394Glucose-6-phosphate isomerase; Belongs to the GPI family. (504 aa)
WNT10AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (417 aa)
TNFSF4TNF superfamily member 4; Belongs to the tumor necrosis factor family. (183 aa)
IL20Interleukin 20. (176 aa)
LOC105503436Uncharacterized protein. (198 aa)
EDN1Endothelin 1. (211 aa)
PPBPC-X-C motif chemokine. (128 aa)
IL18Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family. (193 aa)
IL17FInterleukin 17F. (163 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
MSMPBeta-microseminoprotein. (139 aa)
KITLGKit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. Belongs to the SCF family. (273 aa)
WNT6Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (358 aa)
CXCL13C-X-C motif chemokine. (109 aa)
IL7Interleukin 7. (178 aa)
CCL7C-C motif chemokine ligand 7. (99 aa)
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa)
CXCL10C-X-C motif chemokine. (98 aa)
CCL27C-C motif chemokine ligand 27. (112 aa)
IL4Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Belongs to the IL-4/IL-13 family. (153 aa)
IL13Interleukin 13. (146 aa)
BMP7Bone morphogenetic protein 7. (431 aa)
CXCL14C-X-C motif chemokine ligand 14. (111 aa)
CCL21C-C motif chemokine ligand 21. (131 aa)
CXCL17C-X-C motif chemokine ligand 17. (119 aa)
BMP3Bone morphogenetic protein 3; Belongs to the TGF-beta family. (472 aa)
CXCL2C-X-C motif chemokine. (107 aa)
FAM3BFamily with sequence similarity 3 member B. (249 aa)
IL2Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family. (154 aa)
GDF5Growth differentiation factor 5. (499 aa)
CXCL1C-X-C motif chemokine. (107 aa)
CMTM3CKLF like MARVEL transmembrane domain containing 3. (163 aa)
NAMPTNicotinamide phosphoribosyltransferase; Belongs to the NAPRTase family. (486 aa)
GDF15Growth differentiation factor 15. (308 aa)
CMTM1CKLF like MARVEL transmembrane domain containing 1. (286 aa)
CNTFCiliary neurotrophic factor. (200 aa)
CER1Cerberus 1, DAN family BMP antagonist. (267 aa)
ADIPOQAdiponectin, C1Q and collagen domain containing. (244 aa)
CCL13C-C motif chemokine. (98 aa)
NTN1Netrin 1. (576 aa)
WNT4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (345 aa)
IL21Interleukin; Belongs to the IL-15/IL-21 family. (162 aa)
AIMP1Aminoacyl tRNA synthetase complex interacting multifunctional protein 1. (321 aa)
CCL1C-C motif chemokine. (96 aa)
CRLF1Cytokine receptor like factor 1. (377 aa)
IL17BInterleukin 17B. (180 aa)
NRG1Neuregulin 1. (645 aa)
CMTM2CKLF like MARVEL transmembrane domain containing 2. (226 aa)
LOC105516701TGF_BETA_2 domain-containing protein. (283 aa)
TNFSF13TNF superfamily member 13; Belongs to the tumor necrosis factor family. (250 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
WNT9AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
VSTM1Ig-like domain-containing protein. (143 aa)
IFNB1Interferon beta 1. (187 aa)
CXCL8Multifunctional fusion protein; Belongs to the intercrine alpha (chemokine CxC) family. (101 aa)
BMP10Bone morphogenetic protein 10. (424 aa)
CTF1Uncharacterized protein. (202 aa)
CCL28C-C motif chemokine. (127 aa)
INHBEInhibin subunit beta E. (351 aa)
CSF3Colony stimulating factor 3. (207 aa)
INHAInhibin alpha chain; Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition; Belongs to the TGF-beta family. (366 aa)
LTBLymphotoxin beta; Belongs to the tumor necrosis factor family. (204 aa)
IL26Interleukin 26. (171 aa)
CXCL16C-X-C motif chemokine ligand 16. (275 aa)
BMP8BTGF_BETA_2 domain-containing protein. (336 aa)
TNFSF12TNF superfamily member 12; Belongs to the tumor necrosis factor family. (220 aa)
IL1BMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (269 aa)
ENSCANP00000031396TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (167 aa)
GDF3Growth differentiation factor 3. (364 aa)
EPOErythropoietin; Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. Belongs to the EPO/TPO family. (192 aa)
CCL22C-C motif chemokine. (93 aa)
TNFSF15TNF superfamily member 15. (251 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
IL22Interleukin 22. (179 aa)
GRNGranulin precursor. (593 aa)
CCL26C-C motif chemokine. (94 aa)
TNFSF14TNF superfamily member 14; Belongs to the tumor necrosis factor family. (240 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
IL36AInterleukin-1. (158 aa)
IL5Interleukin-5; Factor that induces terminal differentiation of late- developing B-cells to immunoglobulin secreting cells. (134 aa)
IFNL1Interferon lambda 1. (202 aa)
IL36RNInterleukin-1. (155 aa)
WNT2BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (391 aa)
IL12BInterleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. (328 aa)
LOC105516700TGF_BETA_2 domain-containing protein. (311 aa)
CD40LGCD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching. (261 aa)
IL17AInterleukin 17A. (155 aa)
NODALNodal growth differentiation factor. (347 aa)
IL9Interleukin 9. (145 aa)
IL36BInterleukin 36 beta. (162 aa)
CXCL11C-X-C motif chemokine. (94 aa)
C17orf99Chromosome 17 open reading frame 99. (265 aa)
IL1F10Interleukin-1. (152 aa)
IL1AInterleukin-1; Belongs to the IL-1 family. (271 aa)
WNT16Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa)
NDPNorrin cystine knot growth factor NDP. (133 aa)
CCL5C-C motif chemokine. (91 aa)
CCL14C-C motif chemokine. (114 aa)
SLURP1Secreted LY6/PLAUR domain containing 1. (103 aa)
LOC105518758C-C motif chemokine. (111 aa)
CCL16C-C motif chemokine. (122 aa)
CCL11C-C motif chemokine. (97 aa)
IL37Interleukin-1. (218 aa)
IL1RNInterleukin-1. (159 aa)
CCL8C-C motif chemokine. (99 aa)
TNFSF9TNF superfamily member 9; Belongs to the tumor necrosis factor family. (211 aa)
PF4V1C-X-C motif chemokine. (101 aa)
IL15Interleukin; Belongs to the IL-15/IL-21 family. (162 aa)
IL10Interleukin 10. (178 aa)
IL12AInterleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC. (253 aa)
CXCL12C-X-C motif chemokine ligand 12; Belongs to the intercrine alpha (chemokine CxC) family. (140 aa)
TNFSF8TNF superfamily member 8; Belongs to the tumor necrosis factor family. (234 aa)
CCL3C-C motif chemokine. (92 aa)
FLT3LGFms related tyrosine kinase 3 ligand. (236 aa)
CCL18C-C motif chemokine. (78 aa)
ENSCANP00000037537C1q domain-containing protein. (100 aa)
IFNEInterferon epsilon. (196 aa)
IL6Interleukin 6. (214 aa)
IL31Interleukin 31. (163 aa)
AREGAmphiregulin. (275 aa)
LOC105501292C-X-C motif chemokine. (112 aa)
IL25Interleukin 25. (177 aa)
SECTM1Secreted and transmembrane 1. (242 aa)
CCL24C-C motif chemokine ligand 24. (119 aa)
TNFSF13BTNF superfamily member 13b; Belongs to the tumor necrosis factor family. (285 aa)
CXCL9C-X-C motif chemokine ligand 9. (125 aa)
BMP1Metalloendopeptidase. (980 aa)
IL11Interleukin 11. (199 aa)
INHBCInhibin subunit beta C. (352 aa)
PF4C-X-C motif chemokine. (101 aa)
LOC105519149Uncharacterized protein. (200 aa)
CLCF1Cardiotrophin like cytokine factor 1. (223 aa)
IL33Interleukin 33. (270 aa)
Your Current Organism:
Colobus angolensis
NCBI taxonomy Id: 336983
Other names: C. angolensis palliatus, Colobus angolensis palliatus
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