81 items (Colobus angolensis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DNAJA3	DnaJ heat shock protein family (Hsp40) member A3. (480 aa)
	NLRC4	NLR family CARD domain containing 4. (1024 aa)
	APAF1	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. (1248 aa)
	VCP	Valosin containing protein; Belongs to the AAA ATPase family. (804 aa)
	ENSCANP00000039262	Uncharacterized protein; Belongs to the GroES chaperonin family. (87 aa)
	LCK	Tyrosine-protein kinase. (539 aa)
	CASP8AP2	Caspase 8 associated protein 2. (1985 aa)
	HIP1	Huntingtin interacting protein 1. (1037 aa)
	HSPE1	10 kDa heat shock protein, mitochondrial. (102 aa)
	NLRP3	NLR family pyrin domain containing 3. (1035 aa)
	SLC1A1	Amino acid transporter. (524 aa)
	CASP2	Caspase 2; Belongs to the peptidase C14A family. (404 aa)
	BCL2L10	Uncharacterized protein. (204 aa)
	AIFM1	Apoptosis inducing factor mitochondria associated 1. (565 aa)
	F2R	Coagulation factor II thrombin receptor; Belongs to the G-protein coupled receptor 1 family. (413 aa)
	JAK2	Tyrosine-protein kinase. (1139 aa)
	CRADD	CASP2 and RIPK1 domain containing adaptor with death domain. (199 aa)
	S100A8	Protein S100; Belongs to the S-100 family. (92 aa)
	EGLN3	Egl-9 family hypoxia inducible factor 3. (239 aa)
	TNFSF15	TNF superfamily member 15. (251 aa)
	DIABLO	Uncharacterized protein. (239 aa)
	ENSCANP00000031005	Uncharacterized protein. (101 aa)
	IFT57	Intraflagellar transport 57. (428 aa)
	LOC105500957	Uncharacterized protein; Belongs to the peptidase C14A family. (406 aa)
	HIP1R	Huntingtin interacting protein 1 related. (1062 aa)
	BAX	BCL2 associated X, apoptosis regulator. (198 aa)
	ANP32B	Acidic nuclear phosphoprotein 32 family member B. (251 aa)
	MTCH1	Mitochondrial carrier 1; Belongs to the mitochondrial carrier (TC 2.A.29) family. (343 aa)
	CASP10	Caspase 10; Belongs to the peptidase C14A family. (484 aa)
	BID	BH3 interacting domain death agonist. (255 aa)
	KHDC1L	KH domain containing 1 like. (128 aa)
	XDH	Xanthine dehydrogenase. (1333 aa)
	CTSH	Cathepsin H; Belongs to the peptidase C1 family. (331 aa)
	CASP1	Caspase 1; Belongs to the peptidase C14A family. (372 aa)
	PIDD1	P53-induced death domain protein 1. (910 aa)
	EIF2AK3	Eukaryotic translation initiation factor 2 alpha kinase 3. (965 aa)
	NLRP1	NLR family pyrin domain containing 1. (1419 aa)
	BAK1	BCL2 antagonist/killer 1. (211 aa)
	NLRP12	NLR family pyrin domain containing 12. (1033 aa)
	FAM162A	Family with sequence similarity 162 member A. (155 aa)
	BCL2L13	BCL2 like 13. (493 aa)
	ATP2A3	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1060 aa)
	COL4A3	Collagen type IV alpha 3 chain. (1646 aa)
	ROBO1	Roundabout guidance receptor 1. (1598 aa)
	NGFR	Nerve growth factor receptor. (427 aa)
	RACK1	WD_REPEATS_REGION domain-containing protein. (241 aa)
	PYCARD	PYD and CARD domain containing. (195 aa)
	LOC105513574	MOEP19 domain-containing protein. (162 aa)
	PDCD2	Programmed cell death 2. (257 aa)
	ENSCANP00000015194	Uncharacterized protein; Belongs to the GroES chaperonin family. (93 aa)
	SLC11A2	Solute carrier family 11 member 2. (568 aa)
	LOC105505011	WD_REPEATS_REGION domain-containing protein. (312 aa)
	LAPTM5	Lysosomal protein transmembrane 5. (262 aa)
	CASP8	Caspase 8; Belongs to the peptidase C14A family. (538 aa)
	ACER2	Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (275 aa)
	BOK	BCL2 family apoptosis regulator BOK. (171 aa)
	MUL1	Mitochondrial E3 ubiquitin protein ligase 1. (352 aa)
	KHDC1	MOEP19 domain-containing protein. (164 aa)
	NKX3-1	NK3 homeobox 1. (232 aa)
	P2RX1	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (375 aa)
	NOD1	Nucleotide binding oligomerization domain containing 1. (953 aa)
	BCL2L11	Bcl-2-like protein 11; Induces apoptosis and anoikis. Belongs to the Bcl-2 family. (198 aa)
	ST20	Uncharacterized protein. (71 aa)
	CASP9	Caspase 9; Belongs to the peptidase C14A family. (416 aa)
	RET	Proto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands. (1089 aa)
	DLC1	DLC1 Rho GTPase activating protein. (1528 aa)
	FASLG	Fas ligand; Belongs to the tumor necrosis factor family. (280 aa)
	PML	Promyelocytic leukemia. (882 aa)
	LOC105500754	10 kDa heat shock protein, mitochondrial. (102 aa)
	ENSCANP00000005277	Uncharacterized protein; Belongs to the GroES chaperonin family. (102 aa)
	BAD	BCL2 associated agonist of cell death. (167 aa)
	DAP	Uncharacterized protein. (83 aa)
	ENSCANP00000003670	Uncharacterized protein; Belongs to the GroES chaperonin family. (102 aa)
	BEX3	Brain expressed X-linked 3. (111 aa)
	ENSCANP00000003020	40S ribosomal protein S27. (84 aa)
	RPS27L	40S ribosomal protein S27. (97 aa)
	S100A9	Protein S100; Belongs to the S-100 family. (114 aa)
	ENSCANP00000001521	40S ribosomal protein S27. (84 aa)
	LOC105506133	Uncharacterized protein; Belongs to the GroES chaperonin family. (102 aa)
	F3	Coagulation factor III, tissue factor. (296 aa)
	SMAD3	Mothers against decapentaplegic homolog. (425 aa)

Your Current Organism:

Colobus angolensis

NCBI taxonomy Id: 336983
Other names: C. angolensis palliatus, Colobus angolensis palliatus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AIFM1	APAF1	ENSCANP00000035590	ENSCANP00000040110	Apoptosis inducing factor mitochondria associated 1.	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	0.527
AIFM1	BAK1	ENSCANP00000035590	ENSCANP00000021615	Apoptosis inducing factor mitochondria associated 1.	BCL2 antagonist/killer 1.	0.881
AIFM1	BAX	ENSCANP00000035590	ENSCANP00000028345	Apoptosis inducing factor mitochondria associated 1.	BCL2 associated X, apoptosis regulator.	0.853
AIFM1	BCL2L10	ENSCANP00000035590	ENSCANP00000035604	Apoptosis inducing factor mitochondria associated 1.	Uncharacterized protein.	0.524
AIFM1	BOK	ENSCANP00000035590	ENSCANP00000010162	Apoptosis inducing factor mitochondria associated 1.	BCL2 family apoptosis regulator BOK.	0.400
AIFM1	CASP9	ENSCANP00000035590	ENSCANP00000008717	Apoptosis inducing factor mitochondria associated 1.	Caspase 9; Belongs to the peptidase C14A family.	0.552
AIFM1	DIABLO	ENSCANP00000035590	ENSCANP00000031045	Apoptosis inducing factor mitochondria associated 1.	Uncharacterized protein.	0.552
APAF1	AIFM1	ENSCANP00000040110	ENSCANP00000035590	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	Apoptosis inducing factor mitochondria associated 1.	0.527
APAF1	BAK1	ENSCANP00000040110	ENSCANP00000021615	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	BCL2 antagonist/killer 1.	0.710
APAF1	BAX	ENSCANP00000040110	ENSCANP00000028345	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	BCL2 associated X, apoptosis regulator.	0.738
APAF1	BCL2L10	ENSCANP00000040110	ENSCANP00000035604	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	Uncharacterized protein.	0.687
APAF1	BCL2L11	ENSCANP00000040110	ENSCANP00000009631	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	Bcl-2-like protein 11; Induces apoptosis and anoikis. Belongs to the Bcl-2 family.	0.558
APAF1	BOK	ENSCANP00000040110	ENSCANP00000010162	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	BCL2 family apoptosis regulator BOK.	0.687
APAF1	CASP1	ENSCANP00000040110	ENSCANP00000024850	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	Caspase 1; Belongs to the peptidase C14A family.	0.874
APAF1	CASP10	ENSCANP00000040110	ENSCANP00000026452	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	Caspase 10; Belongs to the peptidase C14A family.	0.900
APAF1	CASP2	ENSCANP00000040110	ENSCANP00000035895	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	Caspase 2; Belongs to the peptidase C14A family.	0.909
APAF1	CASP8	ENSCANP00000040110	ENSCANP00000012395	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	Caspase 8; Belongs to the peptidase C14A family.	0.912
APAF1	CASP9	ENSCANP00000040110	ENSCANP00000008717	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	Caspase 9; Belongs to the peptidase C14A family.	0.997
APAF1	DIABLO	ENSCANP00000040110	ENSCANP00000031045	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	Uncharacterized protein.	0.886
APAF1	FASLG	ENSCANP00000040110	ENSCANP00000008105	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	Fas ligand; Belongs to the tumor necrosis factor family.	0.605