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| | BTBD11 | BTB domain containing 11. (1047 aa) |
| | ENSCANP00000036443 | TPR_REGION domain-containing protein. (356 aa) |
| | LTBP3 | Latent transforming growth factor beta binding protein 3. (1127 aa) |
| | SMAD2 | Mothers against decapentaplegic homolog. (467 aa) |
| | PTK2 | Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1096 aa) |
| | LPXN | Leupaxin; Transcriptional coactivator for androgen receptor (AR) and serum response factor (SRF). Contributes to the regulation of cell adhesion, spreading and cell migration and acts as a negative regulator in integrin-mediated cell adhesion events. Suppresses the integrin- induced tyrosine phosphorylation of paxillin (PXN). (386 aa) |
| | ID1 | Inhibitor of DNA binding 1, HLH protein. (154 aa) |
| | VIM | Vimentin; Belongs to the intermediate filament family. (468 aa) |
| | LNPEP | Leucyl and cystinyl aminopeptidase. (1025 aa) |
| | ITGA8 | Integrin subunit alpha 8; Belongs to the integrin alpha chain family. (1052 aa) |
| | SLC39A5 | Solute carrier family 39 member 5. (540 aa) |
| | CCDC142 | Coiled-coil domain containing 142. (750 aa) |
| | DLX3 | Distal-less homeobox 3. (287 aa) |
| | MAPK14 | Mitogen-activated protein kinase. (360 aa) |
| | TGFBRAP1 | Transforming growth factor beta receptor associated protein 1. (860 aa) |
| | INHBC | Inhibin subunit beta C. (352 aa) |
| | SRC | Tyrosine-protein kinase. (458 aa) |
| | RNF111 | Ring finger protein 111. (994 aa) |
| | MAGI2 | Membrane associated guanylate kinase, WW and PDZ domain containing 2. (1259 aa) |
| | TGFB3 | Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa) |
| | GDF3 | Growth differentiation factor 3. (364 aa) |
| | SKI | SKI proto-oncogene. (649 aa) |
| | HIVEP1 | Human immunodeficiency virus type I enhancer binding protein 1. (2719 aa) |
| | JUN | Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (246 aa) |
| | HEXA | Beta-hexosaminidase. (540 aa) |
| | BMP8B | TGF_BETA_2 domain-containing protein. (336 aa) |
| | ENSCANP00000030727 | Uncharacterized protein. (48 aa) |
| | INHA | Inhibin alpha chain; Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition; Belongs to the TGF-beta family. (366 aa) |
| | APPL1 | Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1. (658 aa) |
| | INHBE | Inhibin subunit beta E. (351 aa) |
| | CHST11 | Carbohydrate sulfotransferase. (352 aa) |
| | GCNT2 | Glucosaminyl (N-acetyl) transferase 2 (I blood group). (402 aa) |
| | TGFBR1 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (499 aa) |
| | DDX5 | DEAD-box helicase 5; Belongs to the DEAD box helicase family. (614 aa) |
| | SMAD4 | Mothers against decapentaplegic homolog. (552 aa) |
| | BMP10 | Bone morphogenetic protein 10. (424 aa) |
| | ENSCANP00000029034 | Uncharacterized protein. (145 aa) |
| | SMURF1 | E3 ubiquitin-protein ligase. (763 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (396 aa) |
| | ZCCHC12 | Zinc finger CCHC-type containing 12. (402 aa) |
| | LOC105516701 | TGF_BETA_2 domain-containing protein. (283 aa) |
| | AKAP3 | A-kinase anchoring protein 3. (876 aa) |
| | LRRC32 | Leucine rich repeat containing 32. (662 aa) |
| | ACVR2B | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (750 aa) |
| | SMURF2 | E3 ubiquitin-protein ligase. (734 aa) |
| | ZFYVE9 | Zinc finger FYVE domain-containing protein. (1409 aa) |
| | TGFB1I1 | Transforming growth factor beta-1-induced transcript 1 protein; Functions as a molecular adapter coordinating multiple protein-protein interactions at the focal adhesion complex and in the nucleus. Links various intracellular signaling modules to plasma membrane receptors and regulates the Wnt and TGFB signaling pathways. (461 aa) |
| | GDF5 | Growth differentiation factor 5. (499 aa) |
| | LTBP4 | Latent transforming growth factor beta binding protein 4. (1599 aa) |
| | FNTA | Farnesyltransferase, CAAX box, alpha. (321 aa) |
| | EXT1 | Exostosin glycosyltransferase 1; Belongs to the glycosyltransferase 47 family. (746 aa) |
| | NRROS | Negative regulator of reactive oxygen species. (692 aa) |
| | FAM83G | Family with sequence similarity 83 member G. (823 aa) |
| | BMP3 | Bone morphogenetic protein 3; Belongs to the TGF-beta family. (472 aa) |
| | HNF1A | HNF1 homeobox A. (662 aa) |
| | BMP7 | Bone morphogenetic protein 7. (431 aa) |
| | ACVR1B | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (506 aa) |
| | ZNF831 | Zinc finger protein 831. (1668 aa) |
| | STAT3 | Signal transducer and activator of transcription. (795 aa) |
| | ITGB5 | Integrin beta; Belongs to the integrin beta chain family. (792 aa) |
| | FKBP8 | Peptidylprolyl isomerase. (421 aa) |
| | NUP93 | Nuclear pore complex protein Nup93; Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance; Belongs to the nucleoporin interacting component (NIC) family. (880 aa) |
| | FERMT2 | Fermitin family member 2. (687 aa) |
| | CDH5 | Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins. (717 aa) |
| | RUNX2 | RUNX family transcription factor 2. (475 aa) |
| | ZMIZ1 | Zinc finger MIZ-type containing 1. (1067 aa) |
| | TGFB2 | Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa) |
| | COL3A1 | Collagen type III alpha 1 chain. (1466 aa) |
| | SLC33A1 | Solute carrier family 33 member 1. (550 aa) |
| | AMHR2 | Anti-Muellerian hormone type-2 receptor; On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for anti-Muellerian hormone. (573 aa) |
| | DLX5 | Distal-less homeobox 5. (289 aa) |
| | RGMB | Repulsive guidance molecule BMP co-receptor b. (401 aa) |
| | TWSG1 | Twisted gastrulation BMP signaling modulator 1. (223 aa) |
| | CITED2 | Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2. (278 aa) |
| | FOS | Fos proto-oncogene, AP-1 transcription factor subunit. (380 aa) |
| | FGF9 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa) |
| | ETV2 | ETS domain-containing protein. (155 aa) |
| | LOC105515879 | Uncharacterized protein. (397 aa) |
| | SMAD1 | Mothers against decapentaplegic homolog. (465 aa) |
| | PPM1L | Protein phosphatase, Mg2+/Mn2+ dependent 1L. (360 aa) |
| | SFRP2 | Secreted frizzled related protein 2. (295 aa) |
| | BMP15 | Bone morphogenetic protein 15. (393 aa) |
| | MSTN | Myostatin. (376 aa) |
| | NLK | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (527 aa) |
| | SMAD5 | Mothers against decapentaplegic homolog. (465 aa) |
| | ENSCANP00000016136 | Uncharacterized protein. (331 aa) |
| | GDF2 | Growth differentiation factor 2. (429 aa) |
| | MAPK3 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (380 aa) |
| | TGFBR3 | Transforming growth factor beta receptor 3. (860 aa) |
| | BMPER | BMP binding endothelial regulator. (685 aa) |
| | HFE | Homeostatic iron regulator; Belongs to the MHC class I family. (348 aa) |
| | WFIKKN2 | WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2. (576 aa) |
| | USP15 | Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (981 aa) |
| | GDF6 | Growth differentiation factor 6. (455 aa) |
| | BMP4 | Bone morphogenetic protein 4. (408 aa) |
| | GDF7 | Growth differentiation factor 7. (366 aa) |
| | TBXT | T-box transcription factor T. (435 aa) |
| | BMPR1A | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa) |
| | FUT8 | Alpha-(1,6)-fucosyltransferase; Catalyzes the addition of fucose in alpha 1-6 linkage to the first GlcNAc residue, next to the peptide chains in N-glycans. Belongs to the glycosyltransferase 23 family. (575 aa) |
| | BMP2 | Bone morphogenetic protein 2. (396 aa) |
| | ACVR1 | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (509 aa) |
| | ENSCANP00000012853 | C2 domain-containing protein. (51 aa) |
| | AFP | Alpha fetoprotein. (635 aa) |
| | FOXH1 | Forkhead box H1. (366 aa) |
| | FLCN | Folliculin. (579 aa) |
| | TMPRSS6 | Transmembrane serine protease 6; Belongs to the peptidase S1 family. (809 aa) |
| | RGMA | Repulsive guidance molecule BMP co-receptor a. (458 aa) |
| | USP9X | Ubiquitin specific peptidase 9 X-linked; Belongs to the peptidase C19 family. (2418 aa) |
| | HNF4A | Hepatocyte nuclear factor 4 alpha. (464 aa) |
| | COL1A2 | Collagen type I alpha 2 chain. (1366 aa) |
| | FMOD | Fibromodulin. (376 aa) |
| | RBM14 | RNA binding motif protein 14. (669 aa) |
| | LTBP2 | Latent transforming growth factor beta binding protein 2. (1821 aa) |
| | CHRD | Chordin. (871 aa) |
| | ACVRL1 | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (503 aa) |
| | CHRDL1 | Chordin like 1. (458 aa) |
| | HIPK2 | Homeodomain interacting protein kinase 2. (1197 aa) |
| | ITGB6 | Integrin beta; Belongs to the integrin beta chain family. (746 aa) |
| | PXN | Paxillin. (1076 aa) |
| | NOG | Noggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa) |
| | ZYX | Uncharacterized protein. (569 aa) |
| | TGFBR2 | TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa) |
| | ATF2 | Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa) |
| | LOC105521177 | TGF_BETA_2 domain-containing protein. (238 aa) |
| | COMP | Cartilage oligomeric matrix protein. (757 aa) |
| | TMEM100 | Transmembrane protein 100. (134 aa) |
| | INHBA | Inhibin subunit beta A. (426 aa) |
| | DSG4 | Desmoglein 4; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. (1052 aa) |
| | ACVR2A | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (515 aa) |
| | GDF10 | Bone morphogenetic protein 3; Belongs to the TGF-beta family. (474 aa) |
| | FURIN | Furin, paired basic amino acid cleaving enzyme; Belongs to the peptidase S8 family. (794 aa) |
| | SMAD7 | Mothers against decapentaplegic homolog. (431 aa) |
| | SOSTDC1 | Sclerostin domain containing 1. (230 aa) |
| | FST | Follistatin. (317 aa) |
| | SPART | Spartin. (666 aa) |
| | ENSCANP00000007072 | Uncharacterized protein. (436 aa) |
| | SOST | Sclerostin. (213 aa) |
| | GLG1 | Golgi glycoprotein 1. (1173 aa) |
| | PML | Promyelocytic leukemia. (882 aa) |
| | APPL2 | Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2. (670 aa) |
| | BMP5 | Bone morphogenetic protein 5. (454 aa) |
| | SIRT1 | Sirtuin 1. (600 aa) |
| | BMPR1B | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa) |
| | ACVR1C | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (489 aa) |
| | SMAD9 | Mothers against decapentaplegic homolog. (467 aa) |
| | DUSP22 | Dual specificity phosphatase 22; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (205 aa) |
| | NOTCH2 | Notch receptor 2. (2471 aa) |
| | TGFB1 | Transforming growth factor beta; Belongs to the TGF-beta family. (336 aa) |
| | BMP6 | Bone morphogenetic protein 6. (331 aa) |
| | PDCD4 | Programmed cell death 4. (470 aa) |
| | WNT1 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa) |
| | SKIL | SKI like proto-oncogene. (684 aa) |
| | ZNF8 | Zinc finger protein 8. (575 aa) |
| | TF | Transferrin; Belongs to the transferrin family. (698 aa) |
| | MTMR4 | Myotubularin related protein 4. (1195 aa) |
| | CITED1 | Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1. (219 aa) |
| | ITGB8 | Integrin beta; Belongs to the integrin beta chain family. (769 aa) |
| | SFRP1 | Secreted frizzled related protein 1. (314 aa) |
| | TGFBR3L | Transforming growth factor beta receptor 3 like. (253 aa) |
| | LEF1 | Lymphoid enhancer binding factor 1. (399 aa) |
| | SMAD3 | Mothers against decapentaplegic homolog. (425 aa) |
| | MEGF8 | Multiple EGF like domains 8. (2837 aa) |
| | BAMBI | BMP and activin membrane-bound inhibitor homolog; Negatively regulates TGF-beta signaling. Belongs to the BAMBI family. (260 aa) |
| | LOC105505188 | Uncharacterized protein. (569 aa) |
| | TGIF2 | TGFB induced factor homeobox 2. (237 aa) |
| | LOC105519161 | CFC domain-containing protein. (170 aa) |
| | ENG | Endoglin. (658 aa) |
| | HPGD | 15-hydroxyprostaglandin dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (266 aa) |
| | ADAM9 | ADAM metallopeptidase domain 9. (819 aa) |
| | JADE2 | Jade family PHD finger 2. (834 aa) |
| | GDF11 | Growth differentiation factor 11. (345 aa) |
| | STUB1 | STIP1 homology and U-box containing protein 1. (250 aa) |
| | BMPR2 | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1030 aa) |
| | HJV | Hemojuvelin BMP co-receptor. (425 aa) |
| | MSX1 | Msh homeobox 1. (199 aa) |
| | WNT5A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa) |
| | TDGF1 | Growth factor; Belongs to the EGF-CFC (Cripto-1/FRL1/Cryptic) family. (171 aa) |
| | ABL1 | Tyrosine-protein kinase. (1149 aa) |
| | LTBP1 | Latent transforming growth factor beta binding protein 1. (1510 aa) |
| | LOC105516700 | TGF_BETA_2 domain-containing protein. (311 aa) |
| | ENSCANP00000034037 | Uncharacterized protein. (118 aa) |
| | NODAL | Nodal growth differentiation factor. (347 aa) |
| | EGR1 | Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (527 aa) |
| | SPTBN1 | Spectrin beta chain; Belongs to the spectrin family. (2366 aa) |
| | PARP1 | Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1015 aa) |
| | SMPD3 | Sphingomyelin phosphodiesterase 3. (655 aa) |
| | NCEH1 | Neutral cholesterol ester hydrolase 1. (448 aa) |
| | ONECUT2 | One cut domain family member. (418 aa) |
| | PTPRK | Protein tyrosine phosphatase receptor type K. (1421 aa) |
