STRINGSTRING
DUSP2 DUSP2 SETD2 SETD2 GRB2 GRB2 EXT2 EXT2 COL6A1 COL6A1 FOXF1 FOXF1 ITGA8 ITGA8 FRS2 FRS2 ARMC5 ARMC5 LRP5 LRP5 ENSCANP00000038657 ENSCANP00000038657 CRB2 CRB2 MMP14 MMP14 ITGA2 ITGA2 AMOT AMOT CUL3 CUL3 SMAD2 SMAD2 ENSCANP00000036653 ENSCANP00000036653 TXNRD1 TXNRD1 SOX17 SOX17 SOX7 SOX7 NODAL NODAL TBX20 TBX20 ENSCANP00000034037 ENSCANP00000034037 EPHA2 EPHA2 ENSCANP00000033948 ENSCANP00000033948 COL11A1 COL11A1 TBX6 TBX6 MMP9 MMP9 LMBRD1 LMBRD1 EOMES EOMES WNT5A WNT5A RNF2 RNF2 BMPR2 BMPR2 COL12A1 COL12A1 GDF3 GDF3 EPB41L5 EPB41L5 DUSP1 DUSP1 CTR9 CTR9 ENSCANP00000030255 ENSCANP00000030255 LAMB1 LAMB1 LOC105515431 LOC105515431 ITGB4 ITGB4 LDB1 LDB1 SMAD4 SMAD4 TP53 TP53 DVL2 DVL2 WNT3A WNT3A NR4A3 NR4A3 SYF2 SYF2 ACVR2B ACVR2B RTF1 RTF1 SRF SRF HAND1 HAND1 CER1 CER1 SNAI1 SNAI1 MESP2 MESP2 PAF1 PAF1 NR0B1 NR0B1 ETS2 ETS2 ITGA3 ITGA3 TASOR TASOR EXT1 EXT1 ITGB3 ITGB3 HNF1A HNF1A GPC3 GPC3 BMP7 BMP7 MIXL1 MIXL1 AXIN1 AXIN1 EYA2 EYA2 ITGB5 ITGB5 APLN APLN TAF10 TAF10 LOC105512713 LOC105512713 TWSG1 TWSG1 FGFR2 FGFR2 SUPT20HL2 SUPT20HL2 WNT8B WNT8B ETV2 ETV2 KIF16B KIF16B SMAD1 SMAD1 SFRP2 SFRP2 LAMB3 LAMB3 EYA1 EYA1 DUSP4 DUSP4 PAX2 PAX2 RACK1 RACK1 ITGA5 ITGA5 HMGA2 HMGA2 ITGB2 ITGB2 MMP15 MMP15 BMP4 BMP4 SIX2 SIX2 HIRA HIRA UGDH UGDH TBXT TBXT LOC105505011 LOC105505011 BMPR1A BMPR1A ENSCANP00000013426 ENSCANP00000013426 COL4A2 COL4A2 ACVR1 ACVR1 LAMA3 LAMA3 WNT11 WNT11 CTNNB1 CTNNB1 TENM4 TENM4 ZBTB17 ZBTB17 WNT3 WNT3 LEO1 LEO1 FN1 FN1 FGF8 FGF8 OTX2 OTX2 DKK1 DKK1 LOC105511615 LOC105511615 MMP8 MMP8 KDM6B KDM6B KLF4 KLF4 HOXA11 HOXA11 ENSCANP00000006272 ENSCANP00000006272 TLX2 TLX2 ITGA7 ITGA7 ACVR2A ACVR2A FOXA2 FOXA2 GATA6 GATA6 ZIC3 ZIC3 INHBA INHBA LOC105503463 LOC105503463 NF2 NF2 SUPT20H SUPT20H TGFBR2 TGFBR2 COL8A1 COL8A1 DVL1 DVL1 NOG NOG TBX19 TBX19 MSGN1 MSGN1 COL7A1 COL7A1 ITGA4 ITGA4 ARFRP1 ARFRP1 POGLUT1 POGLUT1 PLPP3 PLPP3 CDC73 CDC73 DUSP5 DUSP5 APLNR APLNR SFRP1 SFRP1 LEF1 LEF1 ENSCANP00000000656 ENSCANP00000000656 SMAD3 SMAD3 MEGF8 MEGF8 APELA APELA EXOC4 EXOC4 LOC105506848 LOC105506848 ITGAV ITGAV
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
DUSP2Dual specificity phosphatase 2; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (262 aa)
SETD2SET domain containing 2, histone lysine methyltransferase. (2517 aa)
GRB2Uncharacterized protein. (156 aa)
EXT2Exostosin glycosyltransferase 2; Belongs to the glycosyltransferase 47 family. (751 aa)
COL6A1Collagen type VI alpha 1 chain. (935 aa)
FOXF1Forkhead box F1. (351 aa)
ITGA8Integrin subunit alpha 8; Belongs to the integrin alpha chain family. (1052 aa)
FRS2Fibroblast growth factor receptor substrate 2. (521 aa)
ARMC5Armadillo repeat containing 5. (1031 aa)
LRP5Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1611 aa)
ENSCANP00000038657Fork-head domain-containing protein. (200 aa)
CRB2Crumbs cell polarity complex component 2. (1287 aa)
MMP14Matrix metallopeptidase 14. (582 aa)
ITGA2Integrin subunit alpha 2; Belongs to the integrin alpha chain family. (1180 aa)
AMOTAngiomotin. (1084 aa)
CUL3Cullin 3; Belongs to the cullin family. (775 aa)
SMAD2Mothers against decapentaplegic homolog. (467 aa)
ENSCANP00000036653Uncharacterized protein. (158 aa)
TXNRD1Thioredoxin reductase 1. (611 aa)
SOX17SRY-box transcription factor 17. (412 aa)
SOX7SRY-box transcription factor 7. (386 aa)
NODALNodal growth differentiation factor. (347 aa)
TBX20T-box transcription factor 20. (447 aa)
ENSCANP00000034037Uncharacterized protein. (118 aa)
EPHA2EPH receptor A2. (976 aa)
ENSCANP00000033948Homeobox domain-containing protein. (141 aa)
COL11A1Collagen type XI alpha 1 chain. (1764 aa)
TBX6T-box transcription factor 6. (436 aa)
MMP9Matrix metallopeptidase 9. (707 aa)
LMBRD1LMBR1 domain containing 1. (540 aa)
EOMESEomesodermin. (705 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
RNF2Ring finger protein 2. (336 aa)
BMPR2Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1030 aa)
COL12A1Collagen type XII alpha 1 chain. (3063 aa)
GDF3Growth differentiation factor 3. (364 aa)
EPB41L5Erythrocyte membrane protein band 4.1 like 5. (671 aa)
DUSP1Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (367 aa)
CTR9CTR9 homolog, Paf1/RNA polymerase II complex component. (1173 aa)
ENSCANP00000030255Fork-head domain-containing protein. (189 aa)
LAMB1Laminin subunit beta 1. (1796 aa)
LOC10551543140S ribosomal protein S6; Belongs to the eukaryotic ribosomal protein eS6 family. (249 aa)
ITGB4Integrin beta. (1823 aa)
LDB1LIM domain binding 1. (411 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (396 aa)
DVL2Dishevelled segment polarity protein 2. (736 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
NR4A3Nuclear receptor subfamily 4 group A member 3. (549 aa)
SYF2SYF2 pre-mRNA splicing factor. (210 aa)
ACVR2BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (750 aa)
RTF1RTF1 homolog, Paf1/RNA polymerase II complex component. (644 aa)
SRFSerum response factor. (406 aa)
HAND1Heart and neural crest derivatives expressed 1. (215 aa)
CER1Cerberus 1, DAN family BMP antagonist. (267 aa)
SNAI1Snail family transcriptional repressor 1. (264 aa)
MESP2Mesoderm posterior bHLH transcription factor 2. (373 aa)
PAF1PAF1 homolog, Paf1/RNA polymerase II complex component. (531 aa)
NR0B1Nuclear receptor subfamily 0 group B member 1. (470 aa)
ETS2Protein C-ets-2; Transcription factor; Belongs to the ETS family. (469 aa)
ITGA3Integrin subunit alpha 3; Belongs to the integrin alpha chain family. (1064 aa)
TASORTranscription activation suppressor. (1507 aa)
EXT1Exostosin glycosyltransferase 1; Belongs to the glycosyltransferase 47 family. (746 aa)
ITGB3Integrin beta; Belongs to the integrin beta chain family. (784 aa)
HNF1AHNF1 homeobox A. (662 aa)
GPC3Glypican 3; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (603 aa)
BMP7Bone morphogenetic protein 7. (431 aa)
MIXL1Mix paired-like homeobox. (165 aa)
AXIN1Axin 1. (859 aa)
EYA2Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (538 aa)
ITGB5Integrin beta; Belongs to the integrin beta chain family. (792 aa)
APLNApelin. (77 aa)
TAF10Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family. (218 aa)
LOC105512713UDP-glucose 6-dehydrogenase; Involved in the biosynthesis of glycosaminoglycans; hyaluronan, chondroitin sulfate, and heparan sulfate. Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. (477 aa)
TWSG1Twisted gastrulation BMP signaling modulator 1. (223 aa)
FGFR2Fibroblast growth factor receptor. (838 aa)
SUPT20HL2Uncharacterized protein. (786 aa)
WNT8BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa)
ETV2ETS domain-containing protein. (155 aa)
KIF16BKinesin family member 16B; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1392 aa)
SMAD1Mothers against decapentaplegic homolog. (465 aa)
SFRP2Secreted frizzled related protein 2. (295 aa)
LAMB3Laminin subunit beta 3. (1172 aa)
EYA1Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (592 aa)
DUSP4Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (394 aa)
PAX2Paired box 2. (388 aa)
RACK1WD_REPEATS_REGION domain-containing protein. (241 aa)
ITGA5Integrin subunit alpha 5; Belongs to the integrin alpha chain family. (1049 aa)
HMGA2High mobility group AT-hook 2. (147 aa)
ITGB2Integrin beta. (769 aa)
MMP15Matrix metallopeptidase 15. (669 aa)
BMP4Bone morphogenetic protein 4. (408 aa)
SIX2SIX homeobox 2. (292 aa)
HIRAProtein HIRA; Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle; Belongs to the WD repeat HIR1 family. (1017 aa)
UGDHUDP-glucose 6-dehydrogenase; Involved in the biosynthesis of glycosaminoglycans; hyaluronan, chondroitin sulfate, and heparan sulfate. Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. (450 aa)
TBXTT-box transcription factor T. (435 aa)
LOC105505011WD_REPEATS_REGION domain-containing protein. (312 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
ENSCANP00000013426RING-type domain-containing protein. (324 aa)
COL4A2Collagen type IV alpha 2 chain. (1712 aa)
ACVR1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (509 aa)
LAMA3Laminin subunit alpha 3. (3235 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (330 aa)
CTNNB1Catenin beta 1. (781 aa)
TENM4Teneurin transmembrane protein 4. (2769 aa)
ZBTB17Zinc finger and BTB domain containing 17. (807 aa)
WNT3Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa)
LEO1LEO1 homolog, Paf1/RNA polymerase II complex component. (666 aa)
FN1Fibronectin 1. (2450 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (222 aa)
OTX2Orthodenticle homeobox 2. (297 aa)
DKK1Dickkopf WNT signaling pathway inhibitor 1. (266 aa)
LOC10551161540S ribosomal protein S6; Belongs to the eukaryotic ribosomal protein eS6 family. (216 aa)
MMP8Matrix metallopeptidase 8. (467 aa)
KDM6BLysine demethylase 6B. (1689 aa)
KLF4Kruppel like factor 4. (479 aa)
HOXA11Homeobox A11. (312 aa)
ENSCANP0000000627240S ribosomal protein S6; Belongs to the eukaryotic ribosomal protein eS6 family. (229 aa)
TLX2T cell leukemia homeobox 2. (284 aa)
ITGA7Integrin subunit alpha 7; Belongs to the integrin alpha chain family. (1181 aa)
ACVR2ASerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (515 aa)
FOXA2Forkhead box A2. (463 aa)
GATA6GATA binding protein 6. (462 aa)
ZIC3Zic family member 3. (466 aa)
INHBAInhibin subunit beta A. (426 aa)
LOC10550346340S ribosomal protein S6; Belongs to the eukaryotic ribosomal protein eS6 family. (249 aa)
NF2Neurofibromin 2. (561 aa)
SUPT20HSPT20 homolog, SAGA complex component. (810 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa)
COL8A1Collagen type VIII alpha 1 chain. (745 aa)
DVL1Dishevelled segment polarity protein 1. (694 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
TBX19T-box transcription factor 19. (448 aa)
MSGN1Mesogenin 1. (193 aa)
COL7A1Collagen type VII alpha 1 chain. (2729 aa)
ITGA4Integrin subunit alpha 4; Belongs to the integrin alpha chain family. (1032 aa)
ARFRP1ADP ribosylation factor related protein 1. (113 aa)
POGLUT1Protein O-glucosyltransferase 1. (392 aa)
PLPP3acidPPc domain-containing protein. (311 aa)
CDC73Cell division cycle 73. (531 aa)
DUSP5Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (318 aa)
APLNRApelin receptor; Belongs to the G-protein coupled receptor 1 family. (380 aa)
SFRP1Secreted frizzled related protein 1. (314 aa)
LEF1Lymphoid enhancer binding factor 1. (399 aa)
ENSCANP00000000656Uncharacterized protein. (178 aa)
SMAD3Mothers against decapentaplegic homolog. (425 aa)
MEGF8Multiple EGF like domains 8. (2837 aa)
APELAApelin receptor early endogenous ligand. (54 aa)
EXOC4Exocyst complex component 4. (974 aa)
LOC105506848Uncharacterized protein. (877 aa)
ITGAVIntegrin subunit alpha V; Belongs to the integrin alpha chain family. (1048 aa)
Your Current Organism:
Colobus angolensis
NCBI taxonomy Id: 336983
Other names: C. angolensis palliatus, Colobus angolensis palliatus
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