STRINGSTRING
NODAL NODAL RPL38 RPL38 TXNRD1 TXNRD1 ENSCANP00000036653 ENSCANP00000036653 ENSCANP00000036705 ENSCANP00000036705 SMAD2 SMAD2 POU4F1 POU4F1 TP63 TP63 LHX2 LHX2 SMAD4 SMAD4 BTK BTK MEST MEST WNT3A WNT3A ACVR2B ACVR2B SRF SRF HAND1 HAND1 SNAI1 SNAI1 MESP2 MESP2 IKZF3 IKZF3 ETS2 ETS2 ITGA3 ITGA3 EXT1 EXT1 ITGB3 ITGB3 HNF1A HNF1A BMP7 BMP7 ENSCANP00000022858 ENSCANP00000022858 AXIN1 AXIN1 EYA2 EYA2 TAF10 TAF10 TWSG1 TWSG1 CITED2 CITED2 NUP133 NUP133 ZFPM2 ZFPM2 FGFR2 FGFR2 ETV2 ETV2 IKZF1 IKZF1 SMAD1 SMAD1 SFRP2 SFRP2 SSBP3 SSBP3 EYA1 EYA1 PAX2 PAX2 LOC105524144 LOC105524144 ZFP36L1 ZFP36L1 HMGA2 HMGA2 YAP1 YAP1 TBX3 TBX3 LOC105505018 LOC105505018 BMP4 BMP4 SIX2 SIX2 TBXT TBXT BMPR1A BMPR1A ACVR1 ACVR1 TCF15 TCF15 FOXH1 FOXH1 WNT11 WNT11 ENSCANP00000010884 ENSCANP00000010884 WNT3 WNT3 LOC105510963 LOC105510963 FGF8 FGF8 DKK1 DKK1 IRX3 IRX3 ENSCANP00000007312 ENSCANP00000007312 KDM6B KDM6B DLL3 DLL3 KLF4 KLF4 HOXA11 HOXA11 SMO SMO TLX2 TLX2 ACVR2A ACVR2A DAND5 DAND5 ZIC3 ZIC3 INHBA INHBA NF2 NF2 PALB2 PALB2 ENSCANP00000003738 ENSCANP00000003738 TBX19 TBX19 MSGN1 MSGN1 GDF11 GDF11 EXOC4 EXOC4 APELA APELA SMAD3 SMAD3 CTDNEP1 CTDNEP1 ENSCANP00000000656 ENSCANP00000000656 LEF1 LEF1 POGLUT1 POGLUT1 NOG NOG ITGA2 ITGA2 CRB2 CRB2 ENSCANP00000038657 ENSCANP00000038657 OSR1 OSR1 SECTM1 SECTM1 ARMC5 ARMC5 ITGA8 ITGA8 FOXF1 FOXF1 TEAD2 TEAD2 EXT2 EXT2 SETD2 SETD2 ITGB4 ITGB4 PPP2CA PPP2CA ENSCANP00000030255 ENSCANP00000030255 SHH SHH EPB41L5 EPB41L5 GDF3 GDF3 BMX BMX BMPR2 BMPR2 OVOL1 OVOL1 WNT5A WNT5A EOMES EOMES LDB1 LDB1 TIE1 TIE1 TBX6 TBX6 ENSCANP00000033948 ENSCANP00000033948 EPHA2 EPHA2 TBX20 TBX20
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NODALNodal growth differentiation factor. (347 aa)
RPL38Uncharacterized protein; Belongs to the eukaryotic ribosomal protein eL38 family. (72 aa)
TXNRD1Thioredoxin reductase 1. (611 aa)
ENSCANP00000036653Uncharacterized protein. (158 aa)
ENSCANP00000036705Uncharacterized protein; Belongs to the eukaryotic ribosomal protein eL38 family. (61 aa)
SMAD2Mothers against decapentaplegic homolog. (467 aa)
POU4F1POU domain protein. (288 aa)
TP63Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (654 aa)
LHX2LIM homeobox 2. (406 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
BTKTyrosine-protein kinase. (692 aa)
MESTMesoderm specific transcript. (335 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
ACVR2BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (750 aa)
SRFSerum response factor. (406 aa)
HAND1Heart and neural crest derivatives expressed 1. (215 aa)
SNAI1Snail family transcriptional repressor 1. (264 aa)
MESP2Mesoderm posterior bHLH transcription factor 2. (373 aa)
IKZF3IKAROS family zinc finger 3. (509 aa)
ETS2Protein C-ets-2; Transcription factor; Belongs to the ETS family. (469 aa)
ITGA3Integrin subunit alpha 3; Belongs to the integrin alpha chain family. (1064 aa)
EXT1Exostosin glycosyltransferase 1; Belongs to the glycosyltransferase 47 family. (746 aa)
ITGB3Integrin beta; Belongs to the integrin beta chain family. (784 aa)
HNF1AHNF1 homeobox A. (662 aa)
BMP7Bone morphogenetic protein 7. (431 aa)
ENSCANP00000022858Uncharacterized protein; Belongs to the eukaryotic ribosomal protein eL38 family. (65 aa)
AXIN1Axin 1. (859 aa)
EYA2Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (538 aa)
TAF10Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family. (218 aa)
TWSG1Twisted gastrulation BMP signaling modulator 1. (223 aa)
CITED2Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2. (278 aa)
NUP133Nucleoporin 133. (1146 aa)
ZFPM2Zinc finger protein, FOG family member 2. (1137 aa)
FGFR2Fibroblast growth factor receptor. (838 aa)
ETV2ETS domain-containing protein. (155 aa)
IKZF1IKAROS family zinc finger 1. (519 aa)
SMAD1Mothers against decapentaplegic homolog. (465 aa)
SFRP2Secreted frizzled related protein 2. (295 aa)
SSBP3Single stranded DNA binding protein 3. (369 aa)
EYA1Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (592 aa)
PAX2Paired box 2. (388 aa)
LOC105524144FCP1 homology domain-containing protein. (198 aa)
ZFP36L1ZFP36 ring finger protein like 1. (338 aa)
HMGA2High mobility group AT-hook 2. (147 aa)
YAP1Yes associated protein 1. (479 aa)
TBX3T-box transcription factor 3. (743 aa)
LOC105505018Uncharacterized protein; Belongs to the eukaryotic ribosomal protein eL38 family. (64 aa)
BMP4Bone morphogenetic protein 4. (408 aa)
SIX2SIX homeobox 2. (292 aa)
TBXTT-box transcription factor T. (435 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
ACVR1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (509 aa)
TCF15Transcription factor 15. (164 aa)
FOXH1Forkhead box H1. (366 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (330 aa)
ENSCANP00000010884Uncharacterized protein. (338 aa)
WNT3Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa)
LOC105510963Serine/threonine-protein phosphatase. (291 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (222 aa)
DKK1Dickkopf WNT signaling pathway inhibitor 1. (266 aa)
IRX3Iroquois homeobox 3. (411 aa)
ENSCANP00000007312Uncharacterized protein. (298 aa)
KDM6BLysine demethylase 6B. (1689 aa)
DLL3Delta like canonical Notch ligand 3. (472 aa)
KLF4Kruppel like factor 4. (479 aa)
HOXA11Homeobox A11. (312 aa)
SMOSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (768 aa)
TLX2T cell leukemia homeobox 2. (284 aa)
ACVR2ASerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (515 aa)
DAND5DAN domain BMP antagonist family member 5. (189 aa)
ZIC3Zic family member 3. (466 aa)
INHBAInhibin subunit beta A. (426 aa)
NF2Neurofibromin 2. (561 aa)
PALB2Partner and localizer of BRCA2. (1161 aa)
ENSCANP00000003738Uncharacterized protein. (247 aa)
TBX19T-box transcription factor 19. (448 aa)
MSGN1Mesogenin 1. (193 aa)
GDF11Growth differentiation factor 11. (345 aa)
EXOC4Exocyst complex component 4. (974 aa)
APELAApelin receptor early endogenous ligand. (54 aa)
SMAD3Mothers against decapentaplegic homolog. (425 aa)
CTDNEP1CTD nuclear envelope phosphatase 1. (244 aa)
ENSCANP00000000656Uncharacterized protein. (178 aa)
LEF1Lymphoid enhancer binding factor 1. (399 aa)
POGLUT1Protein O-glucosyltransferase 1. (392 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
ITGA2Integrin subunit alpha 2; Belongs to the integrin alpha chain family. (1180 aa)
CRB2Crumbs cell polarity complex component 2. (1287 aa)
ENSCANP00000038657Fork-head domain-containing protein. (200 aa)
OSR1Odd-skipped related transcription factor 1. (266 aa)
SECTM1Secreted and transmembrane 1. (242 aa)
ARMC5Armadillo repeat containing 5. (1031 aa)
ITGA8Integrin subunit alpha 8; Belongs to the integrin alpha chain family. (1052 aa)
FOXF1Forkhead box F1. (351 aa)
TEAD2TEA domain transcription factor 2. (377 aa)
EXT2Exostosin glycosyltransferase 2; Belongs to the glycosyltransferase 47 family. (751 aa)
SETD2SET domain containing 2, histone lysine methyltransferase. (2517 aa)
ITGB4Integrin beta. (1823 aa)
PPP2CASerine/threonine-protein phosphatase. (275 aa)
ENSCANP00000030255Fork-head domain-containing protein. (189 aa)
SHHSonic hedgehog signaling molecule. (390 aa)
EPB41L5Erythrocyte membrane protein band 4.1 like 5. (671 aa)
GDF3Growth differentiation factor 3. (364 aa)
BMXTyrosine-protein kinase. (675 aa)
BMPR2Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1030 aa)
OVOL1Ovo like transcriptional repressor 1. (267 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
EOMESEomesodermin. (705 aa)
LDB1LIM domain binding 1. (411 aa)
TIE1Tyrosine kinase with immunoglobulin like and EGF like domains 1. (1138 aa)
TBX6T-box transcription factor 6. (436 aa)
ENSCANP00000033948Homeobox domain-containing protein. (141 aa)
EPHA2EPH receptor A2. (976 aa)
TBX20T-box transcription factor 20. (447 aa)
Your Current Organism:
Colobus angolensis
NCBI taxonomy Id: 336983
Other names: C. angolensis palliatus, Colobus angolensis palliatus
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