STRINGSTRING
CRHBP CRHBP LOC105516507 LOC105516507 MED1 MED1 JUNB JUNB DDR1 DDR1 LOC105526953 LOC105526953 TRO TRO ADCYAP1 ADCYAP1 DSG1 DSG1 MEN1 MEN1 ENSCANP00000001808 ENSCANP00000001808 PRLHR PRLHR ABCC8 ABCC8 IHH IHH LIF LIF HPGD HPGD CRH CRH VDR VDR FUT7 FUT7 TGFBR2 TGFBR2 CLDN4 CLDN4 PRDM1 PRDM1 BCL2 BCL2 TCF23 TCF23 LDOC1 LDOC1 HSD11B2 HSD11B2 ENSCANP00000005241 ENSCANP00000005241 ADRA2B ADRA2B SLC19A1 SLC19A1 RECK RECK ASH1L ASH1L IGFBP2 IGFBP2 TGFB1 TGFB1 EMP2 EMP2 PNOC PNOC NR2F2 NR2F2 TEAD4 TEAD4 GHRL GHRL ENDOU ENDOU AR AR PRL PRL STC1 STC1 STAT5B STAT5B CYP27B1 CYP27B1 LOC105525017 LOC105525017 SOD1 SOD1 AKT1 AKT1 CSMD2 CSMD2 PRDM14 PRDM14 SPP1 SPP1 ENSCANP00000015284 ENSCANP00000015284 LOC105522087 LOC105522087 AGRP AGRP ITGA5 ITGA5 KLF1 KLF1 STOX2 STOX2 RARA RARA ACOD1 ACOD1 OXTR OXTR FBLN1 FBLN1 SPHK2 SPHK2 EPYC EPYC PPARD PPARD PRLR PRLR FOS FOS PTGS2 PTGS2 TLE6 TLE6 CALCA CALCA CITED2 CITED2 LOC105507871 LOC105507871 TPPP3 TPPP3 GNAS GNAS GIP GIP HMX3 HMX3 SP3 SP3 ENSCANP00000023404 ENSCANP00000023404 LOC105521110 LOC105521110 BSG BSG TEAD3 TEAD3 ITGB3 ITGB3 ITGA3 ITGA3 ADM ADM PGF PGF RGS2 RGS2 FKBP4 FKBP4 ARG1 ARG1 COL16A1 COL16A1 WNT4 WNT4 NPPA NPPA IGFBP5 IGFBP5 ATP7A ATP7A A1CF A1CF ITGB4 ITGB4 TMED2 TMED2 GHSR GHSR CORIN CORIN PTN PTN PAPPA PAPPA LAMB1 LAMB1 CSMD1 CSMD1 ADCY7 ADCY7 CLIC5 CLIC5 MST1 MST1 STS STS VMP1 VMP1 EPO EPO TGFB3 TGFB3 BMPR2 BMPR2 PCSK5 PCSK5 ANGPT2 ANGPT2 MMP9 MMP9 DAZAP1 DAZAP1 FOSL1 FOSL1 NODAL NODAL PLA2G6 PLA2G6 PAM PAM FOSB FOSB ACSL4 ACSL4 IDO1 IDO1 ESR1 ESR1 EPN1 EPN1 AMBP AMBP SLC2A1 SLC2A1 LOC105525018 LOC105525018 ITGA2 ITGA2 TRIM28 TRIM28 LNPEP LNPEP EPOR EPOR TAC3 TAC3 SLC38A3 SLC38A3 HAVCR2 HAVCR2 MAGED2 MAGED2
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CRHBPCorticotropin-releasing factor-binding protein; Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy. Belongs to the CRF-binding protein family. (322 aa)
LOC105516507DUF4939 domain-containing protein. (113 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1576 aa)
JUNBJunB proto-oncogene, AP-1 transcription factor subunit. (347 aa)
DDR1Discoidin domain receptor tyrosine kinase 1. (894 aa)
LOC105526953Uncharacterized protein. (426 aa)
TROTrophinin. (1426 aa)
ADCYAP1Adenylate cyclase activating polypeptide 1. (176 aa)
DSG1Desmoglein 1; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. (1038 aa)
MEN1Menin 1. (610 aa)
ENSCANP00000001808Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family. (144 aa)
PRLHRProlactin releasing hormone receptor; Belongs to the G-protein coupled receptor 1 family. (370 aa)
ABCC8ATP binding cassette subfamily C member 8. (1577 aa)
IHHIndian hedgehog signaling molecule. (373 aa)
LIFLIF interleukin 6 family cytokine. (204 aa)
HPGD15-hydroxyprostaglandin dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (266 aa)
CRHCorticotropin releasing hormone. (200 aa)
VDRVitamin D receptor. (477 aa)
FUT7Fucosyltransferase 7. (342 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa)
CLDN4Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (209 aa)
PRDM1PR/SET domain 1. (825 aa)
BCL2BCL2 apoptosis regulator. (239 aa)
TCF23Transcription factor 23. (214 aa)
LDOC1LDOC1 regulator of NFKB signaling. (146 aa)
HSD11B2Hydroxysteroid 11-beta dehydrogenase 2. (331 aa)
ENSCANP00000005241Uncharacterized protein. (80 aa)
ADRA2BAdrenoceptor alpha 2B. (452 aa)
SLC19A1Solute carrier family 19 member 1. (586 aa)
RECKReversion inducing cysteine rich protein with kazal motifs. (971 aa)
ASH1LASH1 like histone lysine methyltransferase. (2969 aa)
IGFBP2Insulin like growth factor binding protein 2. (181 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (336 aa)
EMP2Epithelial membrane protein 2; Functions as a key regulator of cell membrane composition by regulating proteins surface expression. Also, plays a role in regulation of processes including cell migration, cell proliferation, cell contraction and cell adhesion; Belongs to the PMP-22/EMP/MP20 family. (200 aa)
PNOCPrepronociceptin. (176 aa)
NR2F2Nuclear receptor subfamily 2 group F member 2. (366 aa)
TEAD4Transcriptional enhancer factor TEF-3; Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. (434 aa)
GHRLGhrelin and obestatin prepropeptide. (117 aa)
ENDOUEndonuclease, poly(U) specific. (411 aa)
ARAndrogen receptor. (897 aa)
PRLProlactin. (227 aa)
STC1Stanniocalcin 1. (247 aa)
STAT5BSignal transducer and activator of transcription. (756 aa)
CYP27B1Cytochrome P450 family 27 subfamily B member 1; Belongs to the cytochrome P450 family. (509 aa)
LOC105525017Uncharacterized protein. (424 aa)
SOD1Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family. (154 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (488 aa)
CSMD2CUB and Sushi multiple domains 2. (3537 aa)
PRDM14PR/SET domain 14. (580 aa)
SPP1Secreted phosphoprotein 1. (314 aa)
ENSCANP00000015284GOLD domain-containing protein. (93 aa)
LOC105522087Uncharacterized protein. (379 aa)
AGRPAgouti related neuropeptide. (132 aa)
ITGA5Integrin subunit alpha 5; Belongs to the integrin alpha chain family. (1049 aa)
KLF1Kruppel like factor 1. (362 aa)
STOX2Storkhead box 2. (926 aa)
RARARetinoic acid receptor alpha. (478 aa)
ACOD1Aconitate decarboxylase 1. (481 aa)
OXTROxytocin receptor; Receptor for oxytocin. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (389 aa)
FBLN1Fibulin-1; Incorporated into fibronectin-containing matrix fibers. May play a role in cell adhesion and migration along protein fibers within the extracellular matrix (ECM). Could be important for certain developmental processes and contribute to the supramolecular organization of ECM architecture, in particular to those of basement membranes. (710 aa)
SPHK2Sphingosine kinase 2. (658 aa)
EPYCEpiphycan. (322 aa)
PPARDPeroxisome proliferator activated receptor delta. (441 aa)
PRLRProlactin receptor; This is a receptor for the anterior pituitary hormone prolactin. (619 aa)
FOSFos proto-oncogene, AP-1 transcription factor subunit. (380 aa)
PTGS2Prostaglandin-endoperoxide synthase 2. (604 aa)
TLE6WD_REPEATS_REGION domain-containing protein. (299 aa)
CALCACalcitonin related polypeptide alpha. (142 aa)
CITED2Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2. (278 aa)
LOC105507871Uncharacterized protein. (429 aa)
TPPP3Tubulin polymerization promoting protein family member 3. (176 aa)
GNASGNAS complex locus. (913 aa)
GIPGLUCAGON domain-containing protein. (79 aa)
HMX3H6 family homeobox 3. (327 aa)
SP3Sp3 transcription factor. (714 aa)
ENSCANP00000023404Uncharacterized protein. (400 aa)
LOC105521110Uncharacterized protein. (202 aa)
BSGBasigin (Ok blood group). (373 aa)
TEAD3Transcriptional enhancer factor TEF-5; Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. (435 aa)
ITGB3Integrin beta; Belongs to the integrin beta chain family. (784 aa)
ITGA3Integrin subunit alpha 3; Belongs to the integrin alpha chain family. (1064 aa)
ADMAdrenomedullin. (185 aa)
PGFPlacental growth factor; Belongs to the PDGF/VEGF growth factor family. (200 aa)
RGS2Regulator of G protein signaling 2. (211 aa)
FKBP4Peptidylprolyl isomerase. (424 aa)
ARG1Arginase. (322 aa)
COL16A1Collagen type XVI alpha 1 chain. (1604 aa)
WNT4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (345 aa)
NPPANatriuretic peptide A. (153 aa)
IGFBP5Insulin like growth factor binding protein 5. (272 aa)
ATP7AATPase copper transporting alpha. (1500 aa)
A1CFAPOBEC1 complementation factor. (607 aa)
ITGB4Integrin beta. (1823 aa)
TMED2Transmembrane p24 trafficking protein 2. (116 aa)
GHSRGrowth hormone secretagogue receptor; Belongs to the G-protein coupled receptor 1 family. (366 aa)
CORINCorin, serine peptidase. (1042 aa)
PTNPleiotrophin. (172 aa)
PAPPAPappalysin 1. (1552 aa)
LAMB1Laminin subunit beta 1. (1796 aa)
CSMD1CUB and Sushi multiple domains 1. (3565 aa)
ADCY7Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1083 aa)
CLIC5Chloride intracellular channel protein; Belongs to the chloride channel CLIC family. (251 aa)
MST1Macrophage stimulating 1; Belongs to the peptidase S1 family. Plasminogen subfamily. (725 aa)
STSSteroid sulfatase. (583 aa)
VMP1Vacuole membrane protein 1. (398 aa)
EPOErythropoietin; Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. Belongs to the EPO/TPO family. (192 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
BMPR2Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1030 aa)
PCSK5Proprotein convertase subtilisin/kexin type 5; Belongs to the peptidase S8 family. (1758 aa)
ANGPT2Angiopoietin 2. (496 aa)
MMP9Matrix metallopeptidase 9. (707 aa)
DAZAP1DAZ associated protein 1. (408 aa)
FOSL1FOS like 1, AP-1 transcription factor subunit. (271 aa)
NODALNodal growth differentiation factor. (347 aa)
PLA2G6Phospholipase A2 group VI. (806 aa)
PAMPeptidylglycine alpha-amidating monooxygenase. (905 aa)
FOSBFosB proto-oncogene, AP-1 transcription factor subunit. (338 aa)
ACSL4Acyl-CoA synthetase long chain family member 4. (711 aa)
IDO1Indoleamine 2,3-dioxygenase 1. (403 aa)
ESR1Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (595 aa)
EPN1Epsin 1. (662 aa)
AMBPAlpha-1-microglobulin/bikunin precursor. (352 aa)
SLC2A1Solute carrier family 2 member 1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (486 aa)
LOC105525018Uncharacterized protein. (426 aa)
ITGA2Integrin subunit alpha 2; Belongs to the integrin alpha chain family. (1180 aa)
TRIM28Tripartite motif containing 28. (823 aa)
LNPEPLeucyl and cystinyl aminopeptidase. (1025 aa)
EPORErythropoietin receptor; Receptor for erythropoietin. (508 aa)
TAC3Tachykinin 3. (121 aa)
SLC38A3Solute carrier family 38 member 3. (504 aa)
HAVCR2Hepatitis A virus cellular receptor 2. (293 aa)
MAGED2MAGE family member D2. (604 aa)
Your Current Organism:
Colobus angolensis
NCBI taxonomy Id: 336983
Other names: C. angolensis palliatus, Colobus angolensis palliatus
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