STRINGSTRING
ACVR2A ACVR2A RFX3 RFX3 DNAAF1 DNAAF1 NEK8 NEK8 SMAD3 SMAD3 MEGF8 MEGF8 DNAAF2 DNAAF2 ALDH1A2 ALDH1A2 PKD2 PKD2 LOC105519161 LOC105519161 ENG ENG FOLR1 FOLR1 IHH IHH DYNC2LI1 DYNC2LI1 DAAM2 DAAM2 ENSCANP00000003738 ENSCANP00000003738 C2CD3 C2CD3 NDRG4 NDRG4 TGFBR2 TGFBR2 DYNC2H1 DYNC2H1 TBX2 TBX2 TMEM107 TMEM107 TTC25 TTC25 ZIC3 ZIC3 DAND5 DAND5 BBS7 BBS7 ZFR ZFR CFAP53 CFAP53 SMO SMO GALNT11 GALNT11 MEF2C MEF2C DRC1 DRC1 DPCD DPCD CFAP45 CFAP45 DNAH11 DNAH11 NKX2-5 NKX2-5 FOXN4 FOXN4 FGF10 FGF10 NOTCH2 NOTCH2 ANKS6 ANKS6 OFD1 OFD1 FGF8 FGF8 MICALCL MICALCL ENSCANP00000011729 ENSCANP00000011729 FOXH1 FOXH1 C15orf65 C15orf65 MICAL2 MICAL2 ACVR1 ACVR1 FOXJ1 FOXJ1 NOTO NOTO DNAI1 DNAI1 PCSK6 PCSK6 DNAAF4 DNAAF4 TBXT TBXT BMP4 BMP4 GAS8 GAS8 RPGRIP1L RPGRIP1L TBX3 TBX3 SUFU SUFU ENSCANP00000015284 ENSCANP00000015284 PITX2 PITX2 LBX1 LBX1 PSKH1 PSKH1 LMLN2 LMLN2 CFAP52 CFAP52 KIF3B KIF3B MMP21 MMP21 WNT8B WNT8B NPHP3 NPHP3 CC2D2A CC2D2A OVOL2 OVOL2 CITED2 CITED2 STIL STIL SETDB2 SETDB2 ENKUR ENKUR MKS1 MKS1 ARL13B ARL13B ENSCANP00000022667 ENSCANP00000022667 NBL1 NBL1 ALG5 ALG5 RIPPLY2 RIPPLY2 IFT74 IFT74 PSEN1 PSEN1 CER1 CER1 ASB2 ASB2 HAND1 HAND1 SRF SRF DLL1 DLL1 C9orf116 C9orf116 HAND2 HAND2 DISP1 DISP1 LRRC6 LRRC6 ACVR2B ACVR2B NOTCH1 NOTCH1 IFT140 IFT140 WNT3A WNT3A ENSCANP00000028625 ENSCANP00000028625 HIF1A HIF1A CLUAP1 CLUAP1 BICC1 BICC1 ENSCANP00000029034 ENSCANP00000029034 DAW1 DAW1 TMED2 TMED2 IFT57 IFT57 MIB1 MIB1 SHH SHH ZFR2 ZFR2 BBS4 BBS4 CCDC151 CCDC151 DNAAF3 DNAAF3 DNAH5 DNAH5 AP1B1 AP1B1 NKX3-2 NKX3-2 TBC1D32 TBC1D32 WNT5A WNT5A TDGF1 TDGF1 IFT52 IFT52 TBX6 TBX6 ENSCANP00000034037 ENSCANP00000034037 TBX20 TBX20 NODAL NODAL VANGL2 VANGL2 PKD1L1 PKD1L1 CCDC103 CCDC103 SOX17 SOX17 CCDC39 CCDC39 ARMC4 ARMC4 GATA4 GATA4 AHI1 AHI1 RTTN RTTN FOXF1 FOXF1 DNAI2 DNAI2 CCDC40 CCDC40
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ACVR2ASerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (515 aa)
RFX3Regulatory factor X3. (777 aa)
DNAAF1Dynein assembly factor 1, axonemal. (692 aa)
NEK8NIMA related kinase 8. (692 aa)
SMAD3Mothers against decapentaplegic homolog. (425 aa)
MEGF8Multiple EGF like domains 8. (2837 aa)
DNAAF2Protein kintoun; Required for cytoplasmic pre-assembly of axonemal dyneins, thereby playing a central role in motility in cilia and flagella. Involved in pre-assembly of dynein arm complexes in the cytoplasm before intraflagellar transport loads them for the ciliary compartment. (832 aa)
ALDH1A2Aldehyde dehydrogenase 1 family member A2; Belongs to the aldehyde dehydrogenase family. (524 aa)
PKD2Polycystin 2, transient receptor potential cation channel. (780 aa)
LOC105519161CFC domain-containing protein. (170 aa)
ENGEndoglin. (658 aa)
FOLR1Folate receptor alpha. (257 aa)
IHHIndian hedgehog signaling molecule. (373 aa)
DYNC2LI1Dynein cytoplasmic 2 light intermediate chain 1. (351 aa)
DAAM2Dishevelled associated activator of morphogenesis 2. (1077 aa)
ENSCANP00000003738Uncharacterized protein. (247 aa)
C2CD3C2 domain containing 3 centriole elongation regulator. (2353 aa)
NDRG4NDRG family member 4. (378 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa)
DYNC2H1Dynein cytoplasmic 2 heavy chain 1. (4248 aa)
TBX2T-box transcription factor 2. (590 aa)
TMEM107Transmembrane protein 107. (146 aa)
TTC25Tetratricopeptide repeat domain 25. (672 aa)
ZIC3Zic family member 3. (466 aa)
DAND5DAN domain BMP antagonist family member 5. (189 aa)
BBS7Bardet-Biedl syndrome 7 protein homolog; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. (715 aa)
ZFRZinc finger RNA binding protein. (1074 aa)
CFAP53Cilia and flagella associated protein 53. (514 aa)
SMOSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (768 aa)
GALNT11Polypeptide N-acetylgalactosaminyltransferase. (608 aa)
MEF2CMyocyte enhancer factor 2C. (483 aa)
DRC1Dynein regulatory complex subunit 1. (740 aa)
DPCDDeleted in primary ciliary dyskinesia homolog (mouse). (189 aa)
CFAP45Cilia and flagella associated protein 45. (551 aa)
DNAH11Dynein axonemal heavy chain 11. (4505 aa)
NKX2-5NK2 homeobox 5. (324 aa)
FOXN4Forkhead box N4. (517 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
NOTCH2Notch receptor 2. (2471 aa)
ANKS6Ankyrin repeat and sterile alpha motif domain containing 6. (778 aa)
OFD1OFD1 centriole and centriolar satellite protein. (1013 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (222 aa)
MICALCLBMERB domain-containing protein. (695 aa)
ENSCANP00000011729DZF domain-containing protein. (114 aa)
FOXH1Forkhead box H1. (366 aa)
C15orf65Chromosome 15 open reading frame 65. (121 aa)
MICAL2Microtubule associated monooxygenase, calponin and LIM domain containing 2. (1124 aa)
ACVR1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (509 aa)
FOXJ1Forkhead box J1. (389 aa)
NOTONotochord homeobox. (138 aa)
DNAI1Dynein axonemal intermediate chain 1. (704 aa)
PCSK6Proprotein convertase subtilisin/kexin type 6; Belongs to the peptidase S8 family. (928 aa)
DNAAF4Dynein axonemal assembly factor 4. (361 aa)
TBXTT-box transcription factor T. (435 aa)
BMP4Bone morphogenetic protein 4. (408 aa)
GAS8Growth arrest specific 8. (457 aa)
RPGRIP1LRPGRIP1 like. (1313 aa)
TBX3T-box transcription factor 3. (743 aa)
SUFUSuppressor of fused homolog; Negative regulator in the hedgehog signaling pathway. Down- regulates GLI1-mediated transactivation of target genes. Part of a corepressor complex that acts on DNA-bound GLI1. May also act by linking GLI1 to BTRC and thereby targeting GLI1 to degradation by the proteasome. Sequesters GLI1, GLI2 and GLI3 in the cytoplasm, this effect is overcome by binding of STK36 to both SUFU and a GLI protein. Negative regulator of beta-catenin signaling. Regulates the formation of either the repressor form (GLI3R) or the activator form (GLI3A) of the full-length form of [...] (519 aa)
ENSCANP00000015284GOLD domain-containing protein. (93 aa)
PITX2Homeobox protein. (325 aa)
LBX1Ladybird homeobox 1. (281 aa)
PSKH1Protein serine kinase H1; Belongs to the protein kinase superfamily. (424 aa)
LMLN2Leishmanolysin-like peptidase. (771 aa)
CFAP52Cilia and flagella associated protein 52. (569 aa)
KIF3BKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (747 aa)
MMP21Matrix metallopeptidase 21. (486 aa)
WNT8BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa)
NPHP3TPR_REGION domain-containing protein. (1330 aa)
CC2D2ACoiled-coil and C2 domain containing 2A. (1620 aa)
OVOL2Ovo like zinc finger 2. (252 aa)
CITED2Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2. (278 aa)
STILSTIL centriolar assembly protein. (1242 aa)
SETDB2SET domain bifurcated histone lysine methyltransferase 2. (699 aa)
ENKUREnkurin, TRPC channel interacting protein. (256 aa)
MKS1MKS transition zone complex subunit 1. (559 aa)
ARL13BADP ribosylation factor like GTPase 13B. (428 aa)
ENSCANP00000022667LisH domain-containing protein. (144 aa)
NBL1NBL1, DAN family BMP antagonist. (215 aa)
ALG5ALG5 dolichyl-phosphate beta-glucosyltransferase. (324 aa)
RIPPLY2Ripply transcriptional repressor 2. (128 aa)
IFT74Intraflagellar transport 74. (599 aa)
PSEN1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (463 aa)
CER1Cerberus 1, DAN family BMP antagonist. (267 aa)
ASB2Ankyrin repeat and SOCS box containing 2. (635 aa)
HAND1Heart and neural crest derivatives expressed 1. (215 aa)
SRFSerum response factor. (406 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (723 aa)
C9orf116Chromosome 9 open reading frame 116. (136 aa)
HAND2Uncharacterized protein. (66 aa)
DISP1Dispatched RND transporter family member 1. (1524 aa)
LRRC6Leucine rich repeat containing 6. (536 aa)
ACVR2BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (750 aa)
NOTCH1Notch receptor 1. (2559 aa)
IFT140Intraflagellar transport 140. (1470 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
ENSCANP00000028625Uncharacterized protein. (291 aa)
HIF1AHypoxia inducible factor 1 subunit alpha. (827 aa)
CLUAP1Clusterin associated protein 1. (433 aa)
BICC1BicC family RNA binding protein 1. (935 aa)
ENSCANP00000029034Uncharacterized protein. (145 aa)
DAW1Dynein assembly factor with WD repeats 1. (400 aa)
TMED2Transmembrane p24 trafficking protein 2. (116 aa)
IFT57Intraflagellar transport 57. (428 aa)
MIB1Mindbomb E3 ubiquitin protein ligase 1. (1006 aa)
SHHSonic hedgehog signaling molecule. (390 aa)
ZFR2Zinc finger RNA binding protein 2. (904 aa)
BBS4Bardet-Biedl syndrome 4. (519 aa)
CCDC151Coiled-coil domain containing 151. (595 aa)
DNAAF3Uncharacterized protein. (470 aa)
DNAH5Dynein axonemal heavy chain 5. (4624 aa)
AP1B1Adaptor related protein complex 1 subunit beta 1. (942 aa)
NKX3-2NK3 homeobox 2. (284 aa)
TBC1D32TBC1 domain family member 32. (1261 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
TDGF1Growth factor; Belongs to the EGF-CFC (Cripto-1/FRL1/Cryptic) family. (171 aa)
IFT52Intraflagellar transport 52. (420 aa)
TBX6T-box transcription factor 6. (436 aa)
ENSCANP00000034037Uncharacterized protein. (118 aa)
TBX20T-box transcription factor 20. (447 aa)
NODALNodal growth differentiation factor. (347 aa)
VANGL2Vang-like protein. (547 aa)
PKD1L1Polycystin 1 like 1, transient receptor potential channel interacting. (2837 aa)
CCDC103Coiled-coil domain containing 103. (242 aa)
SOX17SRY-box transcription factor 17. (412 aa)
CCDC39Coiled-coil domain containing 39. (942 aa)
ARMC4Armadillo repeat containing 4. (1044 aa)
GATA4GATA binding protein 4. (236 aa)
AHI1Abelson helper integration site 1. (1196 aa)
RTTNRotatin. (2157 aa)
FOXF1Forkhead box F1. (351 aa)
DNAI2Dynein axonemal intermediate chain 2. (605 aa)
CCDC40Coiled-coil domain containing 40. (1135 aa)
Your Current Organism:
Colobus angolensis
NCBI taxonomy Id: 336983
Other names: C. angolensis palliatus, Colobus angolensis palliatus
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