STRINGSTRING
BMPR1A BMPR1A PRRX1 PRRX1 ZEB1 ZEB1 WNT11 WNT11 CTNNB1 CTNNB1 CHRD CHRD SMO SMO FGFR2 FGFR2 TGFBR2 TGFBR2 FOXF1 FOXF1 LRP5 LRP5 SOX9 SOX9 KDR KDR NFIB NFIB WNT5A WNT5A SHOX2 SHOX2 PHF14 PHF14 SHH SHH CTNNBIP1 CTNNBIP1 STAT1 STAT1 LMNA LMNA ENSCANP00000003738 ENSCANP00000003738 IHH IHH FGF9 FGF9 WNT2 WNT2 BMP4 BMP4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
PRRX1Paired related homeobox 1. (245 aa)
ZEB1Zinc finger E-box binding homeobox 1. (1124 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (330 aa)
CTNNB1Catenin beta 1. (781 aa)
CHRDChordin. (871 aa)
SMOSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (768 aa)
FGFR2Fibroblast growth factor receptor. (838 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa)
FOXF1Forkhead box F1. (351 aa)
LRP5Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1611 aa)
SOX9SRY-box transcription factor 9. (509 aa)
KDRKinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1356 aa)
NFIBNuclear factor 1; Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. (570 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
SHOX2Short stature homeobox 2. (221 aa)
PHF14PHD finger protein 14. (948 aa)
SHHSonic hedgehog signaling molecule. (390 aa)
CTNNBIP1Catenin beta interacting protein 1. (81 aa)
STAT1Signal transducer and activator of transcription. (765 aa)
LMNALamin A/C; Belongs to the intermediate filament family. (706 aa)
ENSCANP00000003738Uncharacterized protein. (247 aa)
IHHIndian hedgehog signaling molecule. (373 aa)
FGF9Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
WNT2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (360 aa)
BMP4Bone morphogenetic protein 4. (408 aa)
Your Current Organism:
Colobus angolensis
NCBI taxonomy Id: 336983
Other names: C. angolensis palliatus, Colobus angolensis palliatus
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