STRINGSTRING
CSF2 CSF2 MAPK9 MAPK9 MSR1 MSR1 APOB APOB ALOX15B ALOX15B CD36 CD36 AGTR1 AGTR1 PF4 PF4 LPL LPL AGT AGT CSF1 CSF1 NFKB1 NFKB1 PLA2G5 PLA2G5 PLA2G3 PLA2G3 IL18 IL18 PLA2G2A PLA2G2A
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CSF2Colony stimulating factor 2. (144 aa)
MAPK9Mitogen-activated protein kinase. (399 aa)
MSR1Macrophage scavenger receptor 1. (451 aa)
APOBApolipoprotein B. (4555 aa)
ALOX15BArachidonate 15-lipoxygenase type B. (676 aa)
CD36CD36 molecule; Belongs to the CD36 family. (472 aa)
AGTR1Angiotensin II receptor type 1; Belongs to the G-protein coupled receptor 1 family. (394 aa)
PF4C-X-C motif chemokine. (101 aa)
LPLLipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans. (475 aa)
AGTAngiotensinogen; Belongs to the serpin family. (485 aa)
CSF1Macrophage colony-stimulating factor 1; Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female [...] (551 aa)
NFKB1Nuclear factor kappa B subunit 1. (970 aa)
PLA2G5Phospholipase A(2). (138 aa)
PLA2G3Phospholipase A2 group III. (509 aa)
IL18Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family. (193 aa)
PLA2G2APhospholipase A(2). (144 aa)
Your Current Organism:
Colobus angolensis
NCBI taxonomy Id: 336983
Other names: C. angolensis palliatus, Colobus angolensis palliatus
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