STRINGSTRING
ACVRL1 ACVRL1 ACVR1 ACVR1 BMP2 BMP2 DAB2 DAB2 BMPR1A BMPR1A GDF7 GDF7 BMP4 BMP4 GDF6 GDF6 HFE HFE GDF2 GDF2 BMP15 BMP15 TWSG1 TWSG1 TGFB2 TGFB2 RBPMS RBPMS BMP7 BMP7 BMP3 BMP3 GDF5 GDF5 LOC105516701 LOC105516701 BMP10 BMP10 SMAD4 SMAD4 GDF11 GDF11 TGFBR1 TGFBR1 INHBE INHBE INHA INHA BMP8B BMP8B ENG ENG SDCBP SDCBP GDF3 GDF3 TGFB3 TGFB3 BMPR2 BMPR2 LOC105516700 LOC105516700 NODAL NODAL INHBC INHBC ENSCANP00000004166 ENSCANP00000004166 TGFBR2 TGFBR2 LOC105521177 LOC105521177 INHBA INHBA ACVR2A ACVR2A ENSCANP00000006850 ENSCANP00000006850 GDF10 GDF10 BMP5 BMP5 TGFB1 TGFB1 BMP6 BMP6
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ACVRL1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (503 aa)
ACVR1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (509 aa)
BMP2Bone morphogenetic protein 2. (396 aa)
DAB2DAB adaptor protein 2. (770 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
GDF7Growth differentiation factor 7. (366 aa)
BMP4Bone morphogenetic protein 4. (408 aa)
GDF6Growth differentiation factor 6. (455 aa)
HFEHomeostatic iron regulator; Belongs to the MHC class I family. (348 aa)
GDF2Growth differentiation factor 2. (429 aa)
BMP15Bone morphogenetic protein 15. (393 aa)
TWSG1Twisted gastrulation BMP signaling modulator 1. (223 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
RBPMSRNA binding protein, mRNA processing factor. (202 aa)
BMP7Bone morphogenetic protein 7. (431 aa)
BMP3Bone morphogenetic protein 3; Belongs to the TGF-beta family. (472 aa)
GDF5Growth differentiation factor 5. (499 aa)
LOC105516701TGF_BETA_2 domain-containing protein. (283 aa)
BMP10Bone morphogenetic protein 10. (424 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
GDF11Growth differentiation factor 11. (345 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (499 aa)
INHBEInhibin subunit beta E. (351 aa)
INHAInhibin alpha chain; Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition; Belongs to the TGF-beta family. (366 aa)
BMP8BTGF_BETA_2 domain-containing protein. (336 aa)
ENGEndoglin. (658 aa)
SDCBPSyndecan binding protein. (318 aa)
GDF3Growth differentiation factor 3. (364 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
BMPR2Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1030 aa)
LOC105516700TGF_BETA_2 domain-containing protein. (311 aa)
NODALNodal growth differentiation factor. (347 aa)
INHBCInhibin subunit beta C. (352 aa)
ENSCANP00000004166PDZ domain-containing protein. (294 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa)
LOC105521177TGF_BETA_2 domain-containing protein. (238 aa)
INHBAInhibin subunit beta A. (426 aa)
ACVR2ASerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (515 aa)
ENSCANP00000006850PDZ domain-containing protein. (282 aa)
GDF10Bone morphogenetic protein 3; Belongs to the TGF-beta family. (474 aa)
BMP5Bone morphogenetic protein 5. (454 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (336 aa)
BMP6Bone morphogenetic protein 6. (331 aa)
Your Current Organism:
Colobus angolensis
NCBI taxonomy Id: 336983
Other names: C. angolensis palliatus, Colobus angolensis palliatus
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